标题
Developing models for cachexia and their implications in drug discovery
作者
关键词
-
出版物
Expert Opinion on Drug Discovery
Volume 10, Issue 7, Pages 743-752
出版商
Informa Healthcare
发表日期
2015-04-30
DOI
10.1517/17460441.2015.1041914
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neuroprotective agents target molecular mechanisms of disease in ALS
- (2015) Yongjin Zhu et al. DRUG DISCOVERY TODAY
- Muscle wasting in disease: molecular mechanisms and promising therapies
- (2015) Shenhav Cohen et al. NATURE REVIEWS DRUG DISCOVERY
- Systemic inflammation promotes lung metastasis via E-selectin upregulation in mouse breast cancer model
- (2014) Man Jiang et al. CANCER BIOLOGY & THERAPY
- A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia
- (2014) Michele Petruzzelli et al. Cell Metabolism
- Extracellular Superoxide Dismutase Ameliorates Skeletal Muscle Abnormalities, Cachexia, and Exercise Intolerance in Mice with Congestive Heart Failure
- (2014) Mitsuharu Okutsu et al. Circulation-Heart Failure
- Novel investigational biologics for the treatment of cancer cachexia
- (2014) Joseph D Ma et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Animal models of chronic obstructive pulmonary disease
- (2014) Michael Fricker et al. Expert Opinion on Drug Discovery
- HIF Transcription Factors, Inflammation, and Immunity
- (2014) Asis Palazon et al. IMMUNITY
- Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy
- (2014) Michael C. Dyle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quercetin Supplementation Attenuates the Progression of Cancer Cachexia in ApcMin/+Mice
- (2014) Kandy T. Velázquez et al. JOURNAL OF NUTRITION
- Cardiovascular Function and Predictors of Exercise Capacity in Patients With Colorectal Cancer
- (2014) Larissa Cramer et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
- (2014) Serkan Kir et al. NATURE
- Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
- (2014) H.-Q. Jiang et al. NEUROSCIENCE
- Catabolic Signaling and Muscle Wasting After Acute Ischemic Stroke in Mice
- (2014) Jochen Springer et al. STROKE
- Abstracts of the 7th Cachexia Conference, Kobe/Osaka, Japan, December 9-11, 2013 (Part 2)
- (2014) Journal of Cachexia Sarcopenia and Muscle
- Prevalence, incidence and clinical impact of cachexia: facts and numbers-update 2014
- (2014) Stephan von Haehling et al. Journal of Cachexia Sarcopenia and Muscle
- Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK
- (2013) James P. White et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line
- (2013) Kiyoshi Terawaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours
- (2013) D W Bowles et al. BRITISH JOURNAL OF CANCER
- Guide to the Assessment of Physical Activity: Clinical and Research Applications
- (2013) Scott J. Strath et al. CIRCULATION
- Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia
- (2013) Daniel J. Ham et al. CLINICAL NUTRITION
- Prevention of liver cancer cachexia-induced cardiac wasting and heart failure
- (2013) Jochen Springer et al. EUROPEAN HEART JOURNAL
- TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy
- (2013) Anna Baumgarten et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Tandospirone reduces wasting and improves cardiac function in experimental cancer cachexia
- (2013) Yulia Elkina et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Simvastatin reduces wasting and improves cardiac function as well as outcome in experimental cancer cachexia
- (2013) Sandra Palus et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The xanthine oxidase inhibitor oxypurinol reduces cancer cachexia-induced cardiomyopathy
- (2013) Jochen Springer et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies
- (2013) Erin Schenk et al. INVESTIGATIONAL NEW DRUGS
- The role of interleukin-6 in the evolution of ovarian cancer: clinical and prognostic implications—a review
- (2013) Antonio Macciò et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Survival Benefit With Radium-223 Dichloride in a Mouse Model of Breast Cancer Bone Metastasis
- (2013) Mari I. Suominen et al. JNCI-Journal of the National Cancer Institute
- Inhibitory Effects of Isoflavones on Tumor Growth and Cachexia in Newly Established Cachectic Mouse Models Carrying Human Stomach Cancers
- (2013) Kazuyoshi Yanagihara et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- The anabolic catabolic transforming agent (ACTA) espindolol increases muscle mass and decreases fat mass in old rats
- (2013) Mareike S. Pötsch et al. Journal of Cachexia Sarcopenia and Muscle
- Cachexia as a major public health problem: frequent, costly, and deadly
- (2013) Jerneja Farkas et al. Journal of Cachexia Sarcopenia and Muscle
- Characterization of the male ApcMin/+ mouse as a hypogonadism model related to cancer cachexia
- (2013) J. P. White et al. Biology Open
- Gut barrier dysfunction and microbial translocation in cancer cachexia
- (2013) Gerald L. Klein et al. Current Opinion in Supportive and Palliative Care
- “Iron-saturated” bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice
- (2012) Xueying Sun et al. BMC CANCER
- Inflammation and ovarian cancer
- (2012) Antonio Macciò et al. CYTOKINE
- Angiotensin II Reduces Food Intake by Altering Orexigenic Neuropeptide Expression in the Mouse Hypothalamus
- (2012) Tadashi Yoshida et al. ENDOCRINOLOGY
- Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia
- (2012) Jochen Springer et al. INTERNATIONAL JOURNAL OF CANCER
- Mitochondria as a Therapeutic Target in Heart Failure
- (2012) Marina Bayeva et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ghrelin improves body weight loss and skeletal muscle catabolism associated with angiotensin II-induced cachexia in mice
- (2012) Masako Sugiyama et al. REGULATORY PEPTIDES
- Cancer cachexia: impact, mechanisms and emerging treatments
- (2012) Vanessa C. Vaughan et al. Journal of Cachexia Sarcopenia and Muscle
- Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia
- (2012) Felipe E. Pedroso et al. Journal of Cachexia Sarcopenia and Muscle
- PGC-1α Promotes Nitric Oxide Antioxidant Defenses and Inhibits FOXO Signaling Against Cardiac Cachexia in Mice
- (2011) Tuoyu Geng et al. AMERICAN JOURNAL OF PATHOLOGY
- Angiotensin II, Oxidative Stress and Skeletal Muscle Wasting
- (2011) Sergiy Sukhanov et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor
- (2011) Kyeong Lee et al. ARCHIVES OF PHARMACAL RESEARCH
- Gut barrier dysfunction in the ApcMin/+ mouse model of colon cancer cachexia
- (2011) Melissa J. Puppa et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
- (2011) F. Robert et al. CANCER RESEARCH
- mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass
- (2011) Steven D. Kunkel et al. Cell Metabolism
- Analysis of liver metabolism in a rat model of heart failure
- (2011) Takao Kato et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Definition and classification of cancer cachexia: an international consensus
- (2011) Kenneth Fearon et al. LANCET ONCOLOGY
- Cancer Cachexia and Fat–Muscle Physiology
- (2011) Kenneth C.H. Fearon NEW ENGLAND JOURNAL OF MEDICINE
- Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia
- (2011) S. K. Das et al. SCIENCE
- Ursodeoxycholic acid treatment in a rat model of cancer cachexia
- (2011) Anika Tschirner et al. Journal of Cachexia Sarcopenia and Muscle
- Potentiation of ghrelin signaling attenuates cancer anorexia–cachexia and prolongs survival
- (2011) N Fujitsuka et al. Translational Psychiatry
- Changes in the renin angiotensin system during the development of colorectal cancer liver metastases
- (2010) Jaclyn H Neo et al. BMC CANCER
- Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner
- (2010) P. F. Cosper et al. CANCER RESEARCH
- Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
- (2010) Xiaolan Zhou et al. CELL
- Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure
- (2010) Takao Kato et al. Circulation-Heart Failure
- Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”
- (2010) M. Muscaritoli et al. CLINICAL NUTRITION
- Activity level, apoptosis, and development of cachexia in ApcMin/+ mice
- (2010) Kristen A. Baltgalvis et al. JOURNAL OF APPLIED PHYSIOLOGY
- Myocardial dysfunction in an animal model of cancer cachexia
- (2010) Hui Xu et al. LIFE SCIENCES
- Animal models of the cancer anorexia–cachexia syndrome
- (2010) Nabila Bennani-Baiti et al. SUPPORTIVE CARE IN CANCER
- Cachexia as a major underestimated and unmet medical need: facts and numbers
- (2010) Stephan von Haehling et al. Journal of Cachexia Sarcopenia and Muscle
- Lenalidomide (Revlimid®) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis
- (2009) Arie Neymotin et al. EXPERIMENTAL NEUROLOGY
- Animal models of anorexia and cachexia
- (2009) Mark D DeBoer Expert Opinion on Drug Discovery
- Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis
- (2009) Lana Kupershmidt et al. FASEB JOURNAL
- Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice
- (2008) Steven J. Del Signore et al. Amyotrophic Lateral Sclerosis
- Cachexia: A new definition
- (2008) William J. Evans et al. CLINICAL NUTRITION
- Cachexia: prevalence and impact in medicine
- (2008) Benjamin HL Tan et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Rikkunshito, an Herbal Medicine, Suppresses Cisplatin-Induced Anorexia in Rats Via 5-HT2 Receptor Antagonism
- (2008) Hiroshi Takeda et al. GASTROENTEROLOGY
- Cardiac Plasticity
- (2008) Joseph A. Hill et al. NEW ENGLAND JOURNAL OF MEDICINE
- Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc Min/+ mouse
- (2008) Kristen A. Baltgalvis et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Cardiac cachexia: A systematic overview
- (2008) Stephan von Haehling et al. PHARMACOLOGY & THERAPEUTICS
- Weight Loss After Stroke
- (2008) Ann-Cathrin Jönsson et al. STROKE
- Interleukin-6 and cachexia in ApcMin/+ mice
- (2007) Kristen A. Baltgalvis et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
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