Physician Awareness of Immune Responses to Polyethylene Glycol-Drug Conjugates

Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k

(2017) Valerie Plant et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population

(2016) Qi Yang et al.   ANALYTICAL CHEMISTRY

Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer

(2016) Thomas J. Povsic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer

(2016) Nancy J. Ganson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

New low-volume resuscitation solutions containing PEG-20k

(2015) Dan Parrish et al.   Journal of Trauma and Acute Care Surgery

Anti-PEG immunity: emergence, characteristics, and unaddressed questions

(2015) Qi Yang et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

New low-volume resuscitation solutions containing PEG-20k

(2015) Dan Parrish et al.   Journal of Trauma and Acute Care Surgery

Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics

(2014) Johan J.F. Verhoef et al.   DRUG DISCOVERY TODAY

Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial

(2014) Nicola Longo et al.   LANCET

Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

(2014) Michael S Hershfield et al.   ARTHRITIS RESEARCH & THERAPY

Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout

(2014) Peter E Lipsky et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy and Tolerability of Pegloticase for the Treatment of Chronic Gout in Patients Refractory to Conventional Treatment

(2011)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nanoparticle PEGylation for imaging and therapy

(2011) Jesse V Jokerst et al.   Nanomedicine