Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway

Autophagy and inflammation: A special review issue

(2018) Vojo Deretic et al.   Autophagy

Autophagy gene FIP200 in neural progenitors non–cell autonomously controls differentiation by regulating microglia

(2017) Chenran Wang et al.   JOURNAL OF CELL BIOLOGY

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

(2017) Yingli He et al.   JOURNAL OF CELL BIOLOGY

Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer's disease: the emerging role for microglia?

(2017) Sami Piirainen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Autophagy activation attenuates angiotensin II-induced cardiac fibrosis

(2016) Shenglan Liu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

(2016) Juan Carlos Corona et al.   FREE RADICAL BIOLOGY AND MEDICINE

ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis

(2016) Zili Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

The antidepressant-like effects of pioglitazone in a chronic mild stress mouse model are associated with PPARγ-mediated alteration of microglial activation phenotypes

(2016) Qiuying Zhao et al.   Journal of Neuroinflammation

1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype

(2016) Ioanna Plastira et al.   Journal of Neuroinflammation

Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors

(2016) M Guo et al.   MOLECULAR PSYCHIATRY

The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects

(2016) Philip Hallenborg et al.   PROGRESS IN LIPID RESEARCH

Neuroimmune Interface in the Comorbidity between Alcohol Use Disorder and Major Depression

(2016) Sudan Prasad Neupane   Frontiers in Immunology

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling

(2015) Ruiting Lin et al.   NATURE CELL BIOLOGY

Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia

(2015) Lijuan Han et al.   STROKE

The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control

(2015) Sravanth K. Hindupur et al.   Cold Spring Harbor Perspectives in Biology

The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

(2014) Chul-Su Yang et al.   Autophagy

Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms

(2014) F. Rohan Walker et al.   BRAIN BEHAVIOR AND IMMUNITY

Sublime Microglia: Expanding Roles for the Guardians of the CNS

(2014) Michael W. Salter et al.   CELL

Vancomycin blocks autophagy and induces interleukin-1β release in macrophages

(2014) Young Eun Ha et al.   JOURNAL OF ANTIBIOTICS

Microglial priming in neurodegenerative disease

(2014) V. Hugh Perry et al.   Nature Reviews Neurology

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization

(2012) Hildegard I.D. Mack et al.   Autophagy

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

(2012) S. Mandrekar-Colucci et al.   JOURNAL OF NEUROSCIENCE

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation

(2011) Libin Shang et al.   Autophagy

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

A pilot test of pioglitazone as an add-on in patients with relapsing remitting multiple sclerosis

(2009) Claudia C. Kaiser et al.   JOURNAL OF NEUROIMMUNOLOGY