MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

(2015) William H. Chappell et al.   Oncotarget

Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2-IGF2BP2 Pathway

(2013) Z. Li et al.   CANCER RESEARCH

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

(2013) Jun Wei et al.   CANCER RESEARCH

Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: Implications for the treatment of human liver cancer

(2013) Chunmei Wang et al.   CELL CYCLE

Characteristics of Lung Cancers Harboring NRAS Mutations

(2013) K. Ohashi et al.   CLINICAL CANCER RESEARCH

MiR-139 Inhibits Mcl-1 Expression and Potentiates TMZ-Induced Apoptosis in Glioma

(2013) Rui-Yan Li et al.   CNS Neuroscience & Therapeutics

Targeting the RAS oncogene

(2013) Asami Takashima et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

(2013) Julie Halkein et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN

(2013) X.-R. Wang et al.   NEURO-ONCOLOGY

microRNA-124 Inhibits Migration and Invasion by Down-Regulating ROCK1 in Glioma

(2013) Liwen An et al.   PLoS One

Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo

(2013) C. Posch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small GTPase R-Ras Regulates Integrity and Functionality of Tumor Blood Vessels

(2012) Junko Sawada et al.   CANCER CELL

MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF

(2012) Chao Zou et al.   CELL CYCLE

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

(2012) Chiara Sandri et al.   CELL RESEARCH

Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders

(2012) Justin M. Long et al.   EXPERIMENTAL NEUROLOGY

miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1

(2012) Daniela Cimino et al.   FASEB JOURNAL

A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion

(2012) Heidi G. Møller et al.   MOLECULAR NEUROBIOLOGY

MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion

(2012) Qian-Qian Zhang et al.   NEURO-ONCOLOGY

Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells

(2012) Ming-Fei Lang et al.   PLoS One

MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol

(2011) Zhiyuan Han et al.   CARCINOGENESIS

Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide

(2011) G. Prasad et al.   NEURO-ONCOLOGY

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic   cell death

(2011) Q. Ruan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma

(2010) Libero Santarpia et al.   CANCER

Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration

(2010) Vipin Yadav et al.   MOLECULAR CARCINOGENESIS

R-Ras Regulates Migration through an Interaction with Filamin A in Melanoma Cells

(2010) Joanna E. Gawecka et al.   PLoS One

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A PCR-based platform for microRNA expression profiling studies

(2009) X. Wang   RNA