Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract

Impact of the 13-valent pneumococcal conjugate vaccine on Streptococcus pneumoniae multiple serotype carriage

(2016) Carina Valente et al.   VACCINE

PSGL-1 on Leukocytes is a Critical Component of the Host Immune Response against Invasive Pneumococcal Disease

(2016) Elisa Ramos-Sevillano et al.   PLoS Pathogens

PL3 Amidase, a Tailor-made Lysin Constructed by Domain Shuffling with Potent Killing Activity against Pneumococci and Related Species

(2016) Blas Blázquez et al.   Frontiers in Microbiology

Streptococcus pneumoniae colonisation in children and adolescents with asthma: impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine

(2015) Susanna Esposito et al.   BMC INFECTIOUS DISEASES

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae

(2015) R. Diez-Martinez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Spectrum and Management of Complement Immunodeficiencies (Excluding Hereditary Angioedema) Across Europe

(2015) A. J. Turley et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Macrolides Promote CCL2-Mediated Macrophage Recruitment and Clearance of Nasopharyngeal Pneumococcal Colonization in Mice

(2015) Naoki Iwanaga et al.   JOURNAL OF INFECTIOUS DISEASES

Decline in Pneumococcal Nasopharyngeal Carriage of Vaccine Serotypes After the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Children in Atlanta, Georgia

(2015) Ankita P. Desai et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Streptococcus pneumoniaepharyngeal colonization in school-age children and adolescents with cancer

(2015) Nicola Principi et al.   Human Vaccines & Immunotherapeutics

Risk of Pneumococcal Disease in Children With Chronic Medical Conditions in the Era of Pneumococcal Conjugate Vaccine

(2014) Stephen I. Pelton et al.   CLINICAL INFECTIOUS DISEASES

Pleiotropic Effects of Cell Wall Amidase LytA on Streptococcus pneumoniae Sensitivity to the Host Immune Response

(2014) Elisa Ramos-Sevillano et al.   INFECTION AND IMMUNITY

Airway Microbiome Dynamics in Exacerbations of Chronic Obstructive Pulmonary Disease

(2014) Y. J. Huang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Rates of Pneumococcal Disease in Adults With Chronic Medical Conditions

(2014) Kimberly M. Shea et al.   Open Forum Infectious Diseases

Improving the Lethal Effect of Cpl-7, a Pneumococcal Phage Lysozyme with Broad Bactericidal Activity, by Inverting the Net Charge of Its Cell Wall-Binding Module

(2013) Roberto Díez-Martínez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lysins: the arrival of pathogen-directed anti-infectives

(2013) M. Pastagia et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Macrolides and β-Lactam Antibiotics Enhance C3b Deposition on the Surface of Multidrug-Resistant Streptococcus pneumoniae Strains by a LytA Autolysin-Dependent Mechanism

(2012) Elisa Ramos-Sevillano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Human Milk Protein-Lipid Complex HAMLET Sensitizes Bacterial Pathogens to Traditional Antimicrobial Agents

(2012) Laura R. Marks et al.   PLoS One

In VitroDestruction of Streptococcus pneumoniae Biofilms with Bacterial and Phage Peptidoglycan Hydrolases

(2011) Mirian Domenech et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Susceptibilities and Serotypes of Streptococcus pneumoniae Isolates from Elderly Patients with Pneumonia and Acute Exacerbation of Chronic Obstructive Pulmonary Disease

(2011) Emilio Pérez-Trallero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nasopharyngeal Colonization and Invasive Disease Are Enhanced by the Cell Wall Hydrolases LytB and LytC of Streptococcus pneumoniae

(2011) Elisa Ramos-Sevillano et al.   PLoS One

Impact of Cotrimoxazole on Carriage and Antibiotic Resistance of Streptococcus pneumoniae and Haemophilus influenzae in HIV-Infected Children in Zambia

(2010) D. M. Mwenya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Serotypes and genotypes of Streptococcus pneumoniae causing pneumonia and acute exacerbations in patients with chronic obstructive pulmonary disease

(2010) Arnau Domenech et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evidence for a non-replicative intracellular stage of nontypable Haemophilus influenzae in epithelial cells

(2010) P. Morey et al.   MICROBIOLOGY-SGM

Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia*

(2009) Martin Witzenrath et al.   CRITICAL CARE MEDICINE

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

(2009) Tom van der Poll et al.   LANCET

Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

(2009) Katherine L O'Brien et al.   LANCET

Antibiotic susceptibility and molecular epidemiology of nasopharyngeal pneumococci from Spanish children

(2008) D. Sánchez-Tatay et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacteriophage lysins as effective antibacterials

(2008) Vincent A Fischetti   CURRENT OPINION IN MICROBIOLOGY

New evidence of risk factors for community-acquired pneumonia: a population-based study

(2008) J. Almirall et al.   EUROPEAN RESPIRATORY JOURNAL

Phage Lytic Enzyme Cpl‐1 for Antibacterial Therapy in Experimental Pneumococcal Meningitis

(2008) Denis Grandgirard et al.   JOURNAL OF INFECTIOUS DISEASES

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

(2008) Sanjay Sethi et al.   NEW ENGLAND JOURNAL OF MEDICINE