Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein’s omega-site and the GPI lipid anchor’s phosphoethanolamine

Low-resolution structure of the soluble domain GPAA1 (yGPAA170–247) of the glycosylphosphatidylinositol transamidase subunit GPAA1 fromSaccharomyces cerevisiae

(2013) Wuan Geok Saw et al.   BIOSCIENCE REPORTS

Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis

(2013) Li Chen et al.   BMC GENOMICS

Sortase A-mediated chemoenzymatic synthesis of complex glycosylphosphatidylinositol-anchored protein

(2013) Zhimeng Wu et al.   CHEMICAL COMMUNICATIONS

GPI Transamidase and GPI anchored proteins: Oncogenes and biomarkers for cancer

(2013) Dilani G. Gamage et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2013) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs

(2012) Birgit Koch et al.   BIOCHEMISTRY

Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico-Modeling/Site-Directed Mutagenesis Approach: Implications for Drug Development

(2012) Birgit Koch et al.   Chemical Biology & Drug Design

Transmembrane helix: simple or complex

(2012) Wing-Cheong Wong et al.   NUCLEIC ACIDS RESEARCH

A DECADE AFTER THE FIRST FULL HUMAN GENOME SEQUENCING: WHEN WILL WE UNDERSTAND OUR OWN GENOME?

(2012) FRANK EISENHABER   Journal of Bioinformatics and Computational Biology

Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center

(2011) David Ruiz-Carrillo et al.   BIOCHEMISTRY

Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins

(2011) Wing-Cheong Wong et al.   Biology Direct

Structural insight into the glycosylphosphatidylinositol transamidase subunits PIG-K and PIG-S from yeast

(2010) Yew Kwang Toh et al.   JOURNAL OF STRUCTURAL BIOLOGY

More Than 1,001 Problems with Protein Domain Databases: Transmembrane Regions, Signal Peptides and the Issue of Sequence Homology

(2010) Wing-Cheong Wong et al.   PLoS Computational Biology

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

ANNIE: integrated de novo protein sequence annotation

(2009) H. S. Ooi et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate automatic structure prediction with HHpred

(2009) Andrea Hildebrand et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins†

(2008) Margot G. Paulick et al.   BIOCHEMISTRY

PSI-BLAST pseudocounts and the minimum description length principle

(2008) Stephen F. Altschul et al.   NUCLEIC ACIDS RESEARCH