Review
Biochemistry & Molecular Biology
Ivana Jukic, Nikolina Kolobaric, Ana Stupin, Anita Matic, Natasa Kozina, Zrinka Mihaljevic, Martina Mihalj, Petar Susnjara, Marko Stupin, Zeljka Breskic Curic, Kristina Selthofer-Relatic, Aleksandar Kibel, Anamarija Lukinac, Luka Kolar, Gordana Kralik, Zlata Kralik, Aleksandar Szechenyi, Marija Jozanovic, Olivera Galovic, Martina Medvidovic-Kosanovic, Ines Drenjancevic
Summary: Carnosine is a dipeptide synthesized in the body with beneficial antioxidant properties, mainly found in the brain, muscle, and gastrointestinal tissues. Its component beta-alanine can serve as a dietary supplement to increase muscle carnosine and improve exercise effectiveness. While widely used among athletes, carnosine is less commonly utilized in cardiovascular or diabetic patients.
Article
Environmental Sciences
Antonia Solomando, Xavier Capo, Carme Alomar, Montserrat Compa, Jose Maria Valencia, Antoni Sureda, Salud Deudero
Summary: Exposure to LDPE-MPs had significant impacts on oxidative stress and inflammation biomarkers in the liver and plasma of Sparus aurata, while no significant changes were observed in erythrocytes. During the depuration period, most of these biomarkers showed a trend of recovery and reached levels similar to those of the control group. This indicates a certain degree of reversibility in the effects of LDPE-MPs on S. aurata.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nutrition & Dietetics
Joana Erica Lima Rocha, Mariely Mendes Furtado, Renato Sampaio Mello Neto, Ana Victoria da Silva Mendes, Ana Karolinne da Silva Brito, Jose Otavio Carvalho Sena de Almeida, Emerson Iuri Rodrigues Queiroz, Jose Vinicius de Sousa Franca, Maisa Guimaraes Silva Primo, Ana Lina de Carvalho Cunha Sales, Andreanne Gomes Vasconcelos, Wanessa Felix Cabral, Selma Aparecida Souza Kuckelhaus, Jose Roberto de Souza de Almeida Leite, Ana Karina Marques Fortes Lustosa, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Maria do Carmo de Carvalho e Martins
Summary: This study evaluated the effects of fish oil supplementation on rats with hypercholesterolemia induced by a high cholesterol diet. It found that fish oil supplementation can reduce plasma and hepatic triglyceride concentrations and alleviate liver damage.
Article
Geriatrics & Gerontology
Mohammad Murtaza Mehdi, Preeti Solanki, Prabhakar Singh
Summary: Aging is defined as the result of oxidative stress affecting cells, leading to cellular dysfunction and slowing down of the system. Slowing down the aging process involves reducing the rate of cellular oxidative damage, which is related to genetic factors, lifestyle, and diet. Understanding aging theories and molecular damage caused by oxidative stress is crucial for anti-aging strategies.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2021)
Article
Chemistry, Medicinal
Marta Monteiro, Carla Sousa, Filipe Coutinho, Carolina Castro, Filipa Fontinha, Ines Guerreiro, Pedro Pousao, Elisabete Matos, Patricia Diaz-Rosales, Aires Oliva-Teles, Paula Enes, Ana Couto
Summary: The study found that marine algae extracts can reduce the physiological responses of aquaculture fish under stress conditions, improve feed efficiency, increase antioxidant enzyme activity, enhance immunity, and ultimately improve fish health.
Article
Psychiatry
Gianluca Pandolfo, Giovanni Genovese, Antonio Bruno, Domenica Campolo, Valeria Tigano, Mariateresa Cristani, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi
Summary: The pathophysiology of schizophrenia is still not well understood. Genetic factors and oxidative stress play key roles in its development and progression. Oxidative stress leads to the continuous production of oxidation products, such as AGEs and AOPPs, which interact with their receptors, amplifying the production of reactive oxygen species (ROS) and pro-inflammatory cytokines. In this study, plasma levels of AGEs and AOPPs were found to be significantly higher in schizophrenia patients compared to controls, confirming their involvement in mental disorders. Antioxidant nutraceuticals and a healthy lifestyle could reduce oxidative stress and alleviate schizophrenia symptoms.
PSYCHIATRY RESEARCH
(2022)
Article
Environmental Sciences
Oluwatosin Adetola Arojojoye, Ademola Adetokunbo Oyagbemi, Olufunke Eunice Ola-Davies, Racheal Oluwabukola Asaolu, Zainab Olabanji Shittu, Barakat Adebukola Hassan
Summary: Petroleum exploration in the Niger Delta region of Nigeria has led to contamination and destruction of the ecosystem, resulting in increased levels of oxidative stress markers and alterations in antioxidant status in fish organs. The frequency of micronucleated polychromatic erythrocytes was significantly higher in fish samples from polluted rivers compared to the control, indicating pollution mainly by oil spillage and industrial activities in these rivers.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Food Science & Technology
Concetta Maria Messina, Rosaria Arena, Giovanna Ficano, Mariano Randazzo, Maria Morghese, Laura La Barbera, Saloua Sadok, Andrea Santulli
Summary: This study demonstrates that adding antioxidants to cold-smoked meagre fillets can improve their biochemical parameters, reduce TVB-N and malondialdehyde values, thus extending the shelf life of meagre fillets.
Article
Environmental Sciences
Javad Seyedi, Mohammad Behzadi Tayemeh, Milad Esmaeilbeigi, Hamid Salari Joo, Elnaz Keshtkar Langeroudi, Ashkan Banan, Seyed Ali Johari, Mohammad Javad Jami
Summary: This research evaluated the antioxidant capability of quercetin against silver nanoparticles toxicity towards the lipid contents of ovarian, nervous, and hepatic systems as well as skeletal muscles. The findings suggest that unsaturated acyl chains, particularly HUFAs, in the liver tissue and oocyte cell are highly susceptible to peroxidation or degeneration by AgNPs. The alteration in HUFAs and PUFAs of the liver and oocyte could impact on maternal and offspring health and consequently alter long-term population dynamics of aquatic animals.
ENVIRONMENTAL RESEARCH
(2021)
Review
Agriculture, Dairy & Animal Science
Jesus Mateo Amillano-Cisneros, Maria Anel Fuentes-Valencia, Jose Belisario Leyva-Morales, Yasser A. Davizon, Henri Marquez-Pacheco, Gladys Valencia-Castaneda, Juan Antonio Maldonado-Coyac, Luz Adriana Ontiveros-Garcia, Cesar Noe Badilla-Medina
Summary: The aquaculture industry is growing rapidly and plays an essential role in meeting the increasing demand for food. The use of antibiotics in aquaculture to control bacterial diseases has led to antibiotic resistance, posing risks to the health of cultured organisms and consumers. This has spurred interest in alternative supplements such as prebiotics, which have been shown to have various beneficial effects on production and the health of aquatic animals. However, the use of these supplements is not widespread in developing countries like Mexico, highlighting the importance of promoting their use in both commercial and endemic fish cultivation.
Review
Environmental Sciences
Md Shahjahan, Md Jakiul Islam, Md Tahmeed Hossain, Moshiul Alam Mishu, Jabed Hasan, Christopher Brown
Summary: This review synthesizes currently available information about blood biomarkers used in climate change induced stress responses in fish. Specific characteristics of fish blood necessitate adapted protocols and careful interpretation of data patterns. Factors such as blood collection, handling, and storage should be considered to improve the accuracy of hematological analysis results.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Fisheries
Bruna Bitencourt Da Costa, Lis Santos Marques, Paula Graziela Lassen, Romulo Batista Rodrigues, Helen Tais Da Rosa-Silva, Jose Claudio Fonseca Moreira, Diogo Losch de Oliveira, Danilo Pedro Streit
Summary: The study aimed to investigate the effects of different concentrations of glutamine (experiment 1) and glutamine + cysteine (experiment 2) on post-thaw sperm quality of South American silver catfish. Results showed that glutamine supplementation had mixed effects on sperm quality, with increased DNA fragmentation but also higher enzyme activity. Cysteine and glutamine together did not show satisfactory results and had damaging effects on sperm quality.
AQUACULTURE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Yike Yang, Ping Xu, Fangyu Zhu, Jiujiang Liao, Yue Wu, Mingyu Hu, Huijia Fu, Juan Qiao, Li Lin, Biao Huang, Huili Jin, Xiyao Liu, Yangxi Zheng, Li Wen, Richard Saffery, Mark D. Kilby, Jianying Yan, Louise C. Kenny, Hongbo Qi, Chao Tong, Philip N. Bakerl
Summary: This study found that while MitoQ administration in late gestation could protect mice from hypertension and kidney damage induced by RUPP, it exacerbated the PE phenotype when given in early gestation, indicating the necessity of mild oxidative stress for trophoblast proliferation, invasion, and migration.
ANTIOXIDANTS & REDOX SIGNALING
(2021)
Article
Environmental Sciences
Mahmoud A. O. Dawood, Ahmed E. Noreldin, Hani Sewilam
Summary: This study investigated the impact of varying levels of water salinity on the growth performance, survival rate, and blood biochemistry of African catfish. The results showed that high salinity hindered the growth performance and health status of the fish, while heat stress improved the antioxidative status.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Owias Iqbal Dar, Raouf Aslam, Sunil Sharma, Ai-Qun Jia, Arvinder Kaur, Caterina Faggio
Summary: This study investigated the effects of triclosan on fish embryos and found that it can alter the free amino acids and protein structures of fish, leading to changes in their secondary structures.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2022)
Article
Ecology
Simone Messina, David P. Edwards, Valeria Marasco, Virginie Canoine, Cindy C. P. Cosset, Suzanne Tomassi, Suzan Benedick, Marcel Eens, David Costantini
FUNCTIONAL ECOLOGY
(2020)
Article
Biodiversity Conservation
Daniele Canestrelli, Roberta Bisconti, Anita Liparoto, Frederic Angelier, Cecile Ribout, Claudio Carere, David Costantini
Article
Biology
Valeria Marasco, Manrico Sebastiano, David Costantini, Gianni Pola, Leonida Fusani
Summary: The emergence of the migratory phenotype in birds is associated with changes in oxidative status, including higher levels of TBARS in the liver, lower levels of SOD in red blood cells and liver, and higher levels of GPx in the pectoral muscle. Despite higher food intake in migratory birds, there is no link between food intake and markers of oxidative status. The increase in body mass is positively correlated with muscle GPx activity during pre-migratory fattening, suggesting strategic displacement of oxidative costs to safeguard muscles for successful migration.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Environmental Sciences
Pamela Trisolino, Alcide di Sarra, Damiano Sferlazzo, Salvatore Piacentino, Francesco Monteleone, Tatiana Di Iorio, Francesco Apadula, Daniela Heltai, Andrea Lanza, Antonio Vocino, Luigi Caracciolo di Torchiarolo, Paolo Bonasoni, Francescopiero Calzolari, Maurizio Busetto, Paolo Cristofanelli
Summary: The study developed a data selection algorithm to identify background atmospheric CO2 observations from in situ continuous measurements, effectively separating local/regional signals from background signals. Through testing and optimization at four Italian stations with different environmental conditions, the algorithm's effectiveness and specific applications were determined, with a discussion on possible uses for the screened data.
Article
Physiology
David Costantini, Shelly Masi, Lyna Rachid, Marielle Beltrame, Melanie Rohmer, Sabrina Krief
Summary: This study investigated the impact of dietary antioxidants on oxidative status in chimpanzees. The results showed that a decrease in dietary antioxidants increased oxidative damages, while an increase had no effect. Older and higher-ranking chimpanzees had lower levels of oxidative damage, suggesting individual factors play a role in oxidative status.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2021)
Article
Environmental Sciences
Marion Cheron, David Costantini, Frederic Angelier, Cecile Ribout, Francois Brischoux
Summary: This study investigated the impact of AMPA on tadpole embryonic development, finding non-monotonic effects on oxidative status markers and suggesting that oxidative imbalance may lead to reduced hatching success.
Article
Zoology
Roberta Bisconti, Claudio Carere, David Costantini, Anita Liparoto, Andrea Chiocchio, Daniele Canestrelli
Summary: Recent studies have shown that personality and locomotory performance traits are important for dispersal syndromes and can evolve during range expansions and colonization. However, little is known about the effects of island colonization on these traits and how they contribute to colonization. In this study, we investigated the contribution of island colonization triggered by postglacial range expansions to intraspecific variation in personality and locomotory performance traits in the Tyrrhenian tree frog. We found that individuals from the recently colonized island were bolder, while individuals from the main island showed higher jumping and stickiness performance.
Article
Engineering, Environmental
Evgenios Agathokleous, Damia Barcelo, Michael Aschner, Ricardo Antunes Azevedo, Prosun Bhattacharya, David Costantini, G. Christopher Cutler, Alessandra De Marco, Anca Oana Docea, Jose G. Dorea, Stephen O. Duke, Thomas Efferth, Despo Fatta-Kassinos, Vasileios Fotopoulos, Antonio Ginebreda, Raul Narciso C. Guedes, A. . Wallace Hayes, Ivo Iavicoli, Olga-Ioanna Kalantzi, Takayoshi Koike, Demetrios Kouretas, Manish Kumar, Jose E. Manautou, Michael N. Moore, Elena Paoletti, Josep Penuelas, Yolanda Pico, Russel J. Reiter, Ramin Rezaee, Jorg Rinklebe, Teresa Rocha-Santos, Pierre Sicard, Christian Sonne, Christopher Teaf, Aristidis Tsatsakis, Alexander I. . Vardavas, Wenjie Wang, Eddy Y. Zeng, Edward J. Calabrese
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Physiology
Heiko G. Rodel, Veridiana Jardim, Marylin Rangassamy, Ludivine Jaravel, Daphne Jacquet, Raquel Monclus, Christophe Feron, David Costantini
Summary: It is increasingly recognized that alterations of the cellular oxidative status might be an important cost underlying challenging early life conditions. This study investigated the long-term consequences of early life parameters on the oxidative status in mature mice, and found complex interactions between early life conditions, personality, and oxidative status.
PHYSIOLOGICAL REPORTS
(2022)
Article
Environmental Sciences
C. Fratticioli, P. Trisolino, M. Maione, F. Calzolari, C. Calidonna, D. Biron, S. Amendola, M. Steinbacher, P. Cristofanelli
Summary: The aim of this research was to estimate anthropogenic CH4 emissions in the Po basin from 2015 to 2019 using an inter-species correlation approach. The results showed lower emissions compared to existing bottom-up inventories, but an increasing tendency in CH4 emissions over the study period based on atmospheric observations. The study also identified challenges related to the methodology and emphasized the importance of careful consideration of input data for integrating CH4 bottom-up inventories.
ENVIRONMENTAL RESEARCH
(2023)
Article
Ecology
Maria Cristina Lorenzi, Franco G. Robles-Guerrero, David Costantini
Summary: Measuring reproductive costs is crucial to understanding sexual conflict and its evolutionary outcomes. In this study, hermaphroditic worms were exposed to different social conditions to measure reproductive costs. It was found that hermaphrodites that invested relatively more in the female function produced fewer eggs but had higher levels of antioxidant protection. This suggests that in the short-term, male competition might be costlier than egg production in terms of regulation of oxidative status.
Article
Multidisciplinary Sciences
Armando Macali, Sara Ferretti, Serena Scozzafava, Claudio Carere
Summary: Biotic conflict drives evolutionary competition among species for vital populations. Intraspecific conflict is a significant selective force in high-density non-indigenous populations, as cannibals enhance their survival by killing and feeding on competitors. This study reports on the strong propensity for cannibalism and cerata autotomy in the invasive Mediterranean population of the nudibranch Godiva quadricolor. Additionally, it presents fourteen cases of self-cannibalism in captivity, making it one of the most notable records of this uncommon behavior to date. The observations are discussed within the context of behavioral traits associated with non-indigenous populations and biological invasions.
RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI
(2023)
Article
Multidisciplinary Sciences
Rolf F. Storms, Claudio Carere, Robert Musters, Hans van Gasteren, Simon Verhulst, Charlotte K. Hemelrijk
Summary: Collisions between birds and airplanes result in significant financial losses for the international civil aviation industry annually. The effectiveness of current deterrence methods is limited. Researchers have developed a RobotFalcon, inspired by the peregrine falcon, to scare away bird flocks. The RobotFalcon outperformed a drone and traditional methods in effectively deterring birds.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Article
Biochemistry & Molecular Biology
Sang Hyuck Lee, Mi Ae Kim, Young Chang Sohn
Summary: This study characterized the CCAP signaling system in Pacific abalone and revealed its relationship with the calcium/PKC and cAMP/PKA signal transduction pathways. It provides new insights into the evolutionary origins of the NPS and OT/VP signaling systems in protostomes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Hanna Scheuffele, Erica V. Todd, John A. Donald, Timothy D. Clark
Summary: Global warming is causing an increase in extreme weather events, affecting ecosystems and the behavior of ectotherms. More research is needed to understand the impact of diurnal thermal variability and improve climate change predictions.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jaakko Haverinen, Ahmed Badr, Markus Eskelinen, Matti Vornanen
Summary: The acclimatization of certain ectothermic vertebrates to winter conditions involves reduced energy consumption, achieved through decreased movement activity, depression of cellular functions, or switching to anaerobic energy production. This study on crucian carp showed that winter-acclimatized fish exhibited lower metabolic rates and a shift to anaerobic energy production during anoxia. Winter dormancy in crucian carp is achieved through active reduction of energy consumption, a slowed metabolic rate, and a direct response to oxygen absence.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Maria Cruz Sueiro, Cynthia A. Awruch, Gustavo M. Somoza, Walter S. Svagelj, Maria G. Palacios
Summary: According to life-history theory, there might be different immunological strategies between reproductive and non-reproductive periods due to limited resources. Our study on two sympatric marine fish species, rockfish and sandperch, found that reproductive individuals showed lower immune function, but higher levels of natural antibodies in rockfish females, compared to their non-reproductive counterparts. On the other hand, reproductively active sandperch males showed lower levels of natural antibodies and higher neutrophil to lymphocyte ratio and spleen index compared to non-reproductive males. The study highlights the species-specific patterns of immunity and the potential influence of resource limitation and abiotic factors on immune trade-offs in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
James B. Cummins, Dane A. Crossley II
Summary: This study focuses on cardiovascular development in altricial bird species, which has been less studied compared to precocial species. The researchers investigated the cholinergic and adrenergic receptor mediated control of arterial blood pressure and heart rate in the neotropic cormorant. The findings suggest that both cholinergic and adrenergic tone play a role in cardiovascular regulation in embryonic birds.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ru Xia, Hong-Kang Liu, Xi-Feng Liu, Xin Deng, Chuan-Jie Qin, Yuan-Fa He, Shi-Mei Lin, Yong-Jun Chen
Summary: This study cloned the genes encoding glucokinase and glucose-6-phosphatase catalytic subunit in largemouth bass, revealing their distribution and transcriptional regulation. The results showed that the functions of G6pc and Gck in LMB were highly conserved in evolution, and the interconversion of glucose and G6P in the liver was well regulated at the transcript level under high starch diet, but a futile cycle was induced after a glucose load.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2024)