Article
Materials Science, Multidisciplinary
Maryam Zamani, Nahid Tavakkoli, Nasrin Soltani
Summary: A simple and low-cost electrochemical sensor based on graphene quantum dots (GQDs) was developed for the measurement of the anti-cancer drug MTX. The sensor was modified with gold nanoparticles and thiol organic compounds on GQDs, showing improved detection performance. The results demonstrate that the prepared sensor has better application potential for MTX measurement compared to previous studies.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Environmental Sciences
Xiaolin Zhu, Liju Tan, Ting Zhao, Wenqiu Huang, Xin Guo, Jiayin Wang, Jiangtao Wang
Summary: The toxic effects of nano-ZnO and GQDs on dinoflagellate Gymnodinium were investigated. Nano-ZnO had slight effects on algal cell growth, while the growth inhibition of Gymnodinium increased with increasing GQDs concentration. Both nanoparticles induced accumulation of reactive oxygen species and activated intracellular antioxidant defense system. The combined exposure of nano-ZnO and GQDs showed decreased inhibitory effects compared to GQDs alone.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Physical
Oluwasesan Adegoke, Niamh Nic Daeid
Summary: A novel fluorescence aptasensor was developed for ultrasensitive detection of arsenic (As) contamination, with the probe successfully applied in environmental and biological samples. By optimizing the probe composition, selective and quantitative analysis of As(III) was achieved with high sensitivity.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Chemistry, Analytical
Li Ruiyi, Jia Hui, Li Nana, Xu Dan, Li Zaijun
Summary: The paper describes the synthesis of gold-graphene hybrid using histidine-functionalized graphene quantum dot as the linker between gold and graphene. The hybrid exhibits good dispersion and catalytic activity. By coupling with DNA cycling signal amplification, the hybrid is able to detect chlorpyrifos in fruits with high sensitivity and selectivity.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Yu Jin, Ke Liu, Guangqiang Li, Chengfei Li, Zhidong Xiao, Chao Yuan, Jinquan Li
Summary: This study successfully achieved high-sensitivity fluorescence detection of thiram triggered by TCEP, demonstrating the potential in developing point-of-care sensors. Additionally, a paper sensor that can be visually observed by naked eye was developed, providing new possibilities for pesticide detection. By using an in situ reduction strategy, the interaction between the target and nanoprobe was improved, leading to high sensitivity detection.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Xiaokun Wen, Jia Hua, Yadan Ding, Zhipeng Li, Guorui Wang, Hancheng Zhu, Jun Li, Xia Hong
Summary: A dual-mode method based on PL-RLS was developed for sensitive and accurate detection of miRNA-141. This method has a low detection limit and a linear detection range, allowing for mutual validation to ensure the accuracy and reliability of the detection results.
ANALYTICA CHIMICA ACTA
(2023)
Article
Spectroscopy
Zhenping Liu, Jun Zhou, Xianfeng Wang, Jinsong Zhao, Peng Zhao, Yi Ma, Suyi Zhang, Danqun Huo, Changjun Hou, Kang Ren
Summary: In this work, a novel aptasensor based on the fluorescence quenching property of graphene oxide (GO) and the fluorescence characteristic of cadmium selenide quantum dots (CdSe QDs) was developed for highly sensitive detection of fluoroquinolones contamination. The aptasensor showed reliable detection performance and promising potential for the detection of fluoroquinolones.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Energy & Fuels
Ekta Roy, Achala Nagar, Ashwini Sharma, Souvik Roy, Souvik Pal
Summary: Graphene quantum dots (GQDs) are a new type of carbonaceous material with exceptional physicochemical properties and high surface area, derived from two-dimensional graphene. GQDs exhibit new properties due to quantum confinement and edge effect, similar to graphene, and are used in sensing, bioimaging, catalysis, supercapacitors, adsorption, and separation applications.
JOURNAL OF ENERGY STORAGE
(2021)
Article
Chemistry, Applied
Zahra Khoshbin, Marzieh Moeenfard, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: A simple aptasensor embedded in a micropipette tip is developed for label-free monitoring of acrylamide. The aptasensor utilizes the formation of a triple-helix molecular switch structure to induce the aggregation of gold nanoparticles. A smartphone imaging readout strategy enables the quantification of acrylamide based on the color change of the solution inside the micropipette tip. This aptasensor shows good selectivity and can successfully quantify acrylamide in various food samples.
Article
Chemistry, Applied
Reena K. Sajwan, Pratima R. Solanki
Summary: A rapid and sensitive hybrid nanosensor using graphene quantum dots and gold nanoparticles was developed for detecting gentamicin in milk and egg samples. The nanosensor showed excellent recovery efficiency and can be used as a promising tool for speedy monitoring of food quantity.
Review
Energy & Fuels
Norazuwana Shaari, Siti Kartom Kamarudin, Raihana Bahru
Summary: Carbon quantum dots (CQDs) and graphene quantum dots (GQDs) are frequently mentioned in recent studies for their unique potential in electrical, optical, and optoelectrical properties. They are highly stable due to their carbon material and environmentally friendly nature. Various production methods and additive materials can enhance their performance, with shapes and sizes influenced by different parameters. Applications in fuel cell technology have shown improved performance.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2021)
Article
Physics, Applied
Kai Yang, Shenghui Kang, Xiaoyu Wu, Bohua Liu, Chongling Sun, Yanyan Wang
Summary: A high NIR sensitivity and spectral selectivity photothermal detector was developed by modifying a photothermal layer of reduced graphene oxide-Au nanorods hybrid. The detector converts light energy into heat and measures resistance changes. The hybrid material exhibits remarkable photothermal conversion efficiency and dependence on spectral response, resulting in high sensitivity to illumination in the wavelength range from 700 to 1000 nm.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Cansu Esen, Baris Kumru
Summary: This paper presents a liquid-liquid printing technique based on graphitic carbon nitride, which can form thiol-ene polymer beads through photopolymerization in a simple and scalable manner.
NANOSCALE ADVANCES
(2022)
Article
Biochemistry & Molecular Biology
Saloni Kakkar, Sakshi Chauhan, Manojkumar Rohit, Vijayender Bhalla
Summary: This study reports a label-free ultrasensitive electrochemical aptasensor (GO@GNP-A) for detecting cardiac biomarker Troponin I (TnI). The nanohybrid of graphene oxide (GO) and gold nanoparticles (GNP-A) is self-assembled to form the nanohybrid (GO@GNP-A), onto which the biomarker protein is analyzed. TnI interactions at the aptamer biointerfaced nanohybrid surface cause electrochemical signal enhancement. The sensitivity of this nanohybrid aptasensor platform is 0.001 pg/mL. The study has been further validated in clinical samples for early, sensitive, and efficient point-of-care detection of TnI in cases of Acute Myocardial Infarction (AMI).
BIOELECTROCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Wei Fu, Jiefu Yin, Huaqiang Cao, Zhongfu Zhou, Junying Zhang, Jingjing Fu, Jamie H. Warner, Cheng Wang, Xiaofang Jia, G. Neville Greaves, Anthony K. Cheetham
Summary: The photoluminescence blinking behavior of single quantum dots under steady illumination is a significant yet controversial topic. It hinders the use of single quantum dots in bioimaging. Different mechanisms, particularly the non-radiative Auger recombination mechanism, have been proposed to explain it. Fluorescence non-blinking is observed in photocharged single graphene quantum dots (GQDs) due to the presence of singly charged trions that maintain photon emission through radiative and non-radiative Auger recombination. This phenomenon is attributed to the different energy levels caused by oxygen-containing functional groups in the GQDs, and the suppression of blinking is attributed to trap site filling caused by Coulomb blockade.
ADVANCED MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Priyanga Kumar, Noel Nesakumar, Jayashree Gopal, Sakthivel Sivasubramanian, Srinivasan Vedantham, John Bosco Balaguru Rayappan
Summary: This study developed an electrochemical biosensor for measuring MG levels in the plasma of type-2 diabetes mellitus patients. The biosensor showed a wide linear concentration range, high sensitivity, and a 90% correlation with ELISA data. It also exhibited a significant correlation with HbA1c and fasting plasma glucose levels.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rimsha B. Jamal, Ulrich Bay Gosewinkel, Elena E. Ferapontova
Summary: Pathogen-triggered infections are a severe global threat to human health. Researchers have developed a fast and inexpensive electrocatalytic aptamer assay for the specific and ultrasensitive detection of E. coli, allowing for timely treatment and prevention. The method is fast, sensitive, and can be used in field and point-of-care applications for analysis of bacteria in the human environment.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Miao Liu, Yuwei Wang, Shanshan Tang, Wei Wang, Axin Liang, Aiqin Luo
Summary: An unlabeled ratiometric molecular imprinted electrochemiluminescence sensor was developed for the determination of trace uric acid using MXene@NaAsc, CdSe@ZnS quantum dots, and molecularly imprinted polymer composites modified glass carbon electrode. This sensor, with easy preparation, great selectivity, and excellent sensitivity, successfully detected uric acid in human serum.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Charlotte Da Silva, Camille Lamarche, Carole Pichereaux, Emmanuelle Mouton-Barbosa, Gauthier Demol, Sebastien Boisne, Etienne Dague, Odile Burlet-Schiltz, Flavien Pillet, Marie-Pierre Rols
Summary: Low-energy electron beams (LEEB) are a safe and practical sterilization solution for industrial applications. To address the limitations of LEEB, we developed a low-energy pulsed electron beam generator (LEPEB) that can effectively and efficiently eradicate bacteria in a wide range of industrial applications.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny, Miroslav Fojta
Summary: In this study, N-methyl mesoporphyrin IX (NMM) was utilized as a voltammetric probe for the electrochemical detection of G4s. The detection of NMM was achieved by cyclic voltammetry on a hanging mercury drop electrode (HMDE) with a limit of detection (LOD) of 40 nM. The reduction signal of NMM was found to be significantly higher when G4 oligodeoxynucleotides (G4 ODNs) were present compared to single- or double-stranded ODNs or unfolded ODNs capable of forming G4s. Gradual transition from unstructured single strand to G4, induced by increasing concentrations of the G4 stabilizing K+ ions, was detected for the first time using electrochemical methods. Circular dichroism spectroscopy provided support for the obtained results. This work expands on the utilization of electrochemical probes for DNA secondary structure recognition and offers a proof of principle for the development of novel electroanalytical methods for nucleic acid structure studies.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Mengjiao Zhu, Yu Liu, Meiyue Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: Early rapid diagnosis of COVID-19 is crucial for reducing the risk of severe symptoms and loss of lung function. Researchers have proposed an ultrafast and ultrasensitive DNA sensor that can accurately detect the virus in a short period of time, with outstanding selectivity.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Fatima-Zahra Ait-Itto, James A. Behan, Mathieu Martinez, Frederic Barriere
Summary: This study investigated the feasibility of using ancient marine sediments as inoculum for bioanode development in microbial fuel cells (MFC). The results showed the presence of two exoelectrogenic bacterial genera in these iron-rich sediments and confirmed that the development of the bioanode derived from the native microbiota. This study has important implications for understanding the role of these bacteria in broader paleoenvironmental phenomena.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Issa Fall, Bastien Doumeche, Sofiene Abdellaoui, Caroline Remond, Harivony Rakotoarivonina, Marjorie Ochs
Summary: This article presents a novel electrochemical tool based on lignin-coated paper electrodes for the detection and characterization of ligninolytic activity. The suitability of this method has been demonstrated using a catalaseperoxidase isolated from Thermobacillus xylanilyticus.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Chenyi Zhuo, Dehong Yu, Jiuying Cui, Zichun Song, Qianli Tang, Xianjiu Liao, Zhao Liu, Ning Xin, Lu Lou, Fenglei Gao
Summary: A label-free detection strategy for quantification of Apolipoprotein A4 (Apo-A4) has been developed based on rolling circle amplification (RCA) and proximity hybridization-induced DNAzyme-driven bipedal DNA walker. This method shows high sensitivity and selectivity for a wide range of protein targets.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xiaopeng Hou, Qiongyi Cheng, Hui Wang
Summary: A self-cleaning paper-based microfluidic biosensor was developed using hydrophobic paper decorated with polymeric octadecyl trichlorosilane. The biosensor showed improved performance and could effectively measure the concentration of copper ions in livestock feed and manure.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Yanling Zhang, Jie Wang, Min Liu, Yun Ni, Yao Yue, Dawei He, Ruijiang Liu
Summary: An innovative electrochemical biosensor has been developed for sensitive detection of HER2 protein, an important tumor marker for breast cancer diagnosis and treatment evaluation. The biosensor utilizes specific recognition probes and nanomaterials, along with a unique sensing strategy, to achieve ultra-low detection limit and demonstrate excellent selectivity, reproducibility, and stability.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Humayun Amir, Vasanth Subramanian, Sundaram Sornambikai, Nagamony Ponpandian, Chinnusamy Viswanathan
Summary: In this study, the electrochemical detection of breast cancer biomarker HER2 was successfully achieved using the N-CQDs/GS as the detector. The BSA-modified HER2 Antibody/N-CQDs/GS immunoelectrode preserved excellent activity for the biosensor, while the GS electrode provided high stability and conductivity. The method exhibited a low detection limit and optimal specificity, stability, and reproducibility for detecting HER-2 protein in untreated blood samples from breast cancer patients.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ilona Uzieliene, Anton Popov, Raminta Vaiciuleviciute, Gailute Kirdaite, Eiva Bernotiene, Almira Ramanaviciene
Summary: This review discusses the application of polypyrrole (Ppy), an electroconductive polymer, in cell culture experiments with electrical stimulation (ES) and its potential for tissue regeneration. Ppy can direct ES to cells and stimulate differentiation towards different cell lineages. Different types of Ppy materials and their combination with active molecules are explored.
BIOELECTROCHEMISTRY
(2024)