Pleiotropic Effects of Cell Wall Amidase LytA on Streptococcus pneumoniae Sensitivity to the Host Immune Response

Binding ofStreptococcus pneumoniaeEndopeptidase O (PepO) to Complement Component C1q Modulates the Complement Attack and Promotes Host Cell Adherence

(2014) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

(2014) P. Mellroth et al.   mBio

Biofilm Formation Avoids Complement Immunity and Phagocytosis of Streptococcus pneumoniae

(2013) Mirian Domenech et al.   INFECTION AND IMMUNITY

Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin

(2013) M. Alcorlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrolides and β-Lactam Antibiotics Enhance C3b Deposition on the Surface of Multidrug-Resistant Streptococcus pneumoniae Strains by a LytA Autolysin-Dependent Mechanism

(2012) Elisa Ramos-Sevillano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion

(2012) V. Agarwal et al.   JOURNAL OF IMMUNOLOGY

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

(2012) Youssif M. Ali et al.   PLoS Pathogens

Minimization of Bacterial Size Allows for Complement Evasion and Is Overcome by the Agglutinating Effect of Antibody

(2011) Ankur B. Dalia et al.   Cell Host & Microbe

Nasopharyngeal Colonization and Invasive Disease Are Enhanced by the Cell Wall Hydrolases LytB and LytC of Streptococcus pneumoniae

(2011) Elisa Ramos-Sevillano et al.   PLoS One

Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopy

(2011) Martin Alcorlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three Surface Exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, Promote Resistance to Opsonophagocytic Killing by Human Neutrophils

(2010) A. B. Dalia et al.   INFECTION AND IMMUNITY

Evidence for a non-replicative intracellular stage of nontypable Haemophilus influenzae in epithelial cells

(2010) P. Morey et al.   MICROBIOLOGY-SGM

Vancomycin tolerance in clinical and laboratory Streptococcus pneumoniae isolates depends on reduced enzyme activity of the major LytA autolysin or cooperation between CiaH histidine kinase and capsular polysaccharide

(2010) Miriam Moscoso et al.   MOLECULAR MICROBIOLOGY

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Versatility of the capsular genes during biofilm formation byStreptococcus pneumoniae

(2009) Mirian Domenech et al.   ENVIRONMENTAL MICROBIOLOGY

Streptococcus pneumoniae Autolysis Prevents Phagocytosis and Production of Phagocyte-Activating Cytokines

(2009) A. Martner et al.   INFECTION AND IMMUNITY

The Streptococcus pneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms

(2009) C. Hyams et al.   INFECTION AND IMMUNITY

The Effects of PspC on Complement-Mediated Immunity to Streptococcus pneumoniae Vary with Strain Background and Capsular Serotype

(2009) J. Yuste et al.   INFECTION AND IMMUNITY

Pneumolysin Localizes to the Cell Wall of Streptococcus pneumoniae

(2009) K. E. Price et al.   JOURNAL OF BACTERIOLOGY

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

(2009) A. Dieudonne-Vatran et al.   JOURNAL OF IMMUNOLOGY

Human Neutrophils Kill Streptococcus pneumoniae via Serine Proteases

(2009) A. J. Standish et al.   JOURNAL OF IMMUNOLOGY

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

(2009) Tom van der Poll et al.   LANCET

Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

(2009) Katherine L O'Brien et al.   LANCET

Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H

(2008) Abiodun D. Ogunniyi et al.   FASEB JOURNAL

Antibody to the Type 3 Capsule Facilitates Immune Adherence of Pneumococci to Erythrocytes and Augments Their Transfer to Macrophages

(2008) J. Li et al.   INFECTION AND IMMUNITY

Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway

(2008) J. Yuste et al.   INFECTION AND IMMUNITY

Streptococcus pneumoniaeDeficient in Pneumolysin or Autolysin Has Reduced Virulence in Meningitis

(2008) Robert A. Hirst et al.   JOURNAL OF INFECTIOUS DISEASES

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY