Nanocarrier-based antioxidant therapy: promise or delusion?

Coping with oxidative stress

(2015) U. Krengel et al.   SCIENCE

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

(2015) Claire E. Schaar et al.   PLoS Genetics

Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation

(2014) Elizabeth D. Hood et al.   BIOMATERIALS

Improvement of quercetin protective effect against oxidative stress skin damages by incorporation in nanovesicles

(2014) Maria Letizia Manca et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis

(2014) Ernesto Miquel et al.   FREE RADICAL BIOLOGY AND MEDICINE

The mitochondrial-targeted antioxidant MitoQ ameliorates metabolic syndrome features in obesogenic diet-fed rats better than Apocynin or Allopurinol

(2014) Christine Feillet-Coudray et al.   FREE RADICAL RESEARCH

Nanocarrier: A potential tool for future antioxidant therapy

(2014) L. Du et al.   FREE RADICAL RESEARCH

Role of Metabolic H2O2Generation

(2014) Helmut Sies   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol-Loaded Nanoparticles Reduce Oxidative Stress Induced by Radiation or Amyloid- in Transgenic Caenorhabditis elegans

(2014) Haitao Yin et al.   Journal of Biomedical Nanotechnology

Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

(2014) Rachel A. Gioscia-Ryan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?

(2014) Torbjörn Persson et al.   Oxidative Medicine and Cellular Longevity

Superoxide Dismutase Enzymosomes: Carrier Capacity Optimization, in Vivo Behaviour and Therapeutic Activity

(2014) M. Luísa Corvo et al.   PHARMACEUTICAL RESEARCH

Reactive Oxygen Species-Scavenging Nanomedicines for the Treatment of Oxidative Stress Injuries

(2014) Toru Yoshitomi et al.   Advanced Healthcare Materials

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

(2013) Amarjargal Dashdorj et al.   BMC Medicine

Superoxide dismutase-loaded biodegradable nanoparticles targeted with a follicle-stimulating hormone peptide protect Sertoli cells from oxidative stress

(2013) Devon C. Snow-Lisy et al.   FERTILITY AND STERILITY

Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

(2013) Rita Perfeito et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of transcription-independent damage signals in the initiation of epithelial wound healing

(2013) João V. Cordeiro et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

(2012) Tiago R. Figueira et al.   ANTIOXIDANTS & REDOX SIGNALING

The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease

(2012) María E. Solesio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease

(2011) Patrizia Mecocci et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Strategies to Target Mitochondria and Oxidative Stress by Antioxidants: Key Points and Perspectives

(2011) Marvin Edeas   PHARMACEUTICAL RESEARCH

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Why Have Antioxidants Failed in Clinical Trials?

(2008) Steven R. Steinhubl   AMERICAN JOURNAL OF CARDIOLOGY

Should Supplemental Antioxidant Administration Be Avoided During Chemotherapy and Radiation Therapy?

(2008) B. D. Lawenda et al.   JNCI-Journal of the National Cancer Institute