Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway

Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats

(2017) Ling-Yun Wu et al.   Frontiers in Molecular Neuroscience

Biochanin-A antagonizes the interleukin-1β-induced catabolic inflammation through the modulation of NFκB cellular signaling in primary rat chondrocytes

(2016) Ji-Su Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of myeloid differentiation factor 88(MyD88) by ST2825 provides neuroprotection after experimental traumatic brain injury in mice

(2016) Hua-Sheng Zhang et al.   BRAIN RESEARCH

Inhibition of the Receptor for Advanced Glycation End-Products (RAGE) Attenuates Neuroinflammation While Sensitizing Cortical Neurons Towards Death in Experimental Subarachnoid Hemorrhage

(2016) Hua Li et al.   MOLECULAR NEUROBIOLOGY

Biochanin A Protects Against Lipopolysaccharide-Induced Damage of Dopaminergic Neurons Both In Vivo and In Vitro via Inhibition of Microglial Activation

(2016) Jun Wang et al.   NEUROTOXICITY RESEARCH

Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats

(2016) Zongduo Guo et al.   STROKE

Novel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells

(2016) Mohieldin M. Youssef  et al.   Scientific Reports

Biochanin A inhibits endothelial cell functions and proangiogenic pathways

(2015) Aditi Jain et al.   ANTI-CANCER DRUGS

Baincalein alleviates early brain injury after experimental subarachnoid hemorrhage in rats: Possible involvement of TLR4/NF-κB-mediated inflammatory pathway

(2015) Chun-xi Wang et al.   BRAIN RESEARCH

Fisetin alleviates early brain injury following experimental subarachnoid hemorrhage in rats possibly by suppressing TLR 4/NF-κB signaling pathway

(2015) Chen-hui Zhou et al.   BRAIN RESEARCH

Biochanin A Promotes Proliferation that Involves a Feedback Loop of MicroRNA-375 and Estrogen Receptor Alpha in Breast Cancer Cells

(2015) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Therapeutic efficacy of biochanin A against arsenic-induced renal and cardiac damage in rats

(2015) Abdulkadhar Mohamed Jalaludeen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment

(2015) Chenhui Zhou et al.   Journal of Neuroinflammation

Biochanin A protects against focal cerebral ischemia/reperfusion in rats via inhibition of p38-mediated inflammatory responses

(2015) Wenbo Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Biochanin A inhibits lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells

(2015) Xiaodong Ming et al.   LIFE SCIENCES

The impact of initial systemic inflammatory response after aneurysmal subarachnoid hemorrhage

(2015) Zhong Weiying et al.   Turkish Neurosurgery

Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation

(2014) Stefanie Piegholdt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biochanin A attenuates LPS-induced pro-inflammatory responses and inhibits the activation of the MAPK pathway in BV2 microglial cells

(2014) WANG-YANG WU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The role of Toll-like receptors (TLRs) in stroke

(2014) Kaveh Fadakar et al.   REVIEWS IN THE NEUROSCIENCES

Expression and cell distribution of receptor for advanced glycation end-products in the rat cortex following experimental subarachnoid hemorrhage

(2013) Hua Li et al.   BRAIN RESEARCH

Biochanin-A ameliorates behavioural and neurochemical derangements in cognitive-deficit mice for the betterment of Alzheimer’s disease

(2013) SM Biradar et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR4-mediated inflammatory pathway

(2013) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Elevated Cerebral Cortical CD24 Levels in Patients and Mice with Traumatic Brain Injury: A Potential Negative Role in Nuclear Factor Kappa B/Inflammatory Factor Pathway

(2013) Wei Li et al.   MOLECULAR NEUROBIOLOGY

Controversies and evolving new mechanisms in subarachnoid hemorrhage

(2013) Sheng Chen et al.   PROGRESS IN NEUROBIOLOGY

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis

(2012) Angela Castoldi et al.   PLoS One

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

(2012) E. Sander Connolly et al.   STROKE

Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation

(2010) Labanyamoy Kole et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Learning deficits after experimental subarachnoid hemorrhage in rats

(2010) H. Jeon et al.   NEUROSCIENCE

Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage

(2010) Gustavo Pradilla et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Relationship between sympathetic nervous activity and inflammatory response after subarachnoid hemorrhage in a perforating canine model

(2009) Cheng Gao et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Chemoprevention of mammary tumorigenesis and chemomodulation of the antioxidative enzymes and peroxidative damage in prepubertal Sprague Dawley rats by Biochanin A

(2008) Prachi Mishra et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS