G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome
出版年份 2015 全文链接
标题
G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome
作者
关键词
-
出版物
FEBS LETTERS
Volume 589, Issue 14, Pages 1653-1668
出版商
Wiley
发表日期
2015-05-13
DOI
10.1016/j.febslet.2015.05.003
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Potassium Ion-Dependent RNA Structural Switch Regulates Human Pre-miRNA 92b Maturation
- (2015) Gayan Mirihana Arachchilage et al. CHEMISTRY & BIOLOGY
- The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing
- (2015) Anastassios Vourekas et al. GENES & DEVELOPMENT
- Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration
- (2015) Primož Šket et al. NEUROBIOLOGY OF AGING
- Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
- (2015) Michael C. Chen et al. NUCLEIC ACIDS RESEARCH
- Small-molecule quadruplex-targeted drug discovery
- (2014) Stephan A. Ohnmacht et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia
- (2014) Sarah Mizielinska et al. CURRENT OPINION IN NEUROLOGY
- FANCJ promotes DNA synthesis through G-quadruplex structures
- (2014) P. Castillo Bosch et al. EMBO JOURNAL
- Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS
- (2014) Janis Bennion Callister et al. EXPERIMENTAL NEUROLOGY
- A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression
- (2014) K. Skourti-Stathaki et al. GENES & DEVELOPMENT
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- PIWI proteins and PIWI-interacting RNAs in the soma
- (2014) Robert J. Ross et al. NATURE
- G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD
- (2014) Lucas T Gray et al. Nature Chemical Biology
- Unconventional features of C9ORF72 expanded repeat in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
- (2014) Sabina Vatovec et al. NEUROBIOLOGY OF AGING
- Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
- (2014) Zhaoming Su et al. NEURON
- Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
- (2014) Xinmei Wen et al. NEURON
- Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability
- (2014) Kaalak Reddy et al. NUCLEIC ACIDS RESEARCH
- G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments
- (2014) Pavel Ivanov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- G quadruplex RNA structures in PSD-95 mRNA: potential regulators of miR-125a seed binding site accessibility
- (2014) Snezana Stefanovic et al. RNA
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- R-loops Associated with Triplet Repeat Expansions Promote Gene Silencing in Friedreich Ataxia and Fragile X Syndrome
- (2014) Matthias Groh et al. PLoS Genetics
- Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region
- (2014) Erick W. Loomis et al. PLoS Genetics
- Telomeric noncoding RNA: telomeric repeat-containing RNA in telomere biology
- (2014) Emilio Cusanelli et al. Wiley Interdisciplinary Reviews-RNA
- Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA
- (2014) Ruobo Zhou et al. eLife
- Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
- (2013) Ian R. Mackenzie et al. ACTA NEUROPATHOLOGICA
- C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci
- (2013) Sarah Mizielinska et al. ACTA NEUROPATHOLOGICA
- Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
- (2013) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- Large C9orf72 Hexanucleotide Repeat Expansions Are Seen in Multiple Neurodegenerative Syndromes and Are More Frequent Than Expected in the UK Population
- (2013) Jon Beck et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The miR-92b functions as a potential oncogene by targeting on Smad3 in glioblastomas
- (2013) Zhe Bao Wu et al. BRAIN RESEARCH
- The Disease-associated r(GGGGCC)nRepeat from theC9orf72Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures
- (2013) Kaalak Reddy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TMPyP4 Porphyrin Distorts RNA G-quadruplex Structures of the Disease-associated r(GGGGCC)nRepeat of theC9orf72Gene and Blocks Interaction of RNA-binding Proteins
- (2013) Bita Zamiri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study
- (2013) Marka van Blitterswijk et al. LANCET NEUROLOGY
- Pif1 family helicases suppress genome instability at G-quadruplex motifs
- (2013) Katrin Paeschke et al. NATURE
- Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
- (2013) Giulia Biffi et al. Nature Chemistry
- Quantitative visualization of DNA G-quadruplex structures in human cells
- (2013) Giulia Biffi et al. Nature Chemistry
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- CGG Repeat-Associated Translation Mediates Neurodegeneration in Fragile X Tremor Ataxia Syndrome
- (2013) Peter K. Todd et al. NEURON
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- Targeting the unfolded protein response in neurodegeneration: A new approach to therapy
- (2013) Mark Halliday et al. NEUROPHARMACOLOGY
- Detection of G-quadruplex DNA in mammalian cells
- (2013) A. Henderson et al. NUCLEIC ACIDS RESEARCH
- Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals
- (2013) Shan Xiao et al. NUCLEIC ACIDS RESEARCH
- Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control
- (2013) Ke-wei Zheng et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain
- (2013) T. J. Nowakowski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
- (2013) C. Lagier-Tourenne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
- (2013) P. N. Perrat et al. SCIENCE
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- The G4 Genome
- (2013) Nancy Maizels et al. PLoS Genetics
- Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
- (2013) David MA Mann et al. Acta Neuropathologica Communications
- A Role for Neuronal piRNAs in the Epigenetic Control of Memory-Related Synaptic Plasticity
- (2012) Priyamvada Rajasethupathy et al. CELL
- piRNAs and their involvement in male germline development in mice
- (2012) Ramesh S. Pillai et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- Tandem repeat sequence variation as causative Cis-eQTLs for protein-coding gene expression variation: The case of CSTB
- (2012) Christelle Borel et al. HUMAN MUTATION
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
- (2012) Elisa Majounie et al. LANCET NEUROLOGY
- Targeting nuclear RNA for in vivo correction of myotonic dystrophy
- (2012) Thurman M. Wheeler et al. NATURE
- Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis
- (2012) Anastassios Vourekas et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype
- (2012) Nicola J. Rutherford et al. NEUROBIOLOGY OF AGING
- Clinical features of SCA36: A novel spinocerebellar ataxia with motor neuron involvement (Asidan)
- (2012) Y. Ikeda et al. NEUROLOGY
- A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop
- (2012) P. H. Wanrooij et al. NUCLEIC ACIDS RESEARCH
- 5'-UTR RNA G-quadruplexes: translation regulation and targeting
- (2012) A. Bugaut et al. NUCLEIC ACIDS RESEARCH
- RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1
- (2012) J. E. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potential G-quadruplexes in the human long non-coding transcriptome
- (2012) Gopal Gunanathan Jayaraj et al. RNA Biology
- C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
- (2012) Pietro Fratta et al. Scientific Reports
- G-quadruplexes in RNA biology
- (2012) Stefania Millevoi et al. Wiley Interdisciplinary Reviews-RNA
- Expansion of Intronic GGCCTG Hexanucleotide Repeat in NOP56 Causes SCA36, a Type of Spinocerebellar Ataxia Accompanied by Motor Neuron Involvement
- (2011) Hatasu Kobayashi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
- (2011) Michael A. van Es et al. ANNALS OF NEUROLOGY
- Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective
- (2011) Michael R. Santoro et al. Annual Review of Pathology-Mechanisms of Disease
- DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase
- (2011) Katrin Paeschke et al. CELL
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
- (2011) Jennifer C. Darnell et al. CELL
- Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes
- (2011) Prasun Chakraborty et al. DNA REPAIR
- G–quadruplex RNA structure as a signal for neurite mRNA targeting
- (2011) Murugan Subramanian et al. EMBO REPORTS
- 3′ End Formation of PIWI-Interacting RNAs In Vitro
- (2011) Shinpei Kawaoka et al. MOLECULAR CELL
- Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation
- (2011) Pavel Ivanov et al. MOLECULAR CELL
- Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling
- (2011) Ravi S. Muddashetty et al. MOLECULAR CELL
- Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin
- (2011) Jeffrey B Carroll et al. MOLECULAR THERAPY
- PIWI-interacting small RNAs: the vanguard of genome defence
- (2011) Mikiko C. Siomi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Identification of piRNAs in the central nervous system
- (2011) E. J. Lee et al. RNA
- Allele-Selective Inhibition of MutantHuntingtinExpression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat
- (2010) Keith T. Gagnon et al. BIOCHEMISTRY
- Making sense of G-quadruplex and i-motif functions in oncogene promoters
- (2010) Tracy A. Brooks et al. FEBS Journal
- Structure, location and interactions of G-quadruplexes
- (2010) Julian L. Huppert FEBS Journal
- Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA
- (2010) E. Blackwell et al. HUMAN MOLECULAR GENETICS
- Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly
- (2010) Mohamed M. Emara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
- (2010) Dieter Edbauer et al. NEURON
- A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
- (2010) Gavin W. Collie et al. NUCLEIC ACIDS RESEARCH
- Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway
- (2010) K. Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Incidence of Fragile X Syndrome by Newborn Screening for Methylated FMR1 DNA
- (2009) Bradford Coffee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Selectivity in Ligand Recognition of G-Quadruplex Loops†
- (2009) Nancy H. Campbell et al. BIOCHEMISTRY
- Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis
- (2009) D. Drygin et al. CANCER RESEARCH
- The structures of quadruplex nucleic acids and their drug complexes
- (2009) Stephen Neidle CURRENT OPINION IN STRUCTURAL BIOLOGY
- Evaluation of Parameters Critical for Observing Nucleic Acids Inside LivingXenopus laevisOocytes by In-Cell NMR Spectroscopy
- (2009) Robert Hänsel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of Propeller-Type Parallel-Stranded RNA G-Quadruplexes, Formed by Human Telomeric RNA Sequences in K+Solution
- (2009) Herry Martadinata et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
- (2009) Himesh Fernando et al. NUCLEIC ACIDS RESEARCH
- A Novel Function for Fragile X Mental Retardation Protein in Translational Activation
- (2009) Elias G Bechara et al. PLOS BIOLOGY
- Early Onset Prion Disease from Octarepeat Expansion Correlates with Copper Binding Properties
- (2009) Daniel J. Stevens et al. PLoS Pathogens
- The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
- (2008) Ilaria Napoli et al. CELL
- Translational Regulation of the Human Achaete-scute Homologue-1 by Fragile X Mental Retardation Protein
- (2008) Michael Fähling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in HeLa Cell Lysates
- (2008) Steven D. Creacy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis of DNA Quadruplex Recognition by an Acridine Drug
- (2008) Nancy H. Campbell et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers
- (2008) Koji Tsumagari et al. NUCLEIC ACIDS RESEARCH
- The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer
- (2008) Marie-Cécile Didiot et al. NUCLEIC ACIDS RESEARCH
- G-quadruplexes: the beginning and end of UTRs
- (2008) Julian Leon Huppert et al. NUCLEIC ACIDS RESEARCH
- Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing
- (2008) A. Azuma-Mukai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fragile X mental retardation protein interactions with the microtubule associated protein 1B RNA
- (2008) L. Menon et al. RNA
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