Article
Chemistry, Applied
Yuting Fan, Tao Tao, Huijun Wang, Zeyu Liu, Wei Huang, Hui Cao
Summary: This study presents a new sensor design mediated by graphene quantum dots for fast and effective detection of picric acid in water and air, showing higher fluorescent quantum yield and better selective detection capability. Luminescent Schiff-GQDs exhibit significant quenching effects, lower detection limits, and the ability to detect PA with the naked eye.
Article
Materials Science, Multidisciplinary
Yu Ma, Yan Liu, Yurui Wang, Yanzhu Guo, Yuanyuan Li, Ruizhi Li, Xinzi Kong, Qize Han, Rong Wei, Jing Wang
Summary: The study utilized graphene quantum dots as a vehicle to deliver evodiamine, which significantly inhibited the growth of oral squamous cell carcinoma cells in nude mice, providing a new approach for the treatment of OSCC.
MATERIALS & DESIGN
(2022)
Article
Physics, Applied
Shuning Wang, Maojun Zheng, Dongkai Jiang, Hao Yuan, Hao Chen, Yunlong Fan, Fanggang Li, Wenlan Zhang, Li Ma, Wenzhong Shen
Summary: Zinc oxide (ZnO) is a promising UV detector material with advantages of wide bandgap, rich resources, simple preparation, and environmental friendliness. However, its complicated preparation processes and complex device structures have limited its application. In this study, a high-performance UV detector based on graphene quantum dot-sensitized GaP@ZnO nanocomposite was successfully fabricated using a simple spin-coating method. This research provides a new method for preparing high-performance optoelectronic devices using material composites and surface modification.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Nanoscience & Nanotechnology
Poonkuzhali Kaliyaperumal, Seenivasagan Renganathan, Karthika Arumugam, Bukola Rhoda Aremu
Summary: This study introduces a novel inhibitor that can inhibit the aggregation of alpha-synuclein and potentially treat Parkinson's disease. By functionally engineering compounds and nanomaterials, this inhibitor demonstrates promising results both in vitro and in vivo, highlighting its potential as a therapeutic candidate for Parkinson's disease.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Nasrin Vahedi, Fatemeh Tabandeh, Matin Mahmoudifard
Summary: The study highlighted the use of graphene quantum dots as drug carriers and imaging agents for cancer cells, with hyaluronic acid decoration for targeted delivery. The synthesized nanocarrier showed complete biocompatibility and reduced cell viability through hyaluronic acid-mediated drug cell uptake. Fluorescent microscopy confirmed the adsorption of these nanocarriers on cancer cells, as opposed to normal cells.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Sara Samuei, Zolfaghar Rezvani, Ashkan Shomali, Emine Ulker, Ferdi Karadas
Summary: A new composite material of graphene quantum dots and NiFe layered double hydroxide was successfully prepared and characterized in terms of structure, composition, and morphology. The material exhibited excellent electrochemical properties with high specific capacitance and long cycle life, making it a promising candidate for use in supercapacitors. This study provides a valuable method for the preparation of novel nanocomposites for energy storage and conversion applications.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Engineering, Environmental
Siew Fen Chua, Alireza Nouri, Ebrahim Mahmoudi, Wei Lun Ang, Abdul Wahab Mohammad
Summary: Nitrogen-doped graphene quantum dot (NGQD) was used to enhance the surface chemistry and cross-linking degree in thin film nanocomposite (TFN) membrane for wastewater treatment. The incorporation of NGQD increased the hydrophilicity and surface roughness of TFN membranes, resulting in improved water permeability. Additionally, NGQD enhanced the rejection of divalent salt and improved the antifouling properties of the membrane. The minimal incorporation of NGQD increased the PA cross-linking degree and surface negativity, preventing the deposition of pollutants on the membrane surface.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Nanoscience & Nanotechnology
Elif Orhan, Aslihan Anter, Murat Ulusoy, Baris Polat, Can Okuyucu, Mustafa Yildiz, Semsettin Altindal
Summary: Carbon, especially graphene quantum dots (GQDs) based electronics, have gained attention as a promising technology. Modifying the electrical and optoelectronic properties of GQDs through physical/chemical processes or synthetic methods may open up new applications. In this study, gadolinium-doped polyethyleneimine (PEI) functionalized and nitrogen-doped graphene quantum dots (GdNPs-PEI@N-GQDs) were synthesized by a hydrothermal method to investigate how doping carbon-based materials with Gd affects their electrical properties. The electrical properties of the GdNPs/PEI@N-GQDs nanocomposite-based diode were analyzed using current-voltage (I-V) and capacitance and conductance voltage (C-V & G/ω-V) techniques. The study found that the diode exhibited rectification behavior with a rectification ratio (RR) of 14 at ±5V. However, after doping with Gd, the diode showed ohmic behavior with a rectification ratio of 2.8 x 10(4) at ±5V. These findings have implications for the advancement of carbon-based electronics technology.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Elizabeth Campbell, Md Tanvir Hasan, Roberto Gonzalez-Rodriguez, Tate Truly, Bong Han Lee, Kayla N. Green, Giridhar Akkaraju, Anton V. Naumov
Summary: This study developed a new multifunctional biocompatible anticancer nanoformulation that provides targeted image-guided cancer therapy, demonstrating capabilities in treatment, imaging, and specific targeting of cancer cells.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Adriana Zelenakova, Jaroslava Szucsova, Lubos Nagy, Vladimir Girman, Vladimir Zelenak, Veronika Huntosova
Summary: In this study, a drug delivery composite (DDC) consisting of ordered mesoporous silica, iron oxide magnetic nanoparticles (Fe2O3), and the drug naproxen (Napro) was prepared. The results reveal the suppression of the Brownian relaxation process and indicate the potential application of the composite as a drug nanocarrier for magnetic-targeted drug delivery.
Article
Chemistry, Multidisciplinary
Ya Liu, Changhong Zhao, Alan Sabirsh, Lilei Ye, Xiaoqiu Wu, Hongbin Lu, Johan Liu
Summary: The study explores the use of graphene quantum dots functionalized with polyethyleneimine as a novel mRNA delivery system that can deliver intact and functional mRNA to hepatocarcinoma cells without toxicity. While cellular toxicity remains a concern, the functionalized GQDs show promise as a potentially interesting, easy to manufacture, stable, and effective delivery system.
Article
Chemistry, Multidisciplinary
Thammanoon Thaweechai, Weekit Sirisaksoontorn, Yingyot Poo-Arporn, Narong Chanlek, Supapan Seraphin, Surachai Thachepan, Rungtiva P. Poo-Arporn, Songwut Suramitr
Summary: The transparent nanocomposite sol of graphene quantum dot and amorphous TiO2 (GQD/a-TiO2) showed enhanced photocatalytic activity in degradation of RhB due to the interactions between surface functional groups on GQD sheets and a-TiO2, leading to band gap narrowing and synergistic effects. The smaller size of GQD facilitated greater extent of interactions at nanoscopic level, resulting in improved photocatalytic performance.
JOURNAL OF NANOPARTICLE RESEARCH
(2021)
Article
Chemistry, Analytical
Nazli Simsek, Gozde Aydogdu Tig
Summary: A nanocomposite consisting of AuNPs, GQD, and poly(L-lysine) was prepared for highly sensitive electrochemical determination of dopamine and serotonin neurotransmitters. The LOD values for dopamine and serotonin were calculated as 0.03 μM and 0.017 μM, respectively. The nanocomposite showed high recovery values when used for determining dopamine and serotonin contents in fetal bovine serum samples and pharmaceutical formulations.
Article
Chemistry, Multidisciplinary
Kaixiang Chen, Chufan Zhang, Xiaoxian Zang, Fuyuan Ma, Yuanzhen Chen, Yaping Dan
Summary: Coating graphene with quantum dots enhances light absorption and leads to high photogain. Light illumination narrows down the surface depletion region, creating a photovoltage that gates the graphene, resulting in high photogain in graphene.
Article
Polymer Science
Solmaz Massoudi, Massoumeh Bagheri, Younes Beygi Khosrowshahi, Maryam Hosseini
Summary: Two series of pH-sensitive poly (N-vinyl imidazole)/nitrogen-doped graphene quantum dots nanocomposite hydrogels (PVI/NGQD) were successfully synthesized via in situ polymerization method. The swelling behavior of the hydrogels was influenced by the crosslinker and NGQD content, and the incorporation of NGQDs increased the crystallinity and thermal stability of the nanocomposites. The nanocomposite hydrogels exhibited antibacterial activity and potential for biomedical applications.
Article
Materials Science, Multidisciplinary
Hamed Hashemi, Hassan Namazi
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2018)
Article
Electrochemistry
Amin Goljanian Tabrizi, Nasser Arsalani, Abdolkhaled Mohammadi, Laleh Saleh Ghadimi, Iraj Ahadzadeh, Hassan Namazi
ELECTROCHIMICA ACTA
(2018)
Article
Biochemistry & Molecular Biology
Monireh Rasoulzadehzali, Hassan Namazi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Environmental Sciences
N. Alipour, H. Namazi
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Siamak Javanbakht, Malihe Pooresmaeil, Hamed Hashemi, Hassan Namazi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Polymer Science
Yashar Ahmadian, Asghar Bakravi, Hamed Hashemi, Hassan Namazi
Article
Chemistry, Applied
Siamak Javanbakht, Malihe Pooresmaeil, Hassan Namazi
CARBOHYDRATE POLYMERS
(2019)
Article
Biochemistry & Molecular Biology
Siamak Javanbakht, Ahmad Shaabani
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Materials Science, Biomaterials
Siamak Javanbakht, Parinaz Nezhad-Mokhtari, Ahmad Shaabani, Nasser Arsalani, Marian Ghorbani
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Chemistry, Physical
Malihe Pooresmaeil, Siamak Javanbakht, Saman Behzadi Nia, Hassan Namazi
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2020)
Article
Chemistry, Applied
Fereshteh Bahri, Mehrdad Shadi, Reza Mohammadian, Siamak Javanbakht, Ahmad Shaabani
Summary: Functionalization of cellulose via multicomponent reactions (MCRs) resulted in the synthesis of an efficient novel biocatalyst for the C-H functionalization reaction of N-acylhydrazones to synthesize 1,3,4-oxadiazoles, showcasing high yields, non-toxicity, mild reaction conditions, operational simplicity, and reusability.
CARBOHYDRATE POLYMERS
(2021)
Article
Nanoscience & Nanotechnology
Siamak Javanbakht, Ayda Saboury, Ahmad Shaabani, Reza Mohammadi, Marjan Ghorbani
ACS APPLIED BIO MATERIALS
(2020)
Review
Nanoscience & Nanotechnology
Siamak Javanbakht, Ahmad Shaabani
ACS APPLIED BIO MATERIALS
(2020)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)