☆ 4.7 Letter

Coffee consumption and gout: a Mendelian randomisation study

ANNALS OF THE RHEUMATIC DISEASES (2018)

期刊

ANNALS OF THE RHEUMATIC DISEASES

卷 77, 期 10, 页码 1544-1546

出版社

BMJ PUBLISHING GROUP

DOI: 10.1136/annrheumdis-2018-213055

关键词

-

类别

Rheumatology

向作者/读者索取更多资源

Protocol

Reagent

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7

评分不足

次要评分

新颖性

-

重要性

-

科学严谨性

-

评价这篇论文

推荐

Article Nutrition & Dietetics

Coffee consumption and cancer risk: a Mendelian randomisation study

Paul Carter, Shuai Yuan, Siddhartha Kar, Mathew Vithayathil, Amy M. Mason, Stephen Burgess, Susanna C. Larsson

Summary: This Mendelian randomisation study investigated the causal associations of coffee consumption with various cancers. The results showed that coffee consumption was associated with an increased risk of oesophageal cancer, but not with the majority of other cancer types. However, coffee consumption was associated with an increased risk of multiple myeloma and a reduced risk of ovarian cancer.

CLINICAL NUTRITION (2022)

添加到收藏夹

Article Rheumatology

Sodium-glucose cotransporter 1 inhibition and gout: Mendelian randomisation study

Sizheng Steven Zhao, Skanda Rajasundaram, Ville Karhunen, Uazman Alam, Dipender Gill

Summary: Genetically proxied SGLT1 inhibition is associated with reduced gout risk and serum urate levels, but not with increased risk of coronary heart disease, stroke, or chronic kidney disease. This suggests that SGLT1 inhibition may be a novel therapeutic option for preventing gout.

SEMINARS IN ARTHRITIS AND RHEUMATISM (2022)

添加到收藏夹

Article Nutrition & Dietetics

Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study

Felix O'Farrell, Xiyun Jiang, Shahad Aljifri, Raha Pazoki

Summary: This study analyzed the relationship between alcohol consumption and various phenotypes, finding causal relationships between alcohol consumption and certain diseases, as well as identifying mediators such as gamma glutamyltransferase and physical inactivity.

NUTRIENTS (2022)

添加到收藏夹

Article Psychiatry

Cigarette smoking, coffee consumption, alcohol intake, and clozapine metabolism: A Mendelian randomization study

Lingsi Zeng, Honggang Lv, Juan Li, Ranran Xue, Xia Liu, Cong Zhou, Hao Yu

Summary: This study revealed correlations between smoking initiation and coffee consumption with reduced blood levels of clozapine and norclozapine, providing guidance for clinicians in adjusting clozapine levels for treated patients.

FRONTIERS IN PSYCHIATRY (2022)

添加到收藏夹

Article Nutrition & Dietetics

Milk consumption and risk of twelve cancers: A large-scale observational and Mendelian randomisation study

Amanda L. Lumsden, Anwar Mulugeta, Elina Hypponen

Summary: This study assessed the potential causal relationships between milk consumption and 12 types of cancer. The results showed a protective role of milk consumption in colorectal cancer, but a higher risk of breast cancer and premenopausal uterine cancer. Further investigation is needed to confirm these findings.

CLINICAL NUTRITION (2023)

添加到收藏夹

Article Endocrinology & Metabolism

Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study

Yangchang Zhang, Jun Fan, Li Chen, Yang Xiong, Tingting Wu, Shisi Shen, Xu Wang, Xuchen Meng, Yanjun Lu, Xun Lei

Summary: The study found that genetically predicted coffee consumption has a causal effect on the risk of overall, knee, and self-reported osteoarthritis, but not on hip osteoarthritis. Further research is needed to elucidate the role of coffee consumption in osteoarthritis prevention.

FRONTIERS IN ENDOCRINOLOGY (2021)

添加到收藏夹

Article Cell Biology

Telomere length and metabolic syndrome traits: A Mendelian randomisation study

Nellie Y. Loh, Raymond Noordam, Constantinos Christodoulides

Summary: Genetically instrumented longer leukocyte telomere length is associated with higher waist-to-hip ratio, raised blood pressure, and increased risk of Metabolic Syndrome.

AGING CELL (2021)

添加到收藏夹

Article Nutrition & Dietetics

Coffee and caffeine consumption and risk of renal cell carcinoma: A Mendelian randomization study

Bing-Hui Li, Si-Yu Yan, Xu-Hui Li, Qiao Huang, Li-Sha Luo, Yun-Yun Wang, Jiao Huang, Ying-Hui Jin, Yong-Bo Wang

Summary: The study using Mendelian randomization did not find a causal relationship between coffee and caffeine consumption and the risk of renal cell carcinoma. Further well-powered studies are needed to confirm the associations.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Article Geriatrics & Gerontology

Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study

Jiahao Zhu, Dan Zhou, Jing Wang, Ye Yang, Dingwan Chen, Fan He, Yingjun Li

Summary: This study used Mendelian randomisation analysis to find a bidirectional causal association between frailty and cardiometabolic diseases such as coronary artery disease, stroke, and type 2 diabetes. Further understanding of this association is crucial for improving care in older adults.

AGE AND AGEING (2022)

添加到收藏夹

Article Genetics & Heredity

Modifiable lifestyle factors and severe COVID-19 risk: a Mendelian randomisation study

Shuai Li, Xinyang Hua

Summary: Genetic analysis suggests that BMI and smoking are causally linked to an increased risk of COVID-19 severe illness, while physical activity may decrease this risk. No significant association was found between alcohol consumption and COVID-19 severe illness.

BMC MEDICAL GENOMICS (2021)

添加到收藏夹

Article Genetics & Heredity

Coffee consumption and periodontitis: a Mendelian Randomization study

Wan-Zhe Liao, Zhi-Yi Zhou, Zi-Kai Lin, Shuo-Jia Xie, Ya-Fang Zheng, Jun-Tao Wang, Jun-Huang Zheng, Hao-Kai Chen, Wu-Shu Chen, Xu-Guang Guo

Summary: This study aimed to uncover the causal relationship between coffee consumption and the susceptibility to periodontitis. The results showed that continuous coffee consumption was associated with an increased risk of periodontitis, while binary coffee consumption did not show a strong causal association.

GENES AND NUTRITION (2023)

添加到收藏夹

Article Rheumatology

Assessing the causal relationships between gout and hypertension: a bidirectional Mendelian randomisation study with coarsened exposures

Benjamin Lai, Huang-Ping Yu, Yu-Jing Chang, Liang-Chin Wang, Che-Kai Chen, Weiya Zhang, Michael Doherty, Shang-Hung Chang, Jun-Te Hsu, Kuang-Hui Yu, Chang-Fu Kuo

Summary: This study found a causal relationship between gout and hypertension, with gout predisposition leading to the development of hypertension. However, there was no causal effect of hypertension predisposition on gout. Adequate management of gout may reduce the risk of developing hypertension.

ARTHRITIS RESEARCH & THERAPY (2022)

添加到收藏夹

Article Medicine, General & Internal

Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study

Yiwen Long, Lanhua Tang, Yangying Zhou, Shushan Zhao, Hong Zhu

Summary: This study suggests a causal association between the gut microbiota and cancer, providing new insights for further research on the mechanisms and clinical implications of microbiota-mediated cancer.

BMC MEDICINE (2023)

添加到收藏夹

Article Medicine, General & Internal

Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study

Vasilios Karageorgiou, Francesco Casanova, Jessica OLoughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden, Jessica Tyrrell

Summary: This study investigates the impact of inflammation and body mass index (BMI) on depression and treatment-resistant depression using genetic information and Mendelian randomisation (MR). The results show a positive association between BMI and depression, particularly in females and younger individuals. BMI has an independent causal effect on treatment-resistant depression, not through inflammation. Understanding the relationship between BMI and depression can help improve clinical treatment.

BMC MEDICINE (2023)

添加到收藏夹

Article Nutrition & Dietetics

Mendelian randomization study of coffee consumption and age at onset of Huntington's disease

Mengmeng Wang, Marilyn C. Cornelis, Zhizhong Zhang, Dandan Liu, Xuegan Lian

Summary: The study suggests a potential causal relationship between high coffee consumption and earlier onset of Huntington's disease, utilizing Mendelian randomization and genetic data.

CLINICAL NUTRITION (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Inverse Association Between Serum 25-Hydroxyvitamin D and Nonalcoholic Fatty Liver Disease

Shuai Yuan, Susanna C. Larsson

Summary: This study conducted a bidirectional Mendelian randomization to explore the association between serum 25-hydroxyvitamin D and NAFLD. It found that increased vitamin D levels may play a role in preventing NAFLD in European populations.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2023)

添加到收藏夹

Article Oncology

Morning chronotype and digestive tract cancers: Mendelian randomization study

Shuai Yuan, Amy M. Mason, Olga E. Titova, Mathew Vithayathil, Siddhartha Kar, Jie Chen, Xue Li, Stephen Burgess, Susanna C. Larsson

Summary: Morning chronotype is associated with a reduced risk of digestive tract cancer, particularly stomach and colorectal cancers. This Mendelian randomization study provides evidence of the association between morning chronotype and digestive tract cancer.

INTERNATIONAL JOURNAL OF CANCER (2023)

添加到收藏夹

Article Nutrition & Dietetics

Plasma phospholipid arachidonic acid in relation to non-alcoholic fatty liver disease: Mendelian randomization study

Jie Chen, Xixian Ruan, Yuhao Sun, Xue Li, Shuai Yuan, Susanna C. Larsson

Summary: This study used Mendelian randomization analysis and found potential causal associations between high levels of plasma phospholipid AA and the risk of NAFLD and cirrhosis, based on data from three different sources.

NUTRITION (2023)

添加到收藏夹

Article Nutrition & Dietetics

Genetically predicted coffee and tea consumption and risk of intracranial aneurysm

Zhizhong Zhang, Mengmeng Wang, Shuai Yuan, Susanna C. C. Larsson, Xinfeng Liu

Summary: Using genetic data, this study found that coffee consumption may increase the risk of intracranial aneurysm (IA) and associated hemorrhage. However, tea consumption was not associated with any type of IA.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2023)

添加到收藏夹

Article Medicine, General & Internal

Urinary phosphate is associated with cardiovascular disease incidence

Carolina Donat-Vargas, Pilar Guallar-Castillon, Jenny Nystrom, Susanna C. Larsson, Maria Kippler, Marie Vahter, Gerd Faxen-Irving, Karl Michaelsson, Alicja Wolk, Peter Stenvinkel, Agneta Akesson

Summary: Elevated phosphate in urine may indicate high intake of inorganic P salts from food additives. Elevated phosphate in plasma is linked to vascular dysfunction and calcification. This study explored the associations between phosphate in urine and plasma, estimated phosphate intake, and incidence of cardiovascular disease (CVD). It found that higher levels of urinary phosphate were associated with CVD and myocardial infarctions. Plasma phosphate showed a weaker association with CVD.

JOURNAL OF INTERNAL MEDICINE (2023)

添加到收藏夹

Article Pediatrics

Perioperative water and electrolyte balance and water homeostasis regulation in children with acute surgery

Daniel N. Roberts, Paula Vallen, Maria Cronhjort, Tobias Alfven, Gabriel Sandblom, Susanna Tonroth-Horsefield, Boye L. Jensen, Per-Arne Lonnqvist, Robert Frithiof, Mattias Carlstrom, Rafael T. Krmar

Summary: This study aimed to assess the post-operative plasma-sodium concentration in children with acute appendicitis and provide a physiological explanation for plasma-sodium levels over time. The findings suggest that the use of moderately hypotonic fluid therapy after correction of extracellular fluid deficit is not necessarily associated with post-operative hyponatremia.

PEDIATRIC RESEARCH (2023)

添加到收藏夹

Article Psychiatry

Depression and 24 gastrointestinal diseases: a Mendelian randomization study

Xixian Ruan, Jie Chen, Yuhao Sun, Yao Zhang, Jianhui Zhao, Xiaoyan Wang, Xue Li, Shuai Yuan, Susanna C. C. Larsson

Summary: The study used Mendelian randomization analysis to explore the association between depression and 24 gastrointestinal diseases. It was found that genetic variations associated with depression were linked to several gastrointestinal diseases, including irritable bowel syndrome, non-alcoholic fatty liver disease, and ulcerative colitis.

TRANSLATIONAL PSYCHIATRY (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Red blood cells from endothelial nitric oxide synthase-deficient mice induce vascular dysfunction involving oxidative stress and endothelial arginase I

Zhengbing Zhuge, Sarah McCann Haworth, Carina Nihlen, Lucas Rannier R. A. Carvalho, Sophia K. Heuser, Andrei L. Kleschyov, Josefine Nasiell, Miriam M. Cortese-Krott, Eddie Weitzberg, Jon O. Lundberg, Mattias Carlstroem

Summary: This study aimed to investigate the effects of a lack of endothelial nitric oxide synthase (eNOS) in red blood cells (RBCs) on vascular endothelial function. Results showed that RBCs lacking eNOS induced endothelial dysfunction and vascular oxidative stress, similar to RBCs from patients with preeclampsia. This suggests that RBC-derived nitric oxide (NO) bioactivity plays a crucial role in protecting the endothelium from oxidative stress.

REDOX BIOLOGY (2023)

添加到收藏夹

Article Hematology

Long-term risk of venous thromboembolism among patients with gastrointestinal non-neoplastic and neoplastic diseases: A prospective cohort study of 484?211 individuals

Shuai Yuan, Yuhao Sun, Jie Chen, Xue Li, Susanna C. Larsson

Summary: This prospective cohort study found that patients with gallbladder and biliary tract cancer, pancreatic cancer, cirrhosis, Crohn's disease, or pancreatitis have a 50% higher risk of developing venous thromboembolism.

AMERICAN JOURNAL OF HEMATOLOGY (2023)

添加到收藏夹

Article Medicine, General & Internal

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization

Benjamin Woolf, Helene T. Cronje, Loukas Zagkos, Stephen Burgess, Dipender Gill, Susanna C. Larsson

Summary: A Mendelian randomization study found a causal association between higher plasma caffeine levels and the risk of neuropsychiatric disorders (anorexia nervosa, bipolar disorder, major depressive disorder, and schizophrenia).

BMC MEDICINE (2023)

添加到收藏夹

Article Sport Sciences

Elite female endurance athletes are at increased risk of atrial fibrillation compared to the general population: a matched cohort study

Nikola Drca, Susanna C. Larsson, David Grannas, Mats Jensen-Urstad

Summary: This study found that female elite endurance athletes are at a higher risk of atrial fibrillation compared to the general population. The findings suggest that participation in endurance sports may influence the risk of atrial fibrillation in women.

BRITISH JOURNAL OF SPORTS MEDICINE (2023)

添加到收藏夹

Article Endocrinology & Metabolism

Birth weight, childhood obesity, adulthood obesity and body composition, and gastrointestinal diseases: a Mendelian randomization study

Shuai Yuan, Xixian Ruan, Yuhao Sun, Tian Fu, Jianhui Zhao, Minzi Deng, Jie Chen, Xue Li, Susanna C. Larsson

Summary: This Mendelian randomization study reveals a causal association between greater adiposity in adulthood (measured as BMI, waist-hip ratio, or visceral adipose tissue) and an increased risk of a broad range of gastrointestinal diseases in the European population.

OBESITY (2023)

添加到收藏夹

Article Nutrition & Dietetics

Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study

Alice Giontella, Roxane de la Harpe, Helene T. Cronje, Loukas Zagkos, Benjamin Woolf, Susanna C. Larsson, Dipender Gill

Summary: Genetically predicted plasma caffeine levels are associated with a decrease in kidney function, while genetically predicted caffeine intake is associated with an improvement in kidney function.

NUTRIENTS (2023)

添加到收藏夹

Article Physiology

Effect of controlled hypotensive hemorrhage on plasma sodium levels in anesthetized pigs: An exploratory study

Rafael T. Krmar, Stephanie Franzen, Leif Karlsson, Helin Strandberg, Susanna Tornroth-Horsefield, Jesper K. Andresen, Boye L. Jensen, Mattias Carlstrom, Robert Frithiof

Summary: Perioperative hyponatremia is a serious electrolyte disorder caused by the non-osmotic release of arginine vasopressin and is associated with various types of surgery. By using a controlled hypotensive hemorrhage pig model, the effect of bleeding on plasma sodium was investigated. The results showed that all pigs developed hyponatremia after bleeding and were unable to excrete net-free water.

PHYSIOLOGICAL REPORTS (2023)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Mendelian randomization for cardiovascular diseases: principles and applications

Susanna C. Larsson, Adam S. Butterworth, Stephen Burgess

Summary: Mendelian randomization utilizes genetic variation as a natural experiment to improve causal inferences from observational data. It can determine whether a putative risk factor likely has a causal effect on the disease.

EUROPEAN HEART JOURNAL (2023)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.