miR-124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1

Knockdown of UHRF1 by Lentivirus-mediated shRNA Inhibits Ovarian Cancer Cell Growth

(2015) Feng Yan et al.   Asian Pacific Journal of Cancer Prevention

Low mir-372 expression correlates with poor prognosis and tumor metastasis in hepatocellular carcinoma

(2015) Gang Wu et al.   BMC CANCER

miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1

(2015) Henriett Butz et al.   Oncotarget

Regulation and Methylation of Tumor Suppressor MiR-124 by Androgen Receptor in Prostate Cancer Cells

(2015) Mingliang Chu et al.   PLoS One

MiR-124 retards bladder cancer growth by directly targeting CDK4

(2014) Ting Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

UHRF1 Overexpression Drives DNA Hypomethylation and Hepatocellular Carcinoma

(2014) Raksha Mudbhary et al.   CANCER CELL

MiR-124 represses vasculogenic mimicry and cell motility by targeting amotL1 in cervical cancer cells

(2014) Hai-Ying Wan et al.   CANCER LETTERS

Epigenetic repression of regulator of G-protein signaling 2 by ubiquitin-like with PHD and ring-finger domain 1 promotes bladder cancer progression

(2014) Liang Ying et al.   FEBS Journal

MicroRNA miR-124 Controls the Choice between Neuronal and Astrocyte Differentiation by Fine-tuning Ezh2 Expression

(2014) Wen Hao Neo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras

(2014) Zhumei Shi et al.   NEURO-ONCOLOGY

Upregulated UHRF1 Promotes Bladder Cancer Cell Invasion by Epigenetic Silencing of KiSS1

(2014) Yu Zhang et al.   PLoS One

Increasing role of UHRF1 in the reading and inheritance of the epigenetic code as well as in tumorogenesis

(2013) Christian Bronner et al.   BIOCHEMICAL PHARMACOLOGY

Alterations of DNA methylome in human bladder cancer

(2013) Ahmad Besaratinia et al.   Epigenetics

MicroRNA-124-3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1

(2013) Xianglai Xu et al.   Journal of Translational Medicine

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

(2013) P Wang et al.   ONCOGENE

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression

(2012) L Sabatino et al.   ONCOGENE

The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression

(2012) F Babbio et al.   ONCOGENE

UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis

(2011) Amy L. Tien et al.   BIOCHEMICAL JOURNAL

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

(2011) Mahmoud Alhosin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

(2010) Saskia M Wilting et al.   Molecular Cancer

Current and Potential Anticancer Drugs Targeting Members of the UHRF1 Complex Including Epigenetic Modifiers

(2010) Motoko Unoki   Recent Patents on Anti-Cancer Drug Discovery

UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer

(2009) M Unoki et al.   BRITISH JOURNAL OF CANCER

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE