MALDI imaging facilitates new topical drug development process by determining quantitative skin distribution profiles

Inhibition of Sebum Production with the Acetyl Coenzyme A Carboxylase Inhibitor Olumacostat Glasaretil

(2017) David W. Hunt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Fatty acids penetration into human skin ex vivo: A TOF-SIMS analysis approach

(2017) Vytis Čižinauskas et al.   Biointerphases

MALDI-MS of drugs: Profiling, imaging, and steps towards quantitative analysis

(2016) Sarah D. Turker et al.   APPLIED SPECTROSCOPY REVIEWS

New Drugs and Treatment Targets in Psoriasis

(2015) K Kofoed et al.   ACTA DERMATO-VENEREOLOGICA

Roflumilast: A Review in COPD

(2015) Karly P. Garnock-Jones   DRUGS

Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial

(2015) Hervé Bachelez et al.   LANCET

Imaging of Distribution of Topically Applied Drug Molecules in Mouse Skin by Combination of Time-of-Flight Secondary Ion Mass Spectrometry and Scanning Electron Microscopy

(2014) Peter Sjövall et al.   ANALYTICAL CHEMISTRY

Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis

(2014) Jakob Felding et al.   JOURNAL OF MEDICINAL CHEMISTRY

Distribution and Visualisation of Chlorhexidine Within the Skin Using ToF-SIMS: A Potential Platform for the Design of More Efficacious Skin Antiseptic Formulations

(2013) Amy M. Judd et al.   PHARMACEUTICAL RESEARCH

Quantitative imaging of a therapeutic peptide in biological tissue sections by MALDI MS

(2013) Nozomi Takai et al.   Bioanalysis

Penetration enhancers

(2012) Adrian C. Williams et al.   ADVANCED DRUG DELIVERY REVIEWS

Quantitative MALDI Tandem Mass Spectrometric Imaging of Cocaine from Brain Tissue with a Deuterated Internal Standard

(2012) David A. Pirman et al.   ANALYTICAL CHEMISTRY

Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor

(2012) Gregory Hamm et al.   Journal of Proteomics

Ruxolitinib

(2012) Ruben A. Mesa et al.   NATURE REVIEWS DRUG DISCOVERY

Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:in vitroevaluation of drug permeation by infrared spectroscopy

(2012) Simona Mura et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Imaging the Distribution of Sodium Dodecyl Sulfate in Skin by Confocal Raman and Infrared Microspectroscopy

(2012) G. Mao et al.   PHARMACEUTICAL RESEARCH

Effect of Vehicles on the Maximum Transepidermal Flux of Similar Size Phenolic Compounds

(2012) Qian Zhang et al.   PHARMACEUTICAL RESEARCH

Quantitation by MS imaging: needs and challenges in pharmaceuticals

(2012) Jonathan Stauber   Bioanalysis

MALDI-MS imaging of lipids in ex vivo human skin

(2011) Philippa J. Hart et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improved sample preparation for MALDI–MSI of endogenous compounds in skin tissue sections and mapping of exogenous active compounds subsequent to ex-vivo skin penetration

(2011) Bernd Enthaler et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin

(2011) Qian Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Malignancy concerns of topical calcineurin inhibitors for atopic dermatitis: facts and controversies

(2009) Diamant Thaçi et al.   CLINICS IN DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2009) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2008) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

(2008) Christian W. Freudiger et al.   SCIENCE