Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus

Environmental pH modulation by pathogenic fungi as a strategy to conquer the host

(2017) Slavena Vylkova   PLoS Pathogens

Executive Summary: Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

Executive Summary: Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America

(2016) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

In vivo pH mapping of injured lungs using hyperpolarized [1-13 C]pyruvate

(2016) Nicholas Drachman et al.   MAGNETIC RESONANCE IN MEDICINE

Probe for the measurement of cell surface pH in vivo and ex vivo

(2016) Michael Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

(2016) Fabio Gsaller et al.   PLoS Pathogens

Defining the frontiers between antifungal resistance, tolerance and the concept of persistence

(2015) Eric Delarze et al.   DRUG RESISTANCE UPDATES

International expert opinion on the management of infection caused by azole-resistant Aspergillus fumigatus

(2015) Paul E. Verweij et al.   DRUG RESISTANCE UPDATES

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae

(2015) Catarina Costa et al.   PLoS One

The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

(2014) Margherita Bertuzzi et al.   PLoS Pathogens

Antifungal drug resistance in Candida species

(2014) Giulia Morace et al.   Journal of Global Antimicrobial Resistance

Susceptibility testing in Aspergillus species complex

(2013) C. Lass-Flörl   CLINICAL MICROBIOLOGY AND INFECTION

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus 

(2013) Marcin G. Fraczek et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Modeling, Substrate Docking, and Mutational Analysis Identify Residues Essential for the Function and Specificity of a Eukaryotic Purine-Cytosine NCS1 Transporter

(2012) Emilia Krypotou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus

(2012) Fabio Gsaller et al.   Metallomics

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Loss of Heterozygosity ofFCY2Leading to the Development of Flucytosine Resistance in Candida tropicalis

(2011) Yen-Ning Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

(2011) S. Yasmin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Analysis of Flucytosine Resistance in Candida glabrata

(2010) T. D. Edlind et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

Nonsense and Missense Mutations in FCY2 and FCY1 Genes Are Responsible for Flucytosine Resistance and Flucytosine-Fluconazole Cross-Resistance in Clinical Isolates of Candida lusitaniae

(2009) M. Florent et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The interplay between iron and zinc metabolism in Aspergillus fumigatus

(2009) Sabiha Yasmin et al.   FUNGAL GENETICS AND BIOLOGY

In Vitro Activities at pH 5.0 and pH 7.0 and In Vivo Efficacy of Flucytosine against Aspergillus fumigatus

(2008) P. E. Verweij et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia–forming moulds

(2008)   CLINICAL MICROBIOLOGY AND INFECTION

The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis

(2008) Anna Vlanti et al.   MOLECULAR MICROBIOLOGY