Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids
出版年份 2018 全文链接
标题
Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids
作者
关键词
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出版物
CHEMBIOCHEM
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-06-21
DOI
10.1002/cbic.201800170
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery
- (2016) Thomas G. Davies et al. JOURNAL OF MEDICINAL CHEMISTRY
- A systematic molecular dynamics approach to the study of peptide Keap1–Nrf2 protein–protein interaction inhibitors and its application to p62 peptides
- (2016) Meng-Chen Lu et al. Molecular BioSystems
- Peptide and small molecule inhibitors of the Keap1–Nrf2 protein–protein interaction
- (2015) Geoff Wells BIOCHEMICAL SOCIETY TRANSACTIONS
- Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators
- (2015) Atul D. Jain et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
- (2015) Lauren E. Tebay et al. FREE RADICAL BIOLOGY AND MEDICINE
- Binding of Disordered Peptides to Kelch: Insights from Enhanced Sampling Simulations
- (2015) Trang Nhu Do et al. Journal of Chemical Theory and Computation
- Structure–Activity and Structure–Property Relationship and Exploratory in Vivo Evaluation of the Nanomolar Keap1–Nrf2 Protein–Protein Interaction Inhibitor
- (2015) Zheng-Yu Jiang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1–Nrf2 Protein–Protein Interaction
- (2015) Hélène C. Bertrand et al. JOURNAL OF MEDICINAL CHEMISTRY
- PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy
- (2014) Daniel A. East et al. CHEMISTRY & BIOLOGY
- Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis
- (2014) Zheng-Yu Jiang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal-contact engineering to obtain a crystal form of the Kelch domain of human Keap1 suitable for ligand-soaking experiments
- (2013) Stefan Hörer et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction
- (2013) Longqin Hu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1
- (2013) Toshiaki Fukutomi et al. MOLECULAR AND CELLULAR BIOLOGY
- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction with improved binding and cellular activity
- (2013) Rowena Hancock et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
- (2013) L. Baird et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward clinical application of the Keap1–Nrf2 pathway
- (2013) Takafumi Suzuki et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction
- (2012) Richard Steel et al. ACS Medicinal Chemistry Letters
- The cytoprotective role of the Keap1–Nrf2 pathway
- (2011) Liam Baird et al. ARCHIVES OF TOXICOLOGY
- Kinetic Analyses of Keap1-Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance
- (2011) Yu Chen et al. Chemical Biology & Drug Design
- Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction
- (2011) Rowena Hancock et al. FREE RADICAL BIOLOGY AND MEDICINE
- Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides
- (2010) Amit Choudhary et al. AMINO ACIDS
- NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
- (2009) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Structural analysis of the complex of Keap1 with a prothymosin α peptide
- (2008) Balasundaram Padmanabhan et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
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