A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts

(2016) M Cartellieri et al.   Blood Cancer Journal

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

(2015) Daniel W Lee et al.   LANCET

Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival

(2015) Sabrina Genßler et al.   OncoImmunology

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Ex Vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells

(2014) Marc Cartellieri et al.   PLoS One

Retargeting of regulatory T cells to surface-inducible autoantigen La/SS-B

(2013) Stefanie Koristka et al.   JOURNAL OF AUTOIMMUNITY

Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity?

(2013) S. J. C. van der Stegen et al.   JOURNAL OF IMMUNOLOGY

Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system

(2013) C Arndt et al.   LEUKEMIA

High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli

(2013) Kristof Zarschler et al.   Microbial Cell Factories

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

Module-assisted preparation of 64Cu with high specific activity

(2012) S. Thieme et al.   APPLIED RADIATION AND ISOTOPES

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge

(2012) Carlo G. Tocchetti et al.   EUROPEAN JOURNAL OF HEART FAILURE

Novel Humanized and Highly Efficient Bispecific Antibodies Mediate Killing of Prostate Stem Cell Antigen-Expressing Tumor Cells by CD8+ and CD4+ T Cells

(2012) A. Feldmann et al.   JOURNAL OF IMMUNOLOGY

Therapeutic stem cells expressing variants of EGFR-specific nanobodies have antitumor effects

(2012) J. A. J. M. van de Water et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

(2012) Satoe Fujiwara et al.   Journal of Ovarian Research

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

(2011) J. N. Kochenderfer et al.   BLOOD

The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer

(2011) Q Sheng et al.   BRITISH JOURNAL OF CANCER

Recommendations on management of EGFR inhibitor-induced skin toxicity: A systematic review

(2011) J.M. Baas et al.   CANCER TREATMENT REVIEWS

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

(2010) Marc Cartellieri et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Safer CARS

(2010) Helen E Heslop   MOLECULAR THERAPY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

Retargeting of T cells to prostate stem cell antigen expressing tumor cells: Comparison of different antibody formats

(2010) Anja Feldmann et al.   PROSTATE

Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction

(2008) Viswanathan Rajagopalan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The status and role of ErbB receptors in human cancer

(2008) I. Überall et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Comparison of the Biodistribution and Tumor Targeting of Two 99mTc-Labeled Anti-EGFR Nanobodies in Mice, Using Pinhole SPECT/Micro-CT

(2008) L. O. T. Gainkam et al.   JOURNAL OF NUCLEAR MEDICINE

Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways

(2008) Carlos García-Echeverría   Purinergic Signalling