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Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma

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Notch1-MAPK Signaling Axis Regulates CD133 + Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis

(2016) Dhiraj Kumar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Targeted therapies for ER+/HER2- metastatic breast cancer

(2015) Mutsuko Yamamoto-Ibusuki et al.   BMC Medicine

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Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism

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Cytokines induce effector T-helper cells during invasive aspergillosis; what we have learned about T-helper cells?

(2015) Raman Thakur et al.   Frontiers in Microbiology

Osteopontin as a therapeutic target for cancer

(2014) Monalisa Bandopadhyay et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cross-talk between Endoplasmic Reticulum (ER) Stress and the MEK/ERK Pathway Potentiates Apoptosis in Human Triple Negative Breast Carcinoma Cells

(2014) Swatilekha Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expedient preparative isolation and tandem mass spectrometric characterization of C-seco triterpenoids from Neem oil

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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

(2014) Sung-Kyun Ko et al.   Nature Chemistry

Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis

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Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS-ERK Signaling

(2014) M. Will et al.   Cancer Discovery

Expedient preparative isolation, quantification and characterization of limonoids from Neem fruits

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Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: A systemic review and meta-analysis

(2013) Zhifei Cao et al.   EUROPEAN JOURNAL OF CANCER

CDCP1 Regulates the Function of MT1-MMP and Invadopodia-Mediated Invasion of Cancer Cells

(2013) Yuri Miyazawa et al.   MOLECULAR CANCER RESEARCH

Hypoxia-driven osteopontin contributes to breast tumor growth through modulation of HIF1α-mediated VEGF-dependent angiogenesis

(2013) R Raja et al.   ONCOGENE

Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin

(2013) S Kale et al.   ONCOGENE

Functional Characterization of Stromal Osteopontin in Melanoma Progression and Metastasis

(2013) Santosh Kumar et al.   PLoS One

Neem oil limonoids induces p53-independent apoptosis and autophagy

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Andrographolide Inhibits Osteopontin Expression and Breast Tumor Growth Through Down Regulation of PI3 Kinase/Akt Signaling Pathway

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(2011) Qin-Gang Tan et al.   CHEMICAL REVIEWS

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(2011) Mansoor Ahmed et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

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(2011) Takashi Kikuchi et al.   JOURNAL OF NATURAL PRODUCTS

Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-κB in colon cancer cells

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p38 Kinase Is Crucial for Osteopontin-Induced Furin Expression That Supports Cervical Cancer Progression

(2010) V. Kumar et al.   CANCER RESEARCH

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells

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Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells

(2010) Priyanka Sharma et al.   Molecular Cancer

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-κB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

(2010) Mansoor Ahmed et al.   Molecular Cancer

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

(2009) R. Behera et al.   CARCINOGENESIS

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Osteopontin Promotes Vascular Endothelial Growth Factor Dependent Breast Tumor Growth and Angiogenesis via Autocrine and Paracrine Mechanisms

(2008) G. Chakraborty et al.   CANCER RESEARCH

Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells

(2008) Dong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gedunin, a Novel Hsp90 Inhibitor: Semisynthesis of Derivatives and Preliminary Structure−Activity Relationships

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