A head-to-tail view of L-selectin and its impact on neutrophil behaviour

The cytoplasmic tail of L-selectin interacts with the adaptor-protein complex AP-1 subunit μ1A via a novel basic binding motif

(2017) Karim Dib et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

L-selectin mechanochemistry restricts neutrophil priming in vivo

(2017) Zhenghui Liu et al.   Nature Communications

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force

(2016) Padmaja Mehta-D'souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Formyl peptides drive mitochondrial damage associated molecular pattern induced neutrophil activation through ERK1/2 and P38 MAP kinase signalling pathways

(2015) Jon Hazeldine et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Neutrophil ageing is regulated by the microbiome

(2015) Dachuan Zhang et al.   NATURE

Leukocyte Migration into Inflamed Tissues

(2014) Sussan Nourshargh et al.   IMMUNITY

Blood Vessels Pattern Heparan Sulfate Gradients between Their Apical and Basolateral Aspects

(2014) Liat Stoler-Barak et al.   PLoS One

Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance

(2013) María Casanova-Acebes et al.   CELL

Over-sulfated glycosaminoglycans are alternative selectin ligands: insights into molecular interactions and possible role in breast cancer metastasis

(2013) Pierre Martinez et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Drosophila Selectin Furrowed Mediates Intercellular Planar Cell Polarity Interactions via Frizzled Stabilization

(2013) Mei-Ling Chin et al.   DEVELOPMENTAL CELL

Signals regulating L-selectin-dependent leucocyte adhesion and transmigration

(2013) Aleksandar Ivetic   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Transient PKC  shuttling to the immunological synapse is governed by DGK  and regulates L-selectin shedding

(2013) S. I. Gharbi et al.   JOURNAL OF CELL SCIENCE

The PSGL-1–L-selectin signaling complex regulates neutrophil adhesion under flow

(2013) Anika Stadtmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Surface Expression of ADAM10 and ADAM17 on Human T Lymphocytes and Tumor Cells

(2013) Henriette Ebsen et al.   PLoS One

Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes

(2013) Nandini Mondal et al.   Cell Adhesion & Migration

Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism

(2013) Yolanda Pérez et al.   Scientific Reports

Regulation of Neutrophil Function by Adenosine

(2012) Kathryn E. Barletta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils

(2012) Maria Domínguez-Luis et al.   BIOCHEMICAL PHARMACOLOGY

Silencing α1,3-Fucosyltransferases in Human Leukocytes Reveals a Role for FUT9 Enzyme during E-selectin-mediated Cell Adhesion

(2012) Alexander Buffone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into Calmodulin-regulated L-selectin Ectodomain Shedding

(2012) Jessica L. Gifford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycodelin-A Stimulates Interleukin-6 Secretion by Human Monocytes and Macrophages through L-selectin and the Extracellular Signal-regulated Kinase Pathway

(2012) Cheuk-Lun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

(2012) Doris Proebstl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signaling through L-Selectin Mediates Enhanced Chemotaxis of Lymphocyte Subsets to Secondary Lymphoid Tissue Chemokine

(2012) H. Subramanian et al.   JOURNAL OF IMMUNOLOGY

ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment

(2012) C. Long et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Learning in motion: pericytes instruct migrating innate leukocytes

(2012) Ronen Alon et al.   NATURE IMMUNOLOGY

Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

(2011) J. Tang et al.   BLOOD

l-Selectin – A dynamic regulator of leukocyte migration

(2011) Stefanie Wedepohl et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Interaction of Calmodulin with l-Selectin at the Membrane Interface: Implication on the Regulation of l-Selectin Shedding

(2011) Wei Deng et al.   JOURNAL OF MOLECULAR BIOLOGY

The association of L-selectin polymorphisms with L-selectin serum levels and risk of ischemic stroke

(2011) Ye-Sheng Wei et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Architecture effects on L-selectin shedding induced by polypeptide-based multivalent ligands

(2011) Shuang Liu et al.   Polymer Chemistry

Cross-domain inhibition of TACE ectodomain

(2011) C. J. Tape et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cytoplasmic domains of TNFα-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding

(2010) David J. Killock et al.   BIOCHEMICAL JOURNAL

E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin  L 2-mediated slow leukocyte rolling

(2010) T. Yago et al.   BLOOD

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC)  2 and PI3K  pathways

(2010) H. Mueller et al.   BLOOD

Heparan sulfate proteoglycans in extravasation: assisting leukocyte guidance

(2010) Johanna et al.   Frontiers in Bioscience-Landmark

Molecular Cloning and Expression Analysis of P-Selectin from Zebrafish (Danio rerio)

(2010) Guijin Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Transmembrane Domains of L-selectin and CD44 Regulate Receptor Cell Surface Positioning and Leukocyte Adhesion under Flow

(2010) Konrad Buscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LFA-1 and Mac-1 Define Characteristically Different Intralumenal Crawling and Emigration Patterns for Monocytes and Neutrophils In Situ

(2010) R. Sumagin et al.   JOURNAL OF IMMUNOLOGY

In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli -mediated peritonitis

(2010) Chunmei Long et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In Vitroandin VivoCharacterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin

(2009) David J. Killock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

L-selectin ligation-induced CSF-1 gene transcription is regulated by AP-1 in a c-Abl kinase-dependent manner

(2008) Cuixia Chen et al.   HUMAN IMMUNOLOGY

Dermatan sulfate proteoglycan biglycan as a potential selectin L/CD44 ligand involved in selective recruitment of peripheral blood CD16(−) natural killer cells into human endometrium

(2008) Kotaro Kitaya et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Critical role of Lck in L-selectin signaling induced by sulfatides engagement

(2008) Ting Xu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Enrichment of Distinct Microfilament-Associated and GTP-Binding-Proteins in Membrane/Microvilli Fractions from Lymphoid Cells

(2008) Jian-Jiang Hao et al.   JOURNAL OF PROTEOME RESEARCH