Tuning chemoselectivity in O-/N-arylation of 3-aryl-1,2,4-oxadiazolones with ortho-(trimethylsilyl)phenyl triflates via aryne insertion

Hypervalent Iodine/Triflate Hybrid Benzdiyne Equivalents: Access to Controlled Synthesis of Polycyclic Aromatic Compounds

(2017) Tsugio Kitamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Aryne Formation via Grob Fragmentation from the [2+2] Cycloadducts of 3-Triflyloxyarynes

(2017) Jiarong Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tf2NH-catalyzed formal [3 + 2] cycloaddition of oxadiazolones with ynamides: a simple access to aminoimidazoles

(2017) Yingying Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Selective Synthesis of Dihydrobenzo[d]isoxazoles and Dihydrobenzo[d]oxazoles from Oximes and Arynes via in Situ Generation of Nitrones

(2017) Tuanli Yao et al.   ORGANIC LETTERS

Employing Arynes in Diels–Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions

(2016) Sachin Suresh Bhojgude et al.   ACCOUNTS OF CHEMICAL RESEARCH

Metal Free Bi(hetero)aryl Synthesis: A Benzyne Truce-Smiles Rearrangement

(2016) Catherine M. Holden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trapping σ-Alkyl-Palladium(II) Intermediates with Arynes Encompassing Intramolecular C−H Activation: Spirobiaryls through Pd-Catalyzed Cascade Reactions

(2016) Marta Pérez-Gómez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From insertion to multicomponent coupling: temperature dependent reactions of arynes with aliphatic alcohols

(2016) Manikandan Thangaraj et al.   CHEMICAL COMMUNICATIONS

Quantification of the Electrophilicity of Benzyne and Related Intermediates

(2016) Noah F. Fine Nathel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Free Coupling Annulation of Arynes with Ketones and Alkynoates: Assembly of Functionalized Naphthalenes

(2016) Wen-Ming Shu et al.   ORGANIC LETTERS

Aryne-Mediated [2,3]-Sigmatropic Rearrangement of Tertiary Allylic Amines

(2016) Juan Zhang et al.   ORGANIC LETTERS

Diamination of Domino Aryne Precursor with Sulfonamides

(2016) Dachuan Qiu et al.   ORGANIC LETTERS

Synthesis of Aryl Ketoamides via Aryne Insertion into Imides

(2016) Austin C. Wright et al.   ORGANIC LETTERS

Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides

(2016) Shreesha V Bhat et al.   ORGANIC LETTERS

Oxadiazolone-Enabled Synthesis of Primary Azaaromatic Amines

(2016) Xiaolong Yu et al.   ORGANIC LETTERS

Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis through CH Activation and Orthogonal Reactivity

(2015) Emilien Demory et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diphenyliodonium-Catalyzed Fluorination of Arynes: Synthesis ofortho-Fluoroiodoarenes

(2015) Yuwen Zeng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Domino Aryne Precursor: Efficient Construction of 2,4-Disubstituted Benzothiazoles

(2015) Jiarong Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N-Arylation

(2015) Suguru Yoshida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicomponent Coupling Cyclization Access to Cinnolines via in Situ Generated Diazene with Arynes, and α-Bromo Ketones

(2015) Wen-Ming Shu et al.   ORGANIC LETTERS

Activation of Aryl Thiocyanates Followed by Aryne Insertion: Access to 1,2-Thiobenzonitriles

(2015) Martin Pawliczek et al.   ORGANIC LETTERS

Stereoselective [3+2] cycloaddition of N-tert-butanesulfinyl imines to arynes facilitated by a removable PhSO2CF2 group: synthesis and transformation of cyclic sulfoximines

(2014) Wenchao Ye et al.   CHEMICAL COMMUNICATIONS

Three-Component Coupling Reaction Triggered by Insertion of Arynes into the S═O Bond of DMSO

(2014) Feng-Lei Liu et al.   ORGANIC LETTERS

Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles, and Isatins

(2013) Anup Bhunia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heteroannulation of arynes with N-aryl-α-aminoketones for the synthesis of unsymmetrical N-aryl-2,3-disubstituted indoles: an aryne twist of Bischler–Möhlau indole synthesis

(2013) Ala Bunescu et al.   CHEMICAL COMMUNICATIONS

Silver-Mediated Trifluoromethylation–Iodination of Arynes

(2013) Yuwen Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reaction of Arynes with Vinylogous Amides: Nucleophilic Addition to the ortho-Quinodimethide Intermediate

(2013) Ran Li et al.   ORGANIC LETTERS

Insertion of Arynes into Arylphosphoryl Amide Bonds: One-Step Simultaneous Construction of C–N and C–P Bonds

(2013) Chaoren Shen et al.   ORGANIC LETTERS

Arynes and Cyclohexyne in Natural Product Synthesis

(2012) Christian M. Gampe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Comprehensive History of Arynes in Natural Product Total Synthesis

(2012) Pamela M. Tadross et al.   CHEMICAL REVIEWS

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

(2012) Adam E. Goetz et al.   Nature Chemistry

Use of benzynes for the synthesis of heterocycles

(2012) Anton V. Dubrovskiy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nucleophilic addition to 2,3-pyridyne and synthesis of benzonaphthyridinones

(2012) Yuesi Fang et al.   TETRAHEDRON

Transition-Metal-Free Direct Arylation of Anilines

(2011) Tracey Pirali et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver Triflate Catalyzed Reaction of 2-Alkynylbenzaldoxime with Aryne

(2011) Hui Ren et al.   ORGANIC LETTERS

Synthetic Methods for the Generation and Preparative Application of Benzyne

(2010) Tsugio Kitamura   AUSTRALIAN JOURNAL OF CHEMISTRY

Generation of benzyne from benzoic acid using C–H activation

(2010) Alastair A. Cant et al.   CHEMICAL COMMUNICATIONS

Insertion of Benzene Rings into the Amide Bond: One-Step Synthesis of Acridines and Acridones from Aryl Amides

(2009) Didier G. Pintori et al.   ORGANIC LETTERS

Fluorenes as new molecular scaffolds for carbon–carbon σ-bond cleavage reaction: acylfluorenylation of arynes

(2008) Hiroto Yoshida et al.   CHEMICAL COMMUNICATIONS