Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically?

Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1

(2018) A. Mallat et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

(2018) Thomas G. McWilliams et al.   Cell Metabolism

Basal mitophagy is widespread inDrosophilabut minimally affected by loss of Pink1 or parkin

(2018) Juliette J. Lee et al.   JOURNAL OF CELL BIOLOGY

LRRK2 mediated Rab8a phosphorylation promotes lipid storage

(2018) Miao Yu et al.   Lipids in Health and Disease

Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration

(2018) Ga Ram Jeong et al.   Molecular Neurodegeneration

Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease

(2018) Gonzalo S. Nido et al.   NEUROBIOLOGY OF AGING

Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons

(2018) Jason Schapansky et al.   NEUROBIOLOGY OF DISEASE

Multiple pathways for mitophagy: A neurodegenerative conundrum for Parkinson’s disease

(2018) Charleen T. Chu   NEUROSCIENCE LETTERS

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease

(2018) Ken Y. Hui et al.   Science Translational Medicine

Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I

(2018) Lucas Robke et al.   Chemical Science

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Streptozotocin-Induced Sporadic Alzheimer's Disease: Selection of Appropriate Dose

(2018) Jogender Mehla et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate

(2017) Shilpy Dixit et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model

(2017) Wenzhang Wang et al.   HUMAN MOLECULAR GENETICS

Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer’s Disease

(2017) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial genes are altered in blood early in Alzheimer's disease

(2017) Katie Lunnon et al.   NEUROBIOLOGY OF AGING

Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease

(2017) Adam L. Orr et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial involvement in memory impairment induced by scopolamine in rats

(2017) Maylin Wong-Guerra et al.   NEUROLOGICAL RESEARCH

Temporal-Spatial Profiling of Pedunculopontine Galanin-Cholinergic Neurons in the Lactacystin Rat Model of Parkinson’s Disease

(2017) Joanna L. Elson et al.   NEUROTOXICITY RESEARCH

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease

(2017) Patricia Martín-Maestro et al.   Oxidative Medicine and Cellular Longevity

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients

(2017) J. R. Bedarf et al.   Genome Medicine

Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation

(2017) Patricia Martín-Maestro et al.   Frontiers in Molecular Neuroscience

Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease

(2017) María J. Pérez et al.   Frontiers in Neuroscience

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology

(2017) Sabrina Contino et al.   Frontiers in Physiology

Mitochondria and α-Synuclein: Friends or Foes in the Pathogenesis of Parkinson’s Disease?

(2017) Gaia Faustini et al.   Genes

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial superclusters influence age of onset of Parkinson’s disease in a gender specific manner in the Cypriot population: A case-control study

(2017) Andrea Georgiou et al.   PLoS One

Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease

(2017) Simone Bido et al.   Scientific Reports

An antioxidant specifically targeting mitochondria delays progression of Alzheimer’s disease-like pathology

(2016) Natalia Stefanova et al.   Aging-US

Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

(2016) Diana Matheoud et al.   CELL

Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease

(2016) Chung-Han Hsieh et al.   Cell Stem Cell

Mitochondrial Respiration in the Platelets of Patients with Alzheimer’s Disease

(2016) Zden|k FiŠar et al.   Current Alzheimer Research

LRRK2 Kinase Inhibition as a Therapeutic Strategy for Parkinson's Disease, Where Do We Stand?

(2016) Jean-Marc Taymans et al.   Current Neuropharmacology

Mitochondrial DNA variants as genetic risk factors for Parkinson disease

(2016) C. W. Liou et al.   EUROPEAN JOURNAL OF NEUROLOGY

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

(2016) Thomas G. McWilliams et al.   JOURNAL OF CELL BIOLOGY

Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

(2016) Anamitra Ghosh et al.   Journal of Neuroimmune Pharmacology

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants

(2016) Joanna Wojsiat et al.   MOLECULAR NEUROBIOLOGY

Somatic mtDNA variation is an important component of Parkinson's disease

(2016) Jonathan Coxhead et al.   NEUROBIOLOGY OF AGING

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish

(2016) Nukala Sarath Babu et al.   PROTEOMICS

Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration

(2016) Kelly L. Stauch et al.   Proteomics Clinical Applications

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease

(2016) Christian Dölle et al.   Nature Communications

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

(2016) Martin Steger et al.   eLife

Altered Mitochondrial Respiration and Other Features of Mitochondrial Function inParkin-Mutant Fibroblasts from Parkinson’s Disease Patients

(2016) William Haylett et al.   Parkinsons Disease

Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects

(2016) Y Kim et al.   Translational Psychiatry

Mitochondrial dysfunction in aging: Much progress but many unresolved questions

(2015) Brendan A.I. Payne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial DNA Haplogroups and the Risk of Sporadic Parkinson′s Disease in Han Chinese

(2015) Ning Wang et al.   CHINESE MEDICAL JOURNAL

Mitochondrial Deficits Accompany Cognitive Decline Following Single Bilateral Intracerebroventricular Streptozotocin

(2015) Ramesh Paidi et al.   Current Alzheimer Research

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

(2015) Consiglia Pacelli et al.   CURRENT BIOLOGY

LRRK2 mutations and neurotoxicant susceptibility

(2015) Jang-Won Lee et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cellular processes associated with LRRK2 function and dysfunction

(2015) Rebecca Wallings et al.   FEBS Journal

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

(2015) Dominik Haddad et al.   FEBS LETTERS

Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression

(2015) Anastasia G. Henry et al.   HUMAN MOLECULAR GENETICS

Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation

(2015) Annica Rönnbäck et al.   JOURNAL OF NEUROCHEMISTRY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Alterations in mitochondrial number and function in Alzheimer’s disease fibroblasts

(2015) Nora E. Gray et al.   METABOLIC BRAIN DISEASE

Fibroblast Biomarkers of Sporadic Parkinson’s Disease and LRRK2 Kinase Inhibition

(2015) G. A. Smith et al.   MOLECULAR NEUROBIOLOGY

Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson’s disease

(2015) Ilse S. Pienaar et al.   Molecular Neurodegeneration

Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury

(2015) Denis Silachev et al.   MOLECULES

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice

(2015) M. Yue et al.   NEUROBIOLOGY OF DISEASE

UDCA exerts beneficial effect on mitochondrial dysfunction inLRRK2G2019Scarriers and in vivo

(2015) Heather Mortiboys et al.   NEUROLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

(2015) Daniel A. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective Effects of Citrus reticulata in Scopolamine-Induced Dementia Oxidative Stress in Rats

(2014) Manal El-Khadragy et al.   CNS & Neurological Disorders-Drug Targets

PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402

(2014) Liesbeth Aerts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations

(2014) Noha F. Abdelkader et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease

(2014) Laurie H. Sanders et al.   NEUROBIOLOGY OF DISEASE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo

(2014) Phillip M. Rappold et al.   Nature Communications

Epoxyeicosatrienoic acids pretreatment improves amyloid β-induced mitochondrial dysfunction in cultured rat hippocampal astrocytes

(2013) Pallabi Sarkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TigarBcauses mitochondrial dysfunction and neuronal loss in PINK1 deficiency

(2013) Laura J. Flinn et al.   ANNALS OF NEUROLOGY

Does Uncoupling Protein 2 Expression Qualify as Marker of Disease Status in LRRK2-Associated Parkinson's Disease?

(2013) Anne Grünewald et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

(2013) Xueqi Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mesencephalic complex I deficiency does not correlate with parkinsonism in mitochondrial DNA maintenance disorders

(2013) Eino J. H. Palin et al.   BRAIN

Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson’s disease

(2013) Heather Mortiboys et al.   BRAIN

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson’s disease

(2013) Ilse S. Pienaar et al.   Brain Structure & Function

A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1

(2013) Nicholas T. Hertz et al.   CELL

Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease

(2013) Sonia C. Correia et al.   Current Alzheimer Research

Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation

(2013) Yu-Chin Su et al.   HUMAN MOLECULAR GENETICS

Steroid hormone synthesis in mitochondria

(2013) Walter L. Miller   MOLECULAR AND CELLULAR ENDOCRINOLOGY

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

(2013) Samuel A. Hasson et al.   NATURE

Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease

(2013) G. Hudson et al.   NEUROLOGY

A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

(2013) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Guide to Neurotoxic Animal Models of Parkinson's Disease

(2013) K. Tieu   Cold Spring Harbor Perspectives in Medicine

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Attenuation of scopolamine-induced cognitive dysfunction by obovatol

(2012) Dong-Young Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease

(2012) María E. Solesio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Mitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer’s disease

(2012) S. Wang et al.   EUROPEAN JOURNAL OF NEUROLOGY

Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype

(2012) Mahesh Ramamoorthy et al.   FREE RADICAL BIOLOGY AND MEDICINE

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

(2012) Tatiana D. Papkovskaia et al.   HUMAN MOLECULAR GENETICS

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

(2012) X. Wang et al.   HUMAN MOLECULAR GENETICS

A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity

(2012) X. Qi et al.   JOURNAL OF CELL SCIENCE

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

(2012) Dun-Xian Tan et al.   JOURNAL OF PINEAL RESEARCH

Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice

(2012) Adrian C. Lo et al.   NEUROBIOLOGY OF DISEASE

Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease

(2012) Eugenia Trushina et al.   PLoS One

Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease

(2011) Terina N. Martinez et al.   ANTIOXIDANTS & REDOX SIGNALING

Rotenone, Paraquat, and Parkinson’s Disease

(2011) Caroline M. Tanner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

(2011) M. J. Calkins et al.   HUMAN MOLECULAR GENETICS

Mutations inLRRK2increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death

(2011) Dario C. Angeles et al.   HUMAN MUTATION

Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients

(2011) Hua She et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: A behavioral, biochemical and cerebral blood flow study

(2011) Shakti Deep Pachauri et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) M. J. McManus et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial DNA deletions cause the biochemical defect observed in Alzheimer's disease

(2011) Kim J. Krishnan et al.   NEUROBIOLOGY OF AGING

Deep brain stimulation in rapidly progressive parkinson-dystonia syndrome due to mitochondrial disorder

(2011) Esther Pelzer et al.   PARKINSONISM & RELATED DISORDERS

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk

(2011) E. Zampese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

(2010) Anamitra Ghosh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2

(2010) H. Mortiboys et al.   NEUROLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

(2009) Estela Area-Gomez et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

(2009) L. Flinn et al.   BRAIN

Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons

(2009) Takuma Uo et al.   EXPERIMENTAL NEUROLOGY

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Differential effects of melatonin on amyloid-β peptide 25-35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

(2009) Weiguo Dong et al.   JOURNAL OF PINEAL RESEARCH

Levels of reduced and oxidized coenzymeQ-10 and 8-hydroxy-2′-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process

(2009) Chiaki Isobe et al.   NEUROSCIENCE LETTERS

Age, Neuropathology, and Dementia

(2009) George M. Savva et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons

(2008) Amy K. Reeve et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients

(2008) Xinglong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

Targeting lipophilic cations to mitochondria

(2008) Michael P. Murphy   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Assembly of the oxidative phosphorylation system in humans: What we have learned by studying its defects

(2008) Erika Fernández-Vizarra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Mitochondrial DNA haplogroups and subhaplogroups are associated with Parkinson’s disease risk in a Polish PD cohort

(2008) Katarzyna Gaweda-Walerych et al.   JOURNAL OF NEURAL TRANSMISSION

Mitochondrial DNA haplogroups J and K are not protective for Parkinson's disease in the Australian community

(2008) Prachi Mehta et al.   MOVEMENT DISORDERS

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Amyloid-  overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

(2008) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex I deficiency in Parkinson's disease frontal cortex

(2007) W. Davis Parker et al.   BRAIN RESEARCH

Bilateral striatal necrosis, dystonia and multiple mitochondrial DNA deletions: Case study and effect of deep brain stimulation

(2007) Maria Stella Aniello et al.   MOVEMENT DISORDERS