Article
Chemistry, Organic
Pablo Morrone-Pozzuto, Maria Laura Uhrig, Rosalia Agusti
Summary: This study investigated the interaction between two important activities on the surface of Trypanosoma cruzi, the agent of Chagas disease. The researchers synthesized a trisaccharide and two isomeric tetrasaccharides to study the interaction between the trans-sialidase (TcTS) and lytic antibodies. The results showed that these synthetic structures were good acceptors of sialic acid in the reaction catalyzed by TcTS.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Microbiology
Fatma Abdelrahman, Nouran Rezk, Mohamed S. Fayez, Mohamed Abdelmoteleb, Reham Atteya, Mohamed Elhadidy, Ayman El-Shibiny
Summary: This study isolated and characterized three novel bacteriophages against E. coli from sewage water. The phages had a genome size of 44,776 bp and belonged to the Siphoviridae family. They showed good tolerance to a broad range of pH and temperature.
Article
Multidisciplinary Sciences
Ahmed R. Elbestawy, Hany F. Ellakany, Hatem S. Abd El-Hamid, Madiha S. Ibrahim, Ahmed R. Gado, Nagwa S. Mustafa, Ihab M. Moussa, Khalid S. Al-Maary, Dalia S. Al-Sarar, Hanan O. Alshammari, Turki M. Dawoud, Hassan A. Hemeg, Hussein M. Galal
Summary: This study evaluated the cross-protection ability of live attenuated E. coli vaccine against heterologous APEC serotypes, showing significant protection but subtle differences in clinical signs, post-mortem lesions, mortality rates, E. coli re-isolation, histopathological examination, final body weight, and feed conversion ratio.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Infectious Diseases
Yitao Duan, Shuangqing Liu, Yuting Gao, Peng Zhang, Daqing Mao, Yi Luo
Summary: Macrolides can activate the transcription of the msr(E)-mph(E) operon through the involvement of HNS and CRP. The operon was found to exist widely in diverse species of bacteria, with Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis being the main carriers. These bacteria were primarily isolated from human clinical samples and had a wide geographical distribution.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Physics, Multidisciplinary
Gaspard Junot, Thierry Darnige, Anke Lindner, Vincent A. Martinez, Jochen Arlt, Angela Dawson, Wilson C. K. Poon, Harold Auradou, Eric Clement
Summary: This article investigates the movement and biofilm formation of motile bacteria on surfaces. Using a novel tracking technique, the researchers observed surface residence and escape behaviors. A motility model was proposed to explain the findings and provide new insights into surface trapping efficiency.
PHYSICAL REVIEW LETTERS
(2022)
Article
Immunology
Veronicah M. M. Chuchu, Nyamai Mutono, Philet Bichanga, Philip M. M. Kitala, Daniel Ksee, Mathew Muturi, Athman Mwatondo, Carolyne Nasimiyu, Lawrence Akunga, Amine Amiche, Katie Hampson, Samuel M. M. Thumbi
Summary: Sending SMS reminders to bite patients in rural eastern Kenya can improve their adherence to scheduled rabies prophylaxis, reduce treatment delay, alleviate financial burden, and contribute to rabies control and elimination strategies.
Article
Engineering, Environmental
Eri van Heijnsbergen, Gunnar Niebaum, Volker Laemmchen, Alicia Borneman, Lucia Hernandez Leal, Joerg Klasmeier, Heike Schmitt
Summary: This study investigated the occurrence of Escherichia coli and antibiotic-resistant E. coli in the Dutch-German transboundary catchment of the Vecht River. The study found a higher proportion of ESBL-EC in German wastewater treatment plants compared to Dutch plants. The modeling approach predicted E. coli concentrations to be below the threshold for good bathing water quality.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Neurosciences
Mingyao You, Ping Yuan, Liangqian Li, Baoduo Li, Zijun Peng, Hongbei Xu
Summary: This study used Mendelian randomization to investigate the causal link between COVID-19 and epilepsy, finding that genetic liability to COVID-19 infection, hospitalization, and severity had a causal effect on epilepsy. However, no evidence was found to support epilepsy contributing to COVID-19. Gene analysis identified overlapping genes between COVID-19 and epilepsy.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Computer Science, Artificial Intelligence
Sajad Esfandyari, Vahid Rafe
Summary: Covering array generation is an important branch of combinatorial testing with various algorithms available. The challenge lies in generating arrays with the minimum number of test cases for large systems in appropriate run-time. Different generation strategies have their own strengths and weaknesses in terms of performance and efficiency, making it difficult to find an optimal strategy that excels in both aspects.
Article
Microbiology
Chris Kenyon, Zina Gestels, Thibaut Vanbaelen, Said Abdellati, Dorien van den Bossche, Irith De Baetselier, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil
Summary: This study evaluated the impact of doxycycline PEP on resistance in Klebsiella pneumoniae and found that it can select for resistance to doxycycline, ceftriaxone, and ciprofloxacin in a G. mellonella model. The emergence of ramR mutations in K. pneumoniae was similar to those seen in circulating strains. These findings suggest the need for further assessment of the effect of doxycycline PEP on resistance induction in a broader range of bacterial species.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Automation & Control Systems
Yu Huang, Chengyong Wang, Feng Ding, Yang Yang, Tao Zhang, Xiaolin He, Lijuan Zheng, Naitao Li
Summary: Plasma electrolytic polishing (PeP) is an innovative technology used to achieve metal surfaces with low roughness and high gloss. Its advantages of high efficiency, no structural selectivity, and low pollution have attracted significant attention. This paper introduces the basic principles, characteristics, control parameters, and electrolyte jet polishing methods of PeP technology, providing insights into its prospects.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Marcin Smialek, Joanna Kowalczyk, Andrzej Koncicki
Summary: Escherichia coli infections are a major cause of economic loss in the poultry industry, and vaccination against E. coli has a positive impact on bird health without affecting vaccination efficacy against other poultry diseases. The study conducted three independent experiments demonstrating that vaccination reduces E. coli population counts and increases antibiotic susceptibility in field isolates without impacting vaccination against another major poultry disease, TRT.
Article
Multidisciplinary Sciences
Kazuki Kato, Sae Okazaki, Cian Schmitt-Ulms, Kaiyi Jiang, Wenyuan Zhou, Junichiro Ishikawa, Yukari Isayama, Shungo Adachi, Tomohiro Nishizawa, Kira S. Makarova, Eugene V. Koonin, Omar O. Abudayyeh, Jonathan S. Gootenberg, Hiroshi Nishimasu
Summary: The type III-E CRISPR-Cas7-11 effector can catalyze crRNA-guided RNA cleavage by binding crRNA and Csx29, and the binding of tgRNA induces conformational changes in Csx29. Csx29 cleaves Csx30 through a tgRNA-dependent pathway, resulting in the generation of toxic protein fragments and growth arrest, which is regulated by Csx31. Csx30 modulates the cellular response to infection by binding Csx31 and the associated sigma factor RpoE. Additionally, the Cas7-11-Csx29-Csx30 system has been engineered for programmable RNA sensing in mammalian cells.
Article
Microbiology
Camille Chagneau, Clemence Massip, Nadege Bossuet-Greif, Christophe Fremez, Jean-Paul Motta, Ayaka Shima, Celine Besson, Pauline Le Faouder, Nicolas Cenac, Marie-Paule Roth, Helene Coppin, Maxime Fontanie, Patricia Martin, Jean-Philippe Nougayrede, Eric Oswald
Summary: This study found the presence of the genotoxin Colibactin in the urine of patients with urinary tract infections, and demonstrated its genotoxicity in bladder cells. This discovery raises the hypothesis of a potential link between urinary tract infections and bladder cancer.
Article
Chemistry, Multidisciplinary
Karen J. Cardenas-Martinez, Andrea C. Barragan-Cardenas, Manuela de la Rosa-Arbelaez, Claudia M. Parra-Giraldo, Alejandra Ochoa-Zarzosa, Joel E. Lopez-Meza, Zuly J. Rivera-Monroy, Ricardo Fierro-Medina, Javier E. Garcia-Castaneda
Summary: Anticancer peptides are promising alternative treatments for cancer due to their potency, selectivity, and low toxicity. This study developed modifications to a peptide sequence to increase its anticancer activity and demonstrated lower toxicity. The modified peptides showed activity against Caco-2 and HT-29 cell lines and decreased IC50 values in Caco-2 cells.
Article
Biotechnology & Applied Microbiology
Jingyu Wang, Kechun Zhang
METABOLIC ENGINEERING
(2015)
Article
Engineering, Chemical
Tong Lin, Xue Bai, Yidan Hu, Bingzhi Li, Ying-Jin Yuan, Hao Song, Yun Yang, Jingyu Wang
Article
Biotechnology & Applied Microbiology
Jilong Wang, Suthamat Niyompanich, Yi-Shu Tai, Jingyu Wang, Wenqin Bai, Prithviraj Mahida, Tuo Gao, Kechun Zhang
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2016)
Article
Green & Sustainable Science & Technology
Yaxin Sang, Qian Xue, Zishang Bai, Jingyu Wang, Limin Cao
JOURNAL OF RENEWABLE AND SUSTAINABLE ENERGY
(2016)
Article
Biotechnology & Applied Microbiology
Wenqin Bai, Yi-Shu Tai, Jingyu Wang, Jilong Wang, Pooja Jambunathan, Kevin J. Fox, Kechun Zhang
METABOLIC ENGINEERING
(2016)
Article
Biochemistry & Molecular Biology
Yi-Shu Tai, Mingyong Xiong, Pooja Jambunathan, Jingyu Wang, Jilong Wang, Cole Stapleton, Kechun Zhang
NATURE CHEMICAL BIOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
Xinyuan Zhang, Jingyu Wang, Weiwei Zhang, Jun yan Hou, Wei Xiao, Limin Cao
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2018)
Article
Biotechnology & Applied Microbiology
Jing-Jing Liu, Wen-Tao Ding, Guo-Chang Zhang, Jing-Yu Wang
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2011)
Article
Biotechnology & Applied Microbiology
Jingyu Wang, Wen Liu, Wentao Ding, Guochang Zhang, Jingjing Liu
BIOTECHNOLOGY LETTERS
(2013)
Article
Engineering, Chemical
Duan Yunxia, Chen Tao, Chen Xun, Wang Jingyu, Zhao Xueming
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2010)
Article
Biotechnology & Applied Microbiology
Mingyong Xiong, Jingyu Wang
FEMS YEAST RESEARCH
(2010)
Article
Biotechnology & Applied Microbiology
Limin Cao, Xingliang Tang, Xinyuan Zhang, Jingtao Zhang, Xuelei Tian, Jingyu Wang, Mingyong Xiong, Wei Xiao
METABOLIC ENGINEERING
(2014)
Article
Microbiology
Jian Zha, Meng-Long Hu, Ming-Hua Shen, Bing-Zhi Li, Jing-Yu Wang, Ying-Jin Yuan
FRONTIERS IN MICROBIOLOGY
(2012)
Article
Chemistry, Physical
Charles S. Spanjers, Deborah K. Schneiderman, Jay Z. Wang, Jingyu Wang, Marc A. Hillmyer, Kechun Zhang, Paul J. Dauenhauer