Article
Chemistry, Applied
Niko S. Radulovic, Milica G. Nikolic, Marko Z. Mladenovic, Pavle Randelovic, Nikola M. Stojanovic, Zorica Stojanovic-Radic, Ljiljana Jovanovic
Summary: Inflammatory bowel diseases like Crohn's disease and their complications are a global health challenge. Pyrazole derivatives with ferrocene moieties have shown potential as new drugs, with multitarget dopamine receptor antagonists potentially being effective in treating IBM.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Ana B. Miltojevic, Katarina V. Mitic, Nikola M. Stojanovic, Pavle J. Randjelovic, Niko S. Radulovic
Summary: The study found that methyl and isopropyl N-methylanthranilates can modulate elicited macrophage functions, possibly by interfering with cell membrane function and altering the reducing cellular capacity or enzyme activity of macrophages. However, no significant inhibitory action towards xanthine oxidase or catalase was observed, indicating that the anti-inflammatory mode of action of these two esters is not related to the inhibition of these enzymes.
CHEMISTRY & BIODIVERSITY
(2022)
Review
Chemistry, Inorganic & Nuclear
Vidak Raicevic, Niko Radulovic, Marija Sakac
Summary: The medicinal chemistry of ferrocene is a rapidly growing field, with research focusing on ferrocene-steroid conjugates as targeted tools for hormone-dependent cancer cells. Attention was specifically paid to the antitumor potential testing of these conjugates.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Plant Sciences
Nikola M. Stojanovic, Marko Z. Mladenovic, Aleksandra Maslovaric, Nenad Stojiljkovic, Pavle J. Randjelovic, Niko S. Radulovic
Summary: The study examined the activity of Melissa officinalis essential oil in models simulating anxiety-related somatic symptoms and found that it could alleviate anxiety symptoms without inhibiting acetylcholinesterase activity. The results suggest that the effects of the essential oil may be related to the modification of voltage-gated Ca2+ channels or muscarinic receptors in the ileum and cardiac tissues.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Milan Dekic, Niko Radulovic, Marko Antonijevic, Dusica Dekic, Braho Licina
Summary: Clinopodium thymifolium is an aromatic plant species widely found in the Mediterranean region, used as a condiment in cooking. Chemical analysis revealed dominant compounds like pulegone, piperitone, piperitenone, and isomenthone, along with the discovery of two new natural products.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Medicinal
Sonja I. Filipovic, Nikola M. Stojanovic, Katarina V. Mitic, Pavle J. Randelovic, Niko S. Radulovic
Summary: This study found that three sesquiterpenoids from Conocephalum conicum could impact rat splenocyte viability and LDH activity, suggesting their potential as anticancer agents through affecting cell membrane function and LDH leakage/inhibition.
NATURAL PRODUCT COMMUNICATIONS
(2022)
Article
Crystallography
Niko S. Radulovic, Dragana M. Sejmanovic, Milenko N. Ristic, Vidoslav S. Dekic, Biljana Kruger, Volker Kahlenberg, Marko V. Rodic
Summary: The compound has a molecular formula of C17H14N2O3S, belongs to the monoclinic crystal system, and has specific cell parameters and crystal structure information.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2022)
Article
Plant Sciences
Bashaer Alsharif, Grace Adebusola Babington, Niko Radulovic, Fabio Boylan
Summary: The chemical composition of the essential oil obtained from the leaves of Saudi Arabian Capparis cartilaginea Decne. was analyzed, and isopropyl isothiocyanate was identified as a potential chemotaxonomical marker for this plant. The results also indicated that environmental and geographical stressors may influence the essential oil profile of plants within the genus Capparis.
Article
Green & Sustainable Science & Technology
Milan D. Kostic, Ana B. Bijelic, Olivera S. Stamenkovic, Vlada B. Veljkovic
Summary: The study investigated the production of biodiesel from used cooking oils in the presence of slaked lime catalyst and triethanolamine:menthol deep eutectic solvent. The deep eutectic solvent accelerated the transesterification reaction, following a pseudo-first-order rate law. The highest reaction rate constant was achieved using cooking oil from frying pork steaks at 60°C. The activated energy increased in the order of French fries, chicken breasts, and pork steaks.
ENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY
(2023)
Article
Chemistry, Medicinal
Nikola M. Stojanovic, Ivan Rajkovic, Vidak Raicevic, Milan N. Petkovic, Pavle J. Randjelovic, Niko S. Radulovic
Summary: This study investigated the interactions between major constituents of lemon balm essential oil and receptors using in silico modeling and in vivo experiments, and found that molecular docking could be a useful tool for screening active constituents of natural product mixtures.
NATURAL PRODUCT COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Marija S. Gencic, Nikola M. Stojanovic, Marko Z. Mladenovic, Niko S. Radulovic
Summary: L-Glutamic acid decarboxylase (GAD) is an enzyme that plays a crucial role in maintaining the balance of neurotransmitters in the brain. This study aimed to develop a method for accurately measuring GAD activity using HPLC-DAD and unpurified brain samples. The developed assay showed promising results and could potentially improve the drug development process.
NEUROCHEMISTRY INTERNATIONAL
(2022)
Article
Crystallography
Vidak Raicevic, Nikola D. Radnovic, Marko V. Rodic, Niko S. Radulovic
Summary: This paragraph describes the molecular structure and crystallographic data of 3-hydroxy-2-nitroestra-1,3,5(10)trien-17-one (2-nitroestrone).
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Biochemistry & Molecular Biology
Niko S. Radulovic, Marko Z. Mladenovic, Milan S. Dekic, Fabio Boylan
Summary: This study collected comprehensive data from NMR, MS, IR, and GC-MS on esters of different structures. A synthetic library was created, which successfully identified a new constituent in P. austriacum essential oil. The accumulated data provides chemists with a straightforward tool for future identification of related natural compounds.
Article
Plant Sciences
Marko Z. Mladenovic, Milenko N. Ristic, Andrija I. Bogdanovic, Novica R. Ristic, Fabio Boylan, Niko S. Radulovic
Summary: GC-MS analysis, synthesis, and chemical transformations were used to identify 275 constituents of Dianthus species and one Petrorhagia taxon from Serbia, including 17 completely new compounds. Multivariate statistical analysis revealed that the chemical profile of Dianthus taxa's surface waxes is influenced by both genetic and ecological factors, with ecological factors playing a more important role in the studied samples.
Article
Agriculture, Multidisciplinary
Vidak Raicevic, Marko Mladenovic, Milica Acimovic, Niko Radulovic
Summary: This study identified and analyzed volatile compounds extracted from elderflowers, discovering 252 compounds, including 115 new compounds. These findings are important for further understanding the unique scent contributions of elderflowers.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Yonghong Ye, Songyan Zheng, Yuanxing Wang
Summary: In this study, the changes of aroma components in Gannan navel orange during growth were systematically studied using HS-SPME-GC-MS. Key aroma components and markers were identified. These findings contribute to a better understanding of the dynamic variation of aroma compounds during navel orange growth and have potential for industrial applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Jia Xu, Yayuan Zhang, Mengke Zhang, Xinlin Wei, Yiming Zhou
Summary: This study evaluated the effects of glucosamine selenium on summer-autumn tea, showing that it can enhance nutritional quality, improve sensory characteristics, and increase plant adaptation to environmental changes and abiotic stresses.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yuanming Chu, Zhaoyang Ding, Jing Xie
Summary: This study investigated the use of ice glazing containing D-sodium erythorbate (DSE) and vacuum packaging to maintain the quality of large yellow croaker during frozen storage. The results showed that vacuum packaging effectively inhibited ice crystal growth and minimized water loss, while the combination of vacuum packaging and 0.3% DSE-infused ice glazing maintained freshness indicators at low levels throughout the 300-day storage period. This combination was considered the most effective in preserving the quality of the fish.
FOOD RESEARCH INTERNATIONAL
(2024)
Review
Food Science & Technology
Md. Ashikur Rahman, Shirin Akter, Md. Ashrafudoulla, Md. Anamul Hasan Chowdhury, A. G. M. Sofi Uddin Mahamud, Si Hong Park, Sang-Do Ha
Summary: This comprehensive review aims to provide insights into the mechanisms and key factors influencing biofilm formation by A. hydrophila in the food industry. It explores the molecular processes involved in various stages of biofilm formation and investigates the impact of intrinsic factors and environmental conditions on biofilm architecture and resilience. The article also highlights the potential of bibliometric analysis in conceptualizing the research landscape and identifying knowledge gaps in A. hydrophila biofilm research.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Chujing Wang, Wenni Tian, Zengliu Song, Qun Wang, Yong Cao, Jie Xiao
Summary: Solid lipid ratio in emulsions has significant effects on colloidal stability, mucus permeability, and bioavailability in vivo. Higher solid lipid ratio improves intestinal stability but reduces mucus permeability.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Dacai Zhong, Liping Kang, Juan Liu, Xiang Li, Li Zhou, Luqi Huang, Zidong Qiu
Summary: In this study, a novel online extraction electrospray ionization mass spectrometry method was developed to comprehensively characterize complex foods. Meanwhile, a characteristic marker screening method and chemometrics modeling were used for the accurate authentication of highly-similar foods. This research has significant implications for ensuring food quality and safety.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Qiannan Zhao, Jinyi Yang, Jiahui Li, Lei Zhang, Xiaohai Yan, Tianli Yue, Yahong Yuan
Summary: This study investigated the transport and hypoglycemic effects of phenolics in mulberry leaves using an in vitro digestion model. The results showed that digested phenolics had higher absorbability and could inhibit glucose digestion and absorption. Phenolics also regulated glucose metabolism. Luteoforol and p-coumaric acid were found to be the primary phenolics strongly correlated with the hypoglycemic ability of mulberry leaves.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yanyun Cao, Qingling Wang, Jinou Lin, Yin-Yi Ding, Jianzhong Han
Summary: This study investigated the effects of gallic acid (GA) and epigallocatechin gallate (EGCG) at different ratios on the gel properties of calcium induced-whey protein emulsion gel. It was found that GA and EGCG could promote gel formation, increase gel strength, and delay the release of emulsified oil droplets.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Monique Martins Strieder, Vitor Lacerda Sanches, Mauricio Ariel Rostagno
Summary: This study proposed an integrated and automated procedure for extracting, separating, and quantifying bioactive compounds from coffee co-products. By optimizing the extraction, separation, and analysis method, real-time analysis was achieved. The results suggest that coupling different techniques can efficiently extract, separate, and analyze phenolic compounds, providing an integrated method to produce high-added value ingredients for various applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Kyu Sang Sim, Hyoyoung Kim, Suel Hye Hur, Tae Woong Na, Ji Hye Lee, Ho Jin Kim
Summary: Geographical origin plays a crucial role in determining the quality and safety of agricultural products. In this study, ICP analysis was used to determine the inorganic elemental content of onions and identify their geographical origin. Chemometric methods were applied to analyze the ICP results, and the accuracy of distinguishing between Korean and Chinese onions was found to be excellent. The findings suggest that this method can be beneficial for identifying agricultural products.
FOOD RESEARCH INTERNATIONAL
(2024)
