Melatonin protects against Aβ-induced neurotoxicity in primary neurons via miR-132/PTEN/AKT/FOXO3a pathway

microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheimer’s disease

(2017) Evgenia Salta et al.   FASEB JOURNAL

The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster

(2017) Sabrina Pichler et al.   NEUROBIOLOGY OF AGING

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease

(2017) Gargi Ganguly et al.   Drug Design Development and Therapy

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer’s disease

(2016) Qiong-Bin Zhu et al.   BRAIN

miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain

(2016) Evgenia Salta et al.   EMBO Molecular Medicine

Melatonin attenuates neuronal apoptosis through up-regulation of K+-Cl−cotransporter KCC2 expression following traumatic brain injury in rats

(2016) Haijian Wu et al.   JOURNAL OF PINEAL RESEARCH

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

(2016) Shira Knafo et al.   NATURE NEUROSCIENCE

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

(2015) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

The neuroprotective and anti-apoptotic effects of melatonin on hemolytic hyperbilirubinemia-induced oxidative brain damage

(2015) Asilay Pazar et al.   JOURNAL OF PINEAL RESEARCH

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

CREB expression mediates amyloid β-induced basal BDNF downregulation

(2015) Elyse Rosa et al.   NEUROBIOLOGY OF AGING

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

(2013) Hon-Kit Andus Wong et al.   HUMAN MOLECULAR GENETICS

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

(2012) Helen L. Scott et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Regulation of Forkhead Transcription Factor FoxO3a Contributes to Calorie Restriction-induced Prevention of Alzheimer's Disease-type Amyloid Neuropathology and Spatial Memory Deterioration

(2010) Weiping Qin et al.   Annals of the New York Academy of Sciences

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

(2010) Judit Remenyi et al.   BIOCHEMICAL JOURNAL

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes

(2010) Pil-Jae Kong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

An evaluation of the neuroprotective effects of melatonin in an in vitro experimental model of age-induced neuronal apoptosis

(2009) Marta Tajes Orduña et al.   JOURNAL OF PINEAL RESEARCH

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease

(2009) James M. Olcese et al.   JOURNAL OF PINEAL RESEARCH

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression

(2009) H. Kawashima et al.   NEUROSCIENCE

Regulation of non-coding RNA networks in the nervous system—What's the REST of the story?

(2009) Irfan A. Qureshi et al.   NEUROSCIENCE LETTERS

Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism

(2008) Masilamoni J. Gunasingh et al.   LIFE SCIENCES