Drosophila Hsp67Bc hot-spot variants alter muscle structure and function

Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance

(2015) I. Wojtowicz et al.   DEVELOPMENT

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

(2014) Serena Carra et al.   Autophagy

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Contribution of small heat shock proteins to muscle development and function

(2014) Magda Dubińska-Magiera et al.   FEBS LETTERS

Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies

(2013) M. Sandri et al.   JOURNAL OF CELL SCIENCE

Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients

(2012) Joy Irobi et al.   NEUROMUSCULAR DISORDERS

Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases from Yeast and Humans

(2012) Martin L. Duennwald et al.   PLOS BIOLOGY

Dysregulation of axonal transport and motorneuron diseases

(2011) Daniela Sau et al.   BIOLOGY OF THE CELL

HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes

(2011) Alice S. Kwok et al.   JOURNAL OF NEUROCHEMISTRY

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases

(2011) K. Seidel et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Large Potentials of Small Heat Shock Proteins

(2011) Evgeny V. Mymrikov et al.   PHYSIOLOGICAL REVIEWS

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins

(2011) Serena Carra et al.   PROGRESS IN NEUROBIOLOGY

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

(2010) Valeria Crippa et al.   Autophagy

Manipulation of Death Pathways in Desmin-Related Cardiomyopathy

(2010) Alina Maloyan et al.   CIRCULATION RESEARCH

Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

(2010) Verena Arndt et al.   CURRENT BIOLOGY

Mutant HSPB8 causes motor neuron-specific neurite degeneration

(2010) Joy Irobi et al.   HUMAN MOLECULAR GENETICS

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

(2010) Valeria Crippa et al.   HUMAN MOLECULAR GENETICS

Identification of theDrosophilaOrtholog of HSPB8

(2010) Serena Carra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heat shock proteins: Cellular and molecular mechanisms in the central nervous system

(2010) R. Anne Stetler et al.   PROGRESS IN NEUROBIOLOGY

The stress-inducible HspB8-Bag3 complex induces the eIF2α kinase pathway: Implications for protein quality control and viral factory degradation?

(2009) Serena Carra   Autophagy

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

The pivotal role of the β7 strand in the intersubunit contacts of different human small heat shock proteins

(2009) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease

(2009) Lev G. Goldfarb et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation in BAG3 causes severe dominant childhood muscular dystrophy

(2008) Duygu Selcen et al.   ANNALS OF NEUROLOGY

Structural and Functional Diversities between Members of the Human HSPB, HSPH, HSPA, and DNAJ Chaperone Families†

(2008) Michel J. Vos et al.   BIOCHEMISTRY

Autophagy is an adaptive response in desmin-related cardiomyopathy

(2008) P. Tannous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA