The role of toll-like receptors in B-cell development and immunopathogenesis of common variable immunodeficiency

Toll like receptors: a new hope on the horizon to treat multiple sclerosis

(2014) Maziar Gooshe et al.   Expert Review of Clinical Immunology

Long-term evaluation of a historical cohort of Iranian common variable immunodeficiency patients

(2014) Asghar Aghamohammadi et al.   Expert Review of Clinical Immunology

A New Era of Targeting the Ancient Gatekeepers of the Immune System: Toll-Like Agonists in the Treatment of Allergic Rhinitis and Asthma

(2014) Zahra Aryan et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

A hypomorphic recombination-activating gene 1 ( RAG1 ) mutation resulting in a phenotype resembling common variable immunodeficiency

(2014) Hassan Abolhassani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells

(2014) I. Bekeredjian-Ding et al.   JOURNAL OF IMMUNOLOGY

The Agonists of TLR4 and 9 Are Sufficient to Activate Memory B Cells to Differentiate into Plasma Cells In Vitro but Not In Vivo

(2014) K. Richard et al.   JOURNAL OF IMMUNOLOGY

CpG Oligonucleotides Enhance Proliferative and Effector Responses of B Cells in HIV-Infected Individuals

(2014) A. Malaspina et al.   JOURNAL OF IMMUNOLOGY

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Viral Double-Stranded RNA Triggers Ig Class Switching by Activating Upper Respiratory Mucosa B Cells through an Innate TLR3 Pathway Involving BAFF

(2014) W. Xu et al.   JOURNAL OF IMMUNOLOGY

TLR Agonists Promote Marginal Zone B Cell Activation and Facilitate T-Dependent IgM Responses

(2014) A. V. Rubtsov et al.   JOURNAL OF IMMUNOLOGY

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9

(2013) E. Taraldsrud et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-like receptors in lymphoid malignancies: Double-edged sword

(2013) Sara Harsini et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Retinoic Acid Improves Defective TLR9/RP105-Induced Immune Responses in Common Variable Immunodeficiency-Derived B Cells

(2013) R. L. Indrevaer et al.   JOURNAL OF IMMUNOLOGY

B Cell-Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection

(2013) J. M. Clingan et al.   JOURNAL OF IMMUNOLOGY

Toll like receptor (TLR)-induced differential expression of microRNAs (MiRs) and immune response against infection: A systematic review

(2013) Seyed Hossein Aalaei-andabili et al.   JOURNAL OF INFECTION

Toll-Like Receptor Polymorphisms, Inflammatory and Infectious Diseases, Allergies, and Cancer

(2013) Andrei E. Medvedev   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Primary immunodeficiencies of pattern recognition receptors

(2013) M. G. Netea et al.   JOURNAL OF INTERNAL MEDICINE

Toll-like Receptor 7 Is Required for Effective Adaptive Immune Responses that Prevent Persistent Virus Infection

(2012) Kevin B. Walsh et al.   Cell Host & Microbe

The many faces of the clinical picture of common variable immune deficiency

(2012) Elena S. Resnick et al.   Current Opinion in Allergy and Clinical Immunology

Genetic variation in Toll-like receptors and disease susceptibility

(2012) Mihai G Netea et al.   NATURE IMMUNOLOGY

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

TLR-Mediated B Cell Defects and IFN-α in Common Variable Immunodeficiency

(2011) Joyce E. Yu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

(2011) Melissa Swiecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting of Toll-like receptors: a decade of progress in combating infectious diseases

(2011) Mona Hedayat et al.   LANCET INFECTIOUS DISEASES

Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response

(2011) Edward P. Browne   PLoS Pathogens

Modulation of B cell responses by Toll-like receptors

(2010) Jayaum Booth et al.   CELL AND TISSUE RESEARCH

Defective B cell response to TLR9 ligand (CpG-ODN), Streptococcus pneumoniae and Haemophilus influenzae extracts in common variable immunodeficiency patients

(2010) Danilo Escobar et al.   CELLULAR IMMUNOLOGY

Alterations in interleukin secretion (IL-2 and IL-4) by CD4 and CD4 CD45RO cells from common variable immunodeficiency (CVI) patients

(2010) J. M. FERRER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Defects in proliferative responses of T cells from patients with common variable immunodeficiency on direct activation of protein kinase C

(2010) M. E. NORTH et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

B-Cell and T-Cell Phenotypes in CVID Patients Correlate with the Clinical Phenotype of the Disease

(2010) Gaël Mouillot et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

(2010) Menno C. van Zelm et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

(2010) Capucine Picard et al.   MEDICINE

Differential regulation of TLR4 expression in human B cells and monocytes

(2010) Lisa M. Ganley-Leal et al.   MOLECULAR IMMUNOLOGY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Regression of systemic lupus erythematosus after development of an acquired Toll-like receptor signaling defect and antibody deficiency

(2009) Marcella Visentini et al.   ARTHRITIS AND RHEUMATISM

Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency

(2009) S. Borte et al.   BLOOD

Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production

(2009) Marcus Dorner et al.   IMMUNOLOGY

Toll-like receptors - sentries in the B-cell response

(2009) Isabelle Bekeredjian-Ding et al.   IMMUNOLOGY

Primary immunodeficiencies: 2009 update

(2009) Luigi D. Notarangelo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Toll-like receptor 7 and 9 defects in common variable immunodeficiency

(2009) Joyce E. Yu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD20 deficiency in humans results in impaired T cell–independent antibody responses

(2009) Taco W. Kuijpers et al.   JOURNAL OF CLINICAL INVESTIGATION

Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells

(2009) I. Douagi et al.   JOURNAL OF IMMUNOLOGY

IFN-α amplifies human naïve B cell TLR-9-mediated activation and Ig production

(2009) L. Giordani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of phosphoinositide 3-kinase p110δ in TLR4- and TLR9-mediated B cell cytokine production and differentiation

(2009) Nyla Dil et al.   MOLECULAR IMMUNOLOGY

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS

B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans

(2009) K. Warnatz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Influx and Death of Plasmacytoid Dendritic Cells in Lymph Nodes Mediate Depletion in Acute Simian Immunodeficiency Virus Infection

(2009) Kevin N. Brown et al.   PLoS Pathogens

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer

(2008) Juan M. Zapata et al.   BLOOD

Toll-like receptors: lessons to learn from normal and malignant human B cells

(2008) D. Chiron et al.   BLOOD

Common variable immunodeficiency disorders: division into distinct clinical phenotypes

(2008) H. Chapel et al.   BLOOD

Comparison of human B cell activation by TLR7 and TLR9 agonists

(2008) John A Hanten et al.   BMC IMMUNOLOGY

Memory B cells in common variable immunodeficiency: Clinical associations and sex differences

(2008) Silvia Sánchez-Ramón et al.   CLINICAL IMMUNOLOGY

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells

(2008) Bo Wei et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

Identification of two subpopulations of purified human blood B cells, CD27− CD23+and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6

(2008) Fabrice Cognasse et al.   IMMUNOLOGY

Toll-like receptor 7–induced naive human B-cell differentiation and immunoglobulin production

(2008) Mark C. Glaum et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells

(2008) Koon-Guan Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revisiting human primary immunodeficiencies

(2008) Jean-Laurent Casanova et al.   JOURNAL OF INTERNAL MEDICINE