Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project

Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression

(2016) Marta F. Estrada et al.   BIOMATERIALS

Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models

(2016) Vítor E. Santo et al.   JOURNAL OF BIOTECHNOLOGY

When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility Crisis

(2016) Jack W. Scannell et al.   PLoS One

Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids

(2016) Michaël Barbier et al.   PLoS One

Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

(2016) Kristin Stock et al.   Scientific Reports

High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts

(2015) Albin Rudisch et al.   PLoS One

Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices

(2015) Emma J. Davies et al.   Scientific Reports

Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

(2014) John A. Hickman et al.   Biotechnology Journal

An Immunohistochemical Method to Study Breast Cancer Cell Subpopulations and Their Growth Regulation by Hormones in Three-Dimensional Cultures

(2011) Mauricio P. Pinto et al.   Frontiers in Endocrinology

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL