Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease
出版年份 2017 全文链接
标题
Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease
作者
关键词
-
出版物
Frontiers in Oncology
Volume 7, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-07-10
DOI
10.3389/fonc.2017.00139
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization
- (2017) Linlin Gu et al. FASEB JOURNAL
- Inhibition of mitochondrial calcium uptake 1 in Drosophila neurons
- (2017) P.G. M’Angale et al. GENETICS AND MOLECULAR RESEARCH
- Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
- (2017) Zhiwei Dong et al. MOLECULAR CELL
- Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter
- (2017) Chan Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteolytic control of the mitochondrial calcium uniporter complex
- (2017) Chen-Wei Tsai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca 2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
- (2017) Melanie Paillard et al. Cell Reports
- The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation
- (2017) Varda Shoshan-Barmatz et al. Frontiers in Oncology
- Analysis of the structure and function of EMRE in a yeast expression system
- (2016) Takenori Yamamoto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The VDAC channel: Molecular basis for selectivity
- (2016) Marco Colombini BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- VDAC2-specific cellular functions and the underlying structure
- (2016) Shamim Naghdi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α
- (2016) Anna Tosatto et al. EMBO Molecular Medicine
- The m -AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria
- (2016) Tim König et al. MOLECULAR CELL
- A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca 2+ Uptake Machinery of Skeletal Muscle
- (2016) Denis Vecellio Reane et al. MOLECULAR CELL
- High-throughput discovery of novel developmental phenotypes
- (2016) Mary E. Dickinson et al. NATURE
- Architecture of the mitochondrial calcium uniporter
- (2016) Kirill Oxenoid et al. NATURE
- Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition
- (2016) Dipayan Chaudhuri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca2+ uptake in immortalized cells
- (2016) Corina T. Madreiter-Sokolowski et al. Nature Communications
- MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration
- (2016) Anil Noronha Antony et al. Nature Communications
- MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload
- (2016) Julia C. Liu et al. Cell Reports
- MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics
- (2016) Dhanendra Tomar et al. Cell Reports
- EMRE Is a Matrix Ca 2+ Sensor that Governs Gatekeeping of the Mitochondrial Ca 2+ Uniporter
- (2016) Horia Vais et al. Cell Reports
- Inhibiting the Mitochondrial Calcium Uniporter during Development Impairs Memory in Adult Drosophila
- (2016) Ilaria Drago et al. Cell Reports
- Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex
- (2016) Ming-Feng Tsai et al. eLife
- VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology
- (2016) Simona Reina et al. Frontiers in Oncology
- Loss of Heterozygosity at the Calcium Regulation Gene Locus on Chromosome 10q in Human Pancreatic Cancer
- (2015) Jin Long et al. Asian Pacific Journal of Cancer Prevention
- Mitochondrial Ca2+ uniporter is critical for store-operated Ca2+ entry-dependent breast cancer cell migration
- (2015) Shihao Tang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- CCDC90A (MCUR1) Is a Cytochrome c Oxidase Assembly Factor and Not a Regulator of the Mitochondrial Calcium Uniporter
- (2015) Vincent Paupe et al. Cell Metabolism
- MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter
- (2015) Horia Vais et al. Cell Metabolism
- The Ca2+-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca2+ Uptake
- (2015) Carmelina Petrungaro et al. Cell Metabolism
- Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter
- (2015) Y. Lee et al. EMBO REPORTS
- MiR-25 Protects Cardiomyocytes against Oxidative Damage by Targeting the Mitochondrial Calcium Uniporter
- (2015) Lei Pan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter
- (2015) Kira M. Holmström et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
- (2015) Tyler P. Rasmussen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
- (2015) Santhanam Shanmughapriya et al. Science Signaling
- The mitochondrial uniporter controls fight or flight heart rate increases
- (2015) Yuejin Wu et al. Nature Communications
- Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
- (2015) Alessandro Rimessi et al. Nature Communications
- Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC
- (2015) Xuan Zhou et al. Oncotarget
- The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo
- (2015) Cristina Mammucari et al. Cell Reports
- The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition
- (2015) Timothy S. Luongo et al. Cell Reports
- The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart
- (2015) Jennifer Q. Kwong et al. Cell Reports
- Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
- (2015) Santhanam Shanmughapriya et al. Science Signaling
- Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells
- (2015) Mi Jin Yoon et al. Oncotarget
- Adrenergic Signaling Regulates Mitochondrial Ca2+ Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca2+ Uniporter
- (2014) Jin O-Uchi et al. ANTIOXIDANTS & REDOX SIGNALING
- Unresolved questions from the analysis of mice lacking MCU expression
- (2014) Elizabeth Murphy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Voltage-dependent anion channels: the wizard of the mitochondrial outer membrane
- (2014) Barbara Mertins et al. BIOLOGICAL CHEMISTRY
- C. elegans Epidermal Wounding Induces a Mitochondrial ROS Burst that Promotes Wound Repair
- (2014) Suhong Xu et al. DEVELOPMENTAL CELL
- Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake
- (2014) L. Wang et al. EMBO JOURNAL
- MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter
- (2014) K. J. Kamer et al. EMBO REPORTS
- Components of cancer metabolism and therapeutic interventions
- (2014) John Singleterry et al. MITOCHONDRION
- MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity
- (2014) Maria Patron et al. MOLECULAR CELL
- Joiner et al. reply
- (2014) Mei-ling A. Joiner et al. NATURE
- Mitochondrial Ca2+ uniporter and CaMKII in heart
- (2014) Francesca Fieni et al. NATURE
- Mitochondrial Calcium Uniporter Activity Is Dispensable for MDA-MB-231 Breast Carcinoma Cell Survival
- (2014) Duane D. Hall et al. PLoS One
- Reconstitution of the mitochondrial calcium uniporter in yeast
- (2014) E. Kovacs-Bogdan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence
- (2014) Clotilde Wiel et al. Nature Communications
- Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells
- (2013) Merril C. Curry et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
- (2013) György Csordás et al. Cell Metabolism
- The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
- (2013) Anna Raffaello et al. EMBO JOURNAL
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- (2013) Xin Pan et al. NATURE CELL BIOLOGY
- Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
- (2013) Clare V Logan et al. NATURE GENETICS
- MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
- (2013) Molly Plovanich et al. PLoS One
- EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
- (2013) Y. Sancak et al. SCIENCE
- Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish
- (2013) Julien Prudent et al. Nature Communications
- Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter
- (2013) Guozhong Huang et al. Nature Communications
- Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
- (2013) Jing Qiu et al. Nature Communications
- MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity
- (2013) Nicholas E. Hoffman et al. Cell Reports
- MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
- (2012) Karthik Mallilankaraman et al. CELL
- Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
- (2012) Saverio Marchi et al. CURRENT BIOLOGY
- CaMKII determines mitochondrial stress responses in heart
- (2012) Mei-ling A. Joiner et al. NATURE
- Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
- (2012) Jeffrey D Martell et al. NATURE BIOTECHNOLOGY
- MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
- (2012) Karthik Mallilankaraman et al. NATURE CELL BIOLOGY
- Mitochondria as sensors and regulators of calcium signalling
- (2012) Rosario Rizzuto et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells
- (2012) Andrei I. Tarasov et al. PLoS One
- Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes
- (2012) I. Drago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- (2012) Francesca Fieni et al. Nature Communications
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
- (2011) D De Stefani et al. CELL DEATH AND DIFFERENTIATION
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels
- (2010) Marta Giacomello et al. MOLECULAR CELL
- Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface
- (2010) György Csordás et al. MOLECULAR CELL
- MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
- (2010) Fabiana Perocchi et al. NATURE
- Cancer as a metabolic disease
- (2010) Thomas N Seyfried et al. Nutrition & Metabolism
- NCLX is an essential component of mitochondrial Na+/Ca2+ exchange
- (2009) R. Palty et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now