Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
出版年份 2015 全文链接
标题
Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
作者
关键词
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出版物
Science Signaling
Volume 8, Issue 366, Pages ra23-ra23
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2015-03-04
DOI
10.1126/scisignal.2005673
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake
- (2014) A. T. Deak et al. JOURNAL OF CELL SCIENCE
- SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death
- (2014) Nicholas E. Hoffman et al. MOLECULAR BIOLOGY OF THE CELL
- MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity
- (2014) Maria Patron et al. MOLECULAR CELL
- MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
- (2013) György Csordás et al. Cell Metabolism
- The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
- (2013) Anna Raffaello et al. EMBO JOURNAL
- The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications
- (2013) Saverio Marchi et al. JOURNAL OF PHYSIOLOGY-LONDON
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- (2013) Xin Pan et al. NATURE CELL BIOLOGY
- Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
- (2013) Clare V Logan et al. NATURE GENETICS
- MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
- (2013) Molly Plovanich et al. PLoS One
- EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
- (2013) Y. Sancak et al. SCIENCE
- MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity
- (2013) Nicholas E. Hoffman et al. Cell Reports
- Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics
- (2012) Brian Glancy et al. BIOCHEMISTRY
- CaV1 and CaV2 Channels Engage Distinct Modes of Ca2+ Signaling to Control CREB-Dependent Gene Expression
- (2012) Damian G. Wheeler et al. CELL
- MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
- (2012) Karthik Mallilankaraman et al. CELL
- CRAC Channels Drive Digital Activation and Provide Analog Control and Synergy to Ca2+-Dependent Gene Regulation
- (2012) Pulak Kar et al. CURRENT BIOLOGY
- Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
- (2012) Saverio Marchi et al. CURRENT BIOLOGY
- CaMKII determines mitochondrial stress responses in heart
- (2012) Mei-ling A. Joiner et al. NATURE
- Gated regulation of CRAC channel ion selectivity by STIM1
- (2012) Beth A. McNally et al. NATURE
- MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
- (2012) Karthik Mallilankaraman et al. NATURE CELL BIOLOGY
- STIM proteins: dynamic calcium signal transducers
- (2012) Jonathan Soboloff et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria as sensors and regulators of calcium signalling
- (2012) Rosario Rizzuto et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- (2012) Francesca Fieni et al. Nature Communications
- Ca2+ signalling and gene regulation
- (2011) Anant B. Parekh et al. CELL CALCIUM
- After half a century mitochondrial calcium in- and efflux machineries reveal themselves
- (2011) Ilaria Drago et al. EMBO JOURNAL
- Mitofusin 2 Regulates STIM1 Migration from the Ca2+Store to the Plasma Membrane in Cells with Depolarized Mitochondria
- (2011) Karthika Singaravelu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis
- (2011) K. M. Irrinki et al. MOLECULAR AND CELLULAR BIOLOGY
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development
- (2011) Andre Limnander et al. NATURE IMMUNOLOGY
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- Calcium uptake mechanisms of mitochondria
- (2010) Jaime Santo-Domingo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Acidic NAADP-sensitive Calcium Stores in the Endothelium
- (2010) G. Cristina Brailoiu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Complex II Prevents Hypoxic but Not Calcium- and Proapoptotic Bcl-2 Protein-induced Mitochondrial Membrane Potential Loss
- (2010) Brian J. Hawkins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- S-glutathionylation activates STIM1 and alters mitochondrial homeostasis
- (2010) Brian J. Hawkins et al. JOURNAL OF CELL BIOLOGY
- MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
- (2010) Fabiana Perocchi et al. NATURE
- Mitochondrial calcium in health and disease
- (2009) Andrew P. Halestrap BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Regulation of mitochondrial dehydrogenases by calcium ions
- (2009) Richard M. Denton BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Decoding of Cytoplasmic Ca2+ Oscillations through the Spatial Signature Drives Gene Expression
- (2009) Joseph Di Capite et al. CURRENT BIOLOGY
- STIM1Mutation Associated with a Syndrome of Immunodeficiency and Autoimmunity
- (2009) Capucine Picard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial regulation of store-operated CRAC channels
- (2008) A PAREKH CELL CALCIUM
- Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
- (2008) Riina M. Luik et al. NATURE
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