Modeling, Substrate Docking, and Mutational Analysis Identify Residues Essential for the Function and Specificity of a Eukaryotic Purine-Cytosine NCS1 Transporter

Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis

(2012) George S. Mourad et al.   FEBS LETTERS

γ-Tubulin plays a key role in inactivating APC/CCdh1at the G1–S boundary

(2012) Heather Edgerton-Morgan et al.   JOURNAL OF CELL BIOLOGY

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

Antifungal Drug Resistance: Mechanisms, Epidemiology, and Consequences for Treatment

(2011) Michael A. Pfaller   AMERICAN JOURNAL OF MEDICINE

Simulations of the Alternating Access Mechanism of the Sodium Symporter Mhp1

(2011) Joshua L. Adelman et al.   BIOPHYSICAL JOURNAL

Mutational Analysis and Modeling Reveal Functionally Critical Residues in Transmembrane Segments 1 and 3 of the UapA Transporter

(2011) Sotiris Amillis et al.   JOURNAL OF MOLECULAR BIOLOGY

The ubiquitous Nucleobase-Ascorbate Transporter (NAT) family: Lessons from model microbial genetic systems

(2010) George Diallinas et al.   Channels

Dynamic Elements at Both Cytoplasmically and Extracellularly Facing Sides of the UapA Transporter Selectively Control the Accessibility of Substrates to Their Translocation Pathway

(2010) Vasiliki Kosti et al.   JOURNAL OF MOLECULAR BIOLOGY

The alternating access mechanism of transport as observed in the sodium-hydantoin transporter Mhp1

(2010) Simone Weyand et al.   JOURNAL OF SYNCHROTRON RADIATION

Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

(2010) T. Shimamura et al.   SCIENCE

Structure and function of Na+-symporters with inverted repeats

(2009) Jeff Abramson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nucleoside/nucleobase transporters: drug targets of the future?

(2009) Meryem Köse et al.   Future Medicinal Chemistry

Convergent evolution and orphan genes in the Fur4p-like family and characterization of a general nucleoside transporter inAspergillus nidulans

(2009) Zsuzsanna Hamari et al.   MOLECULAR MICROBIOLOGY

Transport-dependent endocytosis and turnover of a uric acid-xanthine permease

(2009) Christos Gournas et al.   MOLECULAR MICROBIOLOGY

Molecular basis of transport and regulation in the Na+/betaine symporter BetP

(2009) Susanne Ressl et al.   NATURE

Unlocking the molecular secrets of sodium-coupled transporters

(2009) Harini Krishnamurthy et al.   NATURE

Structure and Mechanism of an Amino Acid Antiporter

(2009) X. Gao et al.   SCIENCE

Structure and Mechanism of a Na+-Independent Amino Acid Transporter

(2009) P. L. Shaffer et al.   SCIENCE

Specific Interdomain Synergy in the UapA Transporter Determines Its Unique Specificity for Uric Acid among NAT Carriers

(2008) Ioannis Papageorgiou et al.   JOURNAL OF MOLECULAR BIOLOGY

The nucleobase–ascorbate transporter (NAT) family: genomics, evolution, structure–function relationships and physiological role

(2008) Christos Gournas et al.   Molecular BioSystems

The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis

(2008) Anna Vlanti et al.   MOLECULAR MICROBIOLOGY

A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation

(2008) S. K. Singh et al.   SCIENCE

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

(2008) S. Weyand et al.   SCIENCE

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

(2008) S. Faham et al.   SCIENCE