Virion-Like Membrane-Breaking Nanoparticles with Tumor-Activated Cell-and-Tissue Dual-Penetration Conquer Impermeable Cancer

Tumor-Penetrating Nanosystem Strongly Suppresses Breast Tumor Growth

(2017) Shweta Sharma et al.   NANO LETTERS

Tumor-Specific Multiple Stimuli-Activated Dendrimeric Nanoassemblies with Metabolic Blockade Surmount Chemotherapy Resistance

(2016) Yachao Li et al.   ACS Nano

Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities

(2016) Jessie L.-S. Au et al.   ADVANCED DRUG DELIVERY REVIEWS

Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain

(2016) Jinyoung Kang et al.   ADVANCED MATERIALS

In vitro and ex vivo strategies for intracellular delivery

(2016) Martin P. Stewart et al.   NATURE

Tuning Endothelial Permeability with Functionalized Nanodiamonds

(2015) Magdiel I. Setyawati et al.   ACS Nano

Virus-Inspired Mimics Based on Dendritic Lipopeptides for Efficient Tumor-Specific Infection and Systemic Drug Delivery

(2015) Zhijun Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Peptide Assembly Integration of Fibroblast-Targeting and Cell-Penetration Features for Enhanced Antitumor Drug Delivery

(2015) Tianjiao Ji et al.   ADVANCED MATERIALS

A Peptide-Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy

(2015) Ya Liu et al.   ADVANCED MATERIALS

Bioinspired Therapeutic Dendrimers as Efficient Peptide Drugs Based on Supramolecular Interactions for Tumor Inhibition

(2015) Xiao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

(2015) Chun-Yang Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing Accumulation and Penetration of HPMA Copolymer–Doxorubicin Conjugates in 2D and 3D Prostate Cancer Cells via iRGD Conjugation with an MMP-2 Cleavable Spacer

(2015) Zheng-Hong Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Liposome-Based Engineering of Cells To Package Hydrophobic Compounds in Membrane Vesicles for Tumor Penetration

(2015) Junsung Lee et al.   NANO LETTERS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Bio-Inspired Supramolecular Hybrid Dendrimers Self-Assembled from Low-Generation Peptide Dendrons for Highly Efficient Gene Delivery and Biological Tracking

(2014) Xianghui Xu et al.   ACS Nano

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

(2014) Limin Pan et al.   ADVANCED MATERIALS

Peptide-Tunable Drug Cytotoxicity via One-Step Assembled Polymer Nanoparticles

(2013) Kang Liang et al.   ADVANCED MATERIALS

Caged Pt Nanoclusters Exhibiting Corrodibility to Exert Tumor-Inside Activation for Anticancer Chemotherapeutics

(2013) Chih-Te Chien et al.   ADVANCED MATERIALS

Development of drug loaded nanoparticles for tumor targeting. Part 2: Enhancement of tumor penetration through receptor mediated transcytosis in 3D tumor models

(2013) Mohammad H. El-Dakdouki et al.   Nanoscale

The ins and outs of hepatitis C virus entry and assembly

(2013) Brett D. Lindenbach et al.   NATURE REVIEWS MICROBIOLOGY

Dendrimers in biomedical applications—reflections on the field

(2012) Sönke Svenson et al.   ADVANCED DRUG DELIVERY REVIEWS

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles

(2012) Erkki Ruoslahti   ADVANCED MATERIALS

Cooperative Hierarchical Self-Assembly of Peptide Dendrimers and Linear Polypeptides into Nanoarchitectures Mimicking Viral Capsids

(2012) Xianghui Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery

(2012) Erlei Jin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shape Matters: Intravital Microscopy Reveals Surprising Geometrical Dependence for Nanoparticles in Tumor Models of Extravasation

(2012) Bryan Ronain Smith et al.   NANO LETTERS

Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses

(2011) Kanjiro Miyata et al.   CHEMICAL SOCIETY REVIEWS

Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

(2010) K. N. Sugahara et al.   SCIENCE

Dynamic Visualization of RGD-Quantum Dot Binding to Tumor Neovasculature and Extravasation in Multiple Living Mouse Models Using Intravital Microscopy

(2010) Bryan Ronain Smith et al.   Small

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent

(2009) Lihong Liu et al.   Nature Nanotechnology

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV TAT Forms Pores in Membranes by Inducing Saddle-Splay Curvature: Potential Role of Bidentate Hydrogen Bonding

(2008) Abhijit Mishra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY

The design of guanidinium-rich transporters and their internalization mechanisms

(2007) Paul A. Wender et al.   ADVANCED DRUG DELIVERY REVIEWS