Identification and metabolomic analysis of chemical elicitors for tacrolimus accumulation in Streptomyces tsukubaensis
出版年份 2018 全文链接
标题
Identification and metabolomic analysis of chemical elicitors for tacrolimus accumulation in Streptomyces tsukubaensis
作者
关键词
Tacrolimus, Chemical elicitors, Metabolomic network, <em class=EmphasisTypeItalic >S. tsukubaensis</em>
出版物
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-06-25
DOI
10.1007/s00253-018-9177-0
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Combining metabolomics and network analysis to improve tacrolimus production in Streptomyces tsukubaensis using different exogenous feedings
- (2017) Cheng Wang et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Insights into the metabolic mechanism of rapamycin overproduction in the shikimate-resistant Streptomyces hygroscopicus strain UV-II using comparative metabolomics
- (2017) Huiyan Geng et al. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
- Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes
- (2016) María Ordóñez-Robles et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- FkbN and Tcs7 are pathway-specific regulators of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis L19
- (2016) Xiao-Sheng Zhang et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Involvement of small heat shock proteins, trehalose, and lipids in the thermal stress management in Schizosaccharomyces pombe
- (2015) Attila Glatz et al. CELL STRESS & CHAPERONES
- The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects
- (2015) Yeon Hee Ban et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Identification and mechanism analysis of chemical modulators enhancing astaxanthin accumulation in Haematococcus pluvialis
- (2015) Xinheng Yu et al. Algal Research-Biomass Biofuels and Bioproducts
- Metabolomic and network analysis of astaxanthin-producing Haematococcus pluvialis under various stress conditions
- (2014) Yingxue Su et al. BIORESOURCE TECHNOLOGY
- Metabolomic analysis of the salt-sensitive mutants reveals changes in amino acid and fatty acid composition important to long-term salt stress in Synechocystis sp. PCC 6803
- (2014) Jiangxin Wang et al. FUNCTIONAL & INTEGRATIVE GENOMICS
- Metabolomic Analysis Reveals Mechanism of Antioxidant Butylated Hydroxyanisole on Lipid Accumulation in Crypthecodinium cohnii
- (2014) Xiao Sui et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Enhancement of ascomycin production in Streptomyces hygroscopicus var. ascomyceticus by combining resin HP20 addition and metabolic profiling analysis
- (2014) Haishan Qi et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies
- (2014) Wenjie Du et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506)
- (2013) Carlos Barreiro et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Enhanced FK506 production inStreptomyces tsukubaensisby rational feeding strategies based on comparative metabolic profiling analysis
- (2013) Menglei Xia et al. BIOTECHNOLOGY AND BIOENGINEERING
- Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies
- (2013) Di Huang et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Triggers and cues that activate antibiotic production by actinomycetes
- (2013) Hua Zhu et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Activating secondary metabolism with stress and chemicals
- (2013) Vanessa Yoon et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Characterization of FK506 Biosynthetic Intermediates Involved in Post-PKS Elaboration
- (2013) Yeon Hee Ban et al. JOURNAL OF NATURAL PRODUCTS
- Global Metabolomic and Network analysis of Escherichia coli Responses to Exogenous Biofuels
- (2013) Jiangxin Wang et al. JOURNAL OF PROTEOME RESEARCH
- Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement
- (2013) Di Huang et al. Microbial Cell Factories
- Roles offkbNin Positive Regulation andtcs7in Negative Regulation of FK506 Biosynthesis in Streptomyces sp. Strain KCTC 11604BP
- (2012) SangJoon Mo et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Taxonomy and chemically semi-defined media for the analysis of the tacrolimus producer ‘Streptomyces tsukubaensis’
- (2012) Miriam Martínez-Castro et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis
- (2012) Dušan Goranovič et al. BMC MICROBIOLOGY
- Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis
- (2012) Jadwiga Turło et al. ENZYME AND MICROBIAL TECHNOLOGY
- MetPA: a web-based metabolomics tool for pathway analysis and visualization
- (2010) J. Xia et al. BIOINFORMATICS
- Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor
- (2009) SangJoon Mo et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Regulation of tacrolimus production by altering primary source of carbons and amino acids
- (2009) B.P. Singh et al. LETTERS IN APPLIED MICROBIOLOGY
- Integrating multiple 'omics' analysis for microbial biology: application and methodologies
- (2009) W. Zhang et al. MICROBIOLOGY-SGM
- Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs
- (2009) Edmund I. Graziani NATURAL PRODUCT REPORTS
- Biosynthesis of polyketide synthase extender units
- (2008) Yolande A. Chan et al. NATURAL PRODUCT REPORTS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started