The importance of regulatory T-cell heterogeneity in maintaining self-tolerance

IL-12 Signaling Drives CD8 + T Cell IFN-γ Production and Differentiation of KLRG1 + Effector Subpopulations during Toxoplasma gondii Infection

(2014) Douglas C. Wilson et al.   JOURNAL OF IMMUNOLOGY

Role of regulatory T cells during virus infection

(2013) Tamara Veiga-Parga et al.   IMMUNOLOGICAL REVIEWS

Lung-resident tissue macrophages generate Foxp3+regulatory T cells and promote airway tolerance

(2013) Pejman Soroosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Memory Regulatory T Cells Require IL-7 and Not IL-2 for Their Maintenance in Peripheral Tissues

(2013) I. K. Gratz et al.   JOURNAL OF IMMUNOLOGY

IL-2R Signaling Is Essential for Functional Maturation of Regulatory T Cells during Thymic Development

(2013) G. Cheng et al.   JOURNAL OF IMMUNOLOGY

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

(2013) Anna Cebula et al.   NATURE

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells

(2013) Wim Pierson et al.   NATURE IMMUNOLOGY

GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa

(2013) S. V. Kim et al.   SCIENCE

Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity

(2013) Mahesh Yadav et al.   Frontiers in Immunology

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

The Role of Regulatory T Cells in the Biology of Graft Versus Host Disease

(2013) Amy J. Beres et al.   Frontiers in Immunology

Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict

(2012) Robert M. Samstein et al.   CELL

Cellular and molecular determinants for the development of natural and induced regulatory T cells

(2012) Xiaomei Yuan et al.   HUMAN IMMUNOLOGY

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2

(2012) Meghan A. Koch et al.   IMMUNITY

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+T reg cells

(2012) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

(2012) Mahesh Yadav et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

IL-2 Receptor Signaling Is Essential for the Development of Klrg1+ Terminally Differentiated T Regulatory Cells

(2012) G. Cheng et al.   JOURNAL OF IMMUNOLOGY

Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

(2012) Jared H. Rowe et al.   NATURE

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

(2012) Steven Z. Josefowicz et al.   NATURE

Molecular Mechanisms of Treg-Mediated T Cell Suppression

(2012) Angelika Schmidt et al.   Frontiers in Immunology

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

(2011) Ashutosh Chaudhry et al.   IMMUNITY

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

(2011) R. A. Gottschalk et al.   JOURNAL OF IMMUNOLOGY

Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells

(2011) I. Wollenberg et al.   JOURNAL OF IMMUNOLOGY

The Basis of Distinctive IL-2– and IL-15–Dependent Signaling: Weak CD122-Dependent Signaling Favors CD8 + T Central-Memory Cell Survival but Not T Effector-Memory Cell Development

(2011) Iris Castro et al.   JOURNAL OF IMMUNOLOGY

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions

(2011) Tomoyuki Yamaguchi et al.   SEMINARS IN IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development

(2010) Weiming Ouyang et al.   IMMUNITY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

(2010) M. Feuerer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

(2009) João H. Duarte et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells Reinforce Intestinal Homeostasis

(2009) Michael J. Barnes et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

(2009) Meixiao Long et al.   IMMUNITY

A Low Interleukin-2 Receptor Signaling Threshold Supports the Development and Homeostasis of T Regulatory Cells

(2009) Aixin Yu et al.   IMMUNITY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 1

(2009) S. Z. Josefowicz et al.   JOURNAL OF IMMUNOLOGY

CARMA1 Controls an Early Checkpoint in the Thymic Development of FoxP3+ Regulatory T Cells

(2009) L. L. Molinero et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

(2009) A. Chaudhry et al.   SCIENCE

IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response

(2008) M. P. Rubinstein et al.   BLOOD

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Role of Endogenous and Induced Regulatory T Cells During Infections

(2008) Elizabeth Wohlfert et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

(2008) J. M. Lund et al.   SCIENCE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology