Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men

Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

(2014) D. Rebourcet et al.   DEVELOPMENT

Estrogen promotes Leydig cell engulfment by macrophages in male infertility

(2014) Wanpeng Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting of GFP-Cre to the Mouse Cyp11a1 Locus Both Drives Cre Recombinase Expression in Steroidogenic Cells and Permits Generation of Cyp11a1 Knock Out Mice

(2014) Laura O'Hara et al.   PLoS One

Aging and Luteinizing Hormone Effects on Reactive Oxygen Species Production and DNA Damage in Rat Leydig Cells1

(2013) Matthew C. Beattie et al.   BIOLOGY OF REPRODUCTION

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

(2013) K. Y. Lee et al.   DIABETES

Sertoli Cell Androgen Receptor Expression Regulates Temporal Fetal and Adult Leydig Cell Differentiation, Function, and Population Size

(2013) Rasmani Hazra et al.   ENDOCRINOLOGY

Late-Onset Hypogonadism and Mortality in Aging Men

(2013) S. R. Pye et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Phenotype and steroidogenic potential of PDGFRα-positive rat neonatal peritubular cells

(2013) Luise Landreh et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin-Like 3 Signaling Is Important for Testicular Descent but Dispensable for Spermatogenesis and Germ Cell Survival in Adult Mice1

(2012) Zaohua Huang et al.   BIOLOGY OF REPRODUCTION

Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis

(2012) Kerry J. McInnes et al.   DIABETES

Androgen insensitivity syndrome

(2012) Ieuan A Hughes et al.   LANCET

Contribution of Leydig and Sertoli Cells to Testosterone Production in Mouse Fetal Testes

(2012) Yuichi Shima et al.   MOLECULAR ENDOCRINOLOGY

Transcriptomine, a web resource for nuclear receptor signaling transcriptomes

(2012) Scott A. Ochsner et al.   PHYSIOLOGICAL GENOMICS

KATNAL1 Regulation of Sertoli Cell Microtubule Dynamics Is Essential for Spermiogenesis and Male Fertility

(2012) Lee B. Smith et al.   PLoS Genetics

Anterior prostate epithelial AR inactivation modifies estrogen receptor expression and increases estrogen sensitivity

(2011) Ulla Simanainen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Smooth Muscle Cell-Specific Knockout of Androgen Receptor: A New Model for Prostatic Disease

(2011) Michelle Welsh et al.   ENDOCRINOLOGY

Estimation of Estradiol in Mouse Serum Samples: Evaluation of Commercial Estradiol Immunoassays

(2011) Daniel J. Haisenleder et al.   ENDOCRINOLOGY

Androgen receptor signalling in peritubular myoid cells is essential for normal differentiation and function of adult Leydig cells

(2011) M. Welsh et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

The Relationship Between Anogenital Distance and Reproductive Hormone Levels in Adult Men

(2011) Michael L. Eisenberg et al.   JOURNAL OF UROLOGY

Intrinsic disorder in the androgen receptor: identification, characterisation and drugability

(2011) Iain J. McEwan   Molecular BioSystems

Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats

(2011) Victoria Tyndall et al.   REPRODUCTION

Androgens and cardiovascular disease

(2011) Bu B Yeap   Current Opinion in Endocrinology Diabetes and Obesity

Stem cells in mammalian spermatogenesis

(2010) Shosei Yoshida   DEVELOPMENT GROWTH & DIFFERENTIATION

Deletion of Androgen Receptor in the Smooth Muscle of the Seminal Vesicles Impairs Secretory Function and Alters Its Responsiveness to Exogenous Testosterone and Estradiol

(2010) Michelle Welsh et al.   ENDOCRINOLOGY

Androgen Receptor Expression in the Caput Epididymal Epithelium Is Essential for Development of the Initial Segment and Epididymal Spermatozoa Transit

(2010) Laura O'Hara et al.   ENDOCRINOLOGY

Ectopic recombination in the central and peripheral nervous system byaP2/FABP4-Cremice: Implications for metabolism research

(2010) Katrin Martens et al.   FEBS LETTERS

Androgen Action via Testicular Arteriole Smooth Muscle Cells Is Important for Leydig Cell Function, Vasomotion and Testicular Fluid Dynamics

(2010) Michelle Welsh et al.   PLoS One

Good planning and serendipity: exploiting the Cre/Lox system in the testis

(2010) Lee Smith   REPRODUCTION

New Insights into the Role of Androgens in Wolffian Duct Stabilization in Male and Female Rodents

(2009) Michelle Welsh et al.   ENDOCRINOLOGY

Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development

(2009) Amanda J. Drake et al.   ENDOCRINOLOGY

Androgen action via testicular peritubular myoid cells is essential for male fertility

(2009) Michelle Welsh et al.   FASEB JOURNAL

Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses

(2009) K. Raskin et al.   JOURNAL OF NEUROSCIENCE

The role of testosterone in the metabolic syndrome: A review

(2009) Farid Saad et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Leydig cells: From stem cells to aging

(2009) Haolin Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Androgen-Responsive Gene Database: Integrated Knowledge on Androgen-Responsive Genes

(2009) Mei Jiang et al.   MOLECULAR ENDOCRINOLOGY

Adverse effects associated with persistent stimulation of Leydig cells with hCG in vitro

(2009) Archana Aggarwal et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Low Testosterone and the Association With Type 2 Diabetes

(2008) JoAnne B. Farrell et al.   DIABETES EDUCATOR

Antagonistic Effects of Testosterone and the Endocrine Disruptor Mono-(2-Ethylhexyl) Phthalate onINSL3Transcription in Leydig Cells

(2008) Éric Laguë et al.   ENDOCRINOLOGY

Hyperleptinemia without Obesity in Male Mice Lacking Androgen Receptor in Adipose Tissue

(2008) I-Chen Yu et al.   ENDOCRINOLOGY

Inverse Association of Testosterone and the Metabolic Syndrome in Men Is Consistent across Race and Ethnic Groups

(2008) Varant Kupelian et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Leydig cell aging and the mechanisms of reduced testosterone synthesis

(2008) Andrew S. Midzak et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Low Serum Testosterone and Mortality in Older Men

(2007) Gail A. Laughlin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM