Human Tregs Made Antigen Specific by Gene Modification: The Power to Treat Autoimmunity and Antidrug Antibodies with Precision
出版年份 2017 全文链接
标题
Human Tregs Made Antigen Specific by Gene Modification: The Power to Treat Autoimmunity and Antidrug Antibodies with Precision
作者
关键词
-
出版物
Frontiers in Immunology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-09-21
DOI
10.3389/fimmu.2017.01117
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Generation of human islet-specific regulatory T cells by TCR gene transfer
- (2017) Caroline M. Hull et al. JOURNAL OF AUTOIMMUNITY
- A novel method for assaying human regulatory T cell direct suppression of B cell effector function
- (2017) Elizabeth Weingartner et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis
- (2017) Xavier Montalban et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lipid-Reduction Variability and Antidrug-Antibody Formation with Bococizumab
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hemophilia A inhibitor treatment: the promise of engineered T-cell therapy
- (2017) Kalpana Parvathaneni et al. Translational Research
- CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond
- (2017) ZeNan L. Chang et al. TRENDS IN MOLECULAR MEDICINE
- A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis
- (2017) Colin J. Ross et al. Genome Medicine
- Treg adoptive therapy: is more better?
- (2016) S. Parmar et al. BLOOD
- FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII
- (2016) Jeongheon Yoon et al. BLOOD
- Regulatory T cells in cancer immunotherapy
- (2016) Atsushi Tanaka et al. CELL RESEARCH
- Safety of monoclonal antibodies for the treatment of multiple sclerosis
- (2016) Marisa P. McGinley et al. Expert Opinion On Drug Safety
- Anti-CD20 monoclonal antibodies in multiple sclerosis
- (2016) Irene Moreno Torres et al. Expert Review of Neurotherapeutics
- Improved treatment satisfaction after switching therapy to rituximab in relapsing–remitting MS
- (2016) Pierre de Flon et al. Multiple Sclerosis Journal
- Genome editing comes of age
- (2016) Jin-Soo Kim Nature Protocols
- Driving CAR T-cells forward
- (2016) Hollie J. Jackson et al. Nature Reviews Clinical Oncology
- Rituximab in multiple sclerosis
- (2016) Jonatan Salzer et al. NEUROLOGY
- Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
- (2016) C. T. Ellebrecht et al. SCIENCE
- GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing
- (2016) Liping Sun et al. Oncotarget
- Anti-CD20 monoclonal antibodies in multiple sclerosis
- (2016) Irene Moreno Torres et al. Expert Review of Neurotherapeutics
- Improved treatment satisfaction after switching therapy to rituximab in relapsing–remitting MS
- (2016) Pierre de Flon et al. Multiple Sclerosis Journal
- Retina-Specific T Regulatory Cells Bring About Resolution and Maintain Remission of Autoimmune Uveitis
- (2015) Phyllis Silver et al. JOURNAL OF IMMUNOLOGY
- Chimeric Antigen Receptor– and TCR-Modified T Cells Enter Main Street and Wall Street
- (2015) David M. Barrett et al. JOURNAL OF IMMUNOLOGY
- Categorical Analysis of Human T Cell Heterogeneity with One-Dimensional Soli-Expression by Nonlinear Stochastic Embedding
- (2015) Yang Cheng et al. JOURNAL OF IMMUNOLOGY
- Dengue virus infection elicits highly polarized CX3CR1+cytotoxic CD4+T cells associated with protective immunity
- (2015) Daniela Weiskopf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses
- (2014) Y. C. Kim et al. BLOOD
- Regulatory T cells in cancer immunotherapy
- (2014) Hiroyoshi Nishikawa et al. CURRENT OPINION IN IMMUNOLOGY
- The importance of regulatory T-cell heterogeneity in maintaining self-tolerance
- (2014) Xiaomei Yuan et al. IMMUNOLOGICAL REVIEWS
- Latency-Associated Peptide Identifies a Novel CD4+CD25+ Regulatory T Cell Subset with TGF -Mediated Function and Enhanced Suppression of Experimental Autoimmune Encephalomyelitis
- (2014) M.-L. Chen et al. JOURNAL OF IMMUNOLOGY
- Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation
- (2013) Claudio G. Brunstein et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Modulation of Treg cells/T effector function by GITR signaling is context-dependent
- (2013) Amal Ephrem et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Engineering T cells for cancer: our synthetic future
- (2013) Robert H. Vonderheide et al. IMMUNOLOGICAL REVIEWS
- Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
- (2013) Noriko Komatsu et al. NATURE MEDICINE
- Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells
- (2012) T. Kinnunen et al. BLOOD
- Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion
- (2012) Y. C. Kim et al. BLOOD
- Murine CD4+CD25- cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo
- (2012) Anna Majowicz et al. BMC GASTROENTEROLOGY
- Epistasis and immunity: the role of genetic interactions in autoimmune diseases
- (2012) Anna M. Rose et al. IMMUNOLOGY
- Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells
- (2012) M. Hagness et al. JOURNAL OF IMMUNOLOGY
- The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude
- (2012) M. K. Jenkins et al. JOURNAL OF IMMUNOLOGY
- Humoral-Targeted Immunotherapies in Multiple Sclerosis
- (2012) Sabeen Lulu et al. Neurotherapeutics
- FEIBA: A Prohemostatic Agent
- (2012) Caroline Cromwell et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Mechanisms of Treg Suppression: Still a Long Way to Go
- (2012) Dario A. A. Vignali Frontiers in Immunology
- Molecular Mechanisms of Treg-Mediated T Cell Suppression
- (2012) Angelika Schmidt et al. Frontiers in Immunology
- Hybridoma technologies for antibody production
- (2011) Masahiro Tomita et al. Immunotherapy
- Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: Studies using HLA transgenic mice
- (2011) David Luckey et al. JOURNAL OF AUTOIMMUNITY
- Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model
- (2011) Haruei Ogino et al. JOURNAL OF GASTROENTEROLOGY
- Impaired Thymic Export and Apoptosis Contribute to Regulatory T-Cell Defects in Patients with Chronic Heart Failure
- (2011) Ting-Ting Tang et al. PLoS One
- HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P
- (2010) R. A. ETTINGER et al. HAEMOPHILIA
- The spectrum of autoantibodies in IPEX syndrome is broad and includes anti-mitochondrial autoantibodies
- (2010) Masanobu Tsuda et al. JOURNAL OF AUTOIMMUNITY
- Multiple sclerosis: risk factors, prodromes, and potential causal pathways
- (2010) Sreeram V Ramagopalan et al. LANCET NEUROLOGY
- Environmental factors and their timing in adult-onset multiple sclerosis
- (2010) Adam E. Handel et al. Nature Reviews Neurology
- Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses
- (2009) R. A. Ettinger et al. BLOOD
- Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
- (2009) Ethan M. Shevach IMMUNITY
- CD27 Expression on CD4+ T Cells Differentiates Effector from Regulatory T Cell Subsets in the Lung
- (2009) D. G. Mack et al. JOURNAL OF IMMUNOLOGY
- Analysis of Adhesion Molecules, Target Cells, and Role of IL-2 in Human FOXP3+ Regulatory T Cell Suppressor Function
- (2009) D. Q. Tran et al. JOURNAL OF IMMUNOLOGY
- CD73 Is Expressed by Human Regulatory T Helper Cells and Suppresses Proinflammatory Cytokine Production andHelicobacter felis–Induced Gastritis in Mice
- (2009) Mohammad S. Alam et al. JOURNAL OF INFECTIOUS DISEASES
- Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells
- (2009) Gabriel A. Kwong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells
- (2009) R. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis
- (2009) Graham P. Wright et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Cytotoxic human CD4+ T cells
- (2008) Pablo J van de Berg et al. CURRENT OPINION IN IMMUNOLOGY
- Positioning of autoimmune TCR-Ob.2F3 and TCR-Ob.3D1 on the MBP85-99/HLA-DR2 complex
- (2008) Z. Kato et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started