HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC
出版年份 2018 全文链接
标题
HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC
作者
关键词
-
出版物
Autophagy
Volume -, Issue -, Pages 1-14
出版商
Informa UK Limited
发表日期
2018-03-22
DOI
10.1080/15548627.2018.1434471
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS- Mutant NSCLC Is Mediated via Reactivation of the ERK–p90RSK–mTOR Signaling Network
- (2017) Suman Chatterjee et al. MOLECULAR CANCER THERAPEUTICS
- The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
- (2017) Manuel Schuster et al. Scientific Reports
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia
- (2016) S. Piya et al. BLOOD
- Autophagy as a target for hematological malignancy therapy
- (2016) Zhiwu Dong et al. BLOOD REVIEWS
- Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells
- (2016) WEI HE et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
- (2016) Gian-Luca McLelland et al. JOURNAL OF CELL BIOLOGY
- The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
- (2016) Kotaro Tsuboyama et al. SCIENCE
- Multiple Roles of the Small GTPase Rab7
- (2016) Flora Guerra et al. Cells
- Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells
- (2015) Weilong Yao et al. CANCER LETTERS
- Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non–Small-Cell Lung Cancer Cells
- (2015) Jia-Tao Liu et al. Clinical Lung Cancer
- A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division
- (2015) Kohei Arasaki et al. DEVELOPMENTAL CELL
- Applications of flow cytometry for measurement of autophagy
- (2015) Alik Demishtein et al. METHODS
- Hsp90: Breaking the Symmetry
- (2015) Matthias P. Mayer et al. MOLECULAR CELL
- Resistance to HSP90 inhibition involving loss of MCL1 addiction
- (2015) S Busacca et al. ONCOGENE
- Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90
- (2015) Edgar E. Boczek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
- (2015) Christina H. Eng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hsp90 interaction with clients
- (2015) G. Elif Karagöz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines
- (2015) Liangkun You et al. Oncotarget
- Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells
- (2015) Hui-Mei Wu et al. Scientific Reports
- Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent
- (2014) Michael J Morgan et al. Autophagy
- Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers
- (2014) Sylvain Lefort et al. Autophagy
- Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
- (2014) MASAKI MORI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The Biogenesis of Lysosomes and Lysosome-Related Organelles
- (2014) J. P. Luzio et al. Cold Spring Harbor Perspectives in Biology
- Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
- (2014) G. Karsli-Uzunbas et al. Cancer Discovery
- Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib
- (2014) Hongming Pan et al. Scientific Reports
- Autophagy-Mediated Tumor Promotion
- (2013) Jessie Yanxiang Guo et al. CELL
- Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
- (2013) Jing Zhou et al. CELL RESEARCH
- A Multicenter Phase II Study of Ganetespib Monotherapy in Patients with Genotypically Defined Advanced Non-Small Cell Lung Cancer
- (2013) M. A. Socinski et al. CLINICAL CANCER RESEARCH
- A Complex between Atg7 and Caspase-9
- (2013) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of HSP90 molecular chaperones: moving into the clinic
- (2013) Rocio Garcia-Carbonero et al. LANCET ONCOLOGY
- The HSP90 Inhibitor NVP-AUY922 Potently Inhibits Non-Small Cell Lung Cancer Growth
- (2013) E. B. Garon et al. MOLECULAR CANCER THERAPEUTICS
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
- (2013) X Sui et al. Cell Death & Disease
- Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
- (2012) R. Ramakrishnan et al. CANCER RESEARCH
- The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
- (2012) Eisuke Itakura et al. CELL
- Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non-Small Cell Lung Cancer
- (2012) T. Shimamura et al. CLINICAL CANCER RESEARCH
- Inhibiting HSP90 to Treat Cancer: A Strategy in Evolution
- (2012) L. Whitesell et al. CURRENT MOLECULAR MEDICINE
- Targeting KRAS-Mutant Non-Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib
- (2012) J. Acquaviva et al. MOLECULAR CANCER THERAPEUTICS
- Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors
- (2011) Thomas De Raedt et al. CANCER CELL
- SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells
- (2011) Kai-Sheng Liu et al. CANCER LETTERS
- Autophagic degradation of active caspase-8
- (2010) Wen Hou et al. Autophagy
- Involvement of caspase-9 in autophagy-mediated cell survival pathway
- (2010) Hyo-Soon Jeong et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Deregulation of Mitochondrial Membrane Potential by Mitochondrial Insertion of Granzyme B and Direct Hax-1 Cleavage
- (2010) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Mitochondrial Apoptotic Events by p53-mediated Disruption of Complexes between Antiapoptotic Bcl-2 Members and Bim
- (2010) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Geldanamycin and its anti-cancer activities
- (2009) Yayoi Fukuyo et al. CANCER LETTERS
- Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells
- (2008) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now