Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z

dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity

(2015) Wing-Cheong Wong et al.   Biology Direct

HMMER web server: 2015 update

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation

(2014) Wing-Cheong Wong et al.   BMC BIOINFORMATICS

Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein’s omega-site and the GPI lipid anchor’s phosphoethanolamine

(2014) Birgit Eisenhaber et al.   CELL CYCLE

Complementation of Essential Yeast GPI Mannosyltransferase Mutations Suggests a Novel Specificity for Certain Trypanosoma and Plasmodium PigB Proteins

(2014) Leslie K. Cortes et al.   PLoS One

GPI Transamidase and GPI anchored proteins: Oncogenes and biomarkers for cancer

(2013) Dilani G. Gamage et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Transmembrane helix: simple or complex

(2012) Wing-Cheong Wong et al.   NUCLEIC ACIDS RESEARCH

A DECADE AFTER THE FIRST FULL HUMAN GENOME SEQUENCING: WHEN WILL WE UNDERSTAND OUR OWN GENOME?

(2012) FRANK EISENHABER   Journal of Bioinformatics and Computational Biology

Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins

(2011) Wing-Cheong Wong et al.   Biology Direct

Analysis of Membrane Topology and Identification of Essential Residues for the Yeast Endoplasmic Reticulum Inositol Acyltransferase Gwt1p

(2011) Koji Sagane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

More Than 1,001 Problems with Protein Domain Databases: Transmembrane Regions, Signal Peptides and the Issue of Sequence Homology

(2010) Wing-Cheong Wong et al.   PLoS Computational Biology

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Profiling the expression pattern of GPI transamidase complex subunits in human cancer

(2008) Jatin K Nagpal et al.   MODERN PATHOLOGY