Antiproliferative effect of urolithin A, the ellagic acid-derived colonic metabolite, on hepatocellular carcinoma HepG2.2.15 cells by targeting Lin28a/let-7a axis

Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21

(2016) Benhong Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Urolithin A, C, and D, but not iso-urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes

(2016) Inhae Kang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A novel mechanism of hepatocellular carcinoma cell apoptosis induced by lupeol via Brain-Derived Neurotrophic Factor Inhibition and Glycogen Synthase Kinase 3 beta reactivation

(2015) Lingli Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer

(2015) Tianzhen Wang et al.   Molecular Cancer

In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells

(2015) Yun Wang et al.   TOXICOLOGY IN VITRO

Hydrodynamic Transfection for Generation of Novel Mouse Models for Liver Cancer Research

(2014) Xin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far

(2013) Juan Carlos Espín et al.   Evidence-based Complementary and Alternative Medicine

Hepatitis B virus X protein upregulates Lin28A/Lin28B through Sp-1/c-Myc to enhance the proliferation of hepatoma cells

(2013) X You et al.   ONCOGENE

Epigenetics of hepatocellular carcinoma: Role of microRNA

(2013) Sharad Khare   WORLD JOURNAL OF GASTROENTEROLOGY

EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene

(2011) N Khodayari et al.   CANCER GENE THERAPY

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

Hepatitis B virus X gene and hepatocarcinogenesis

(2011) Sue-Ann Ng et al.   JOURNAL OF GASTROENTEROLOGY

Urolithins, Intestinal Microbial Metabolites of Pomegranate Ellagitannins, Exhibit Potent Antioxidant Activity in a Cell-Based Assay

(2009) Dobroslawa Bialonska et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling†

(2009) Meenakshi Sharma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3

(2008) Wing Pui Tsang et al.   APOPTOSIS

Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

(2008) Qing Ji et al.   BMC CANCER

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression

(2008) Hong Tang et al.   HEPATOLOGY

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

Hepatitis B virus and hepatocellular carcinoma

(2004) Patrick Arbuthnot et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY