Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

(2016) Vanja Sisirak et al.   CELL

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations

(2016) Fariborz Mobarrez et al.   Scientific Reports

Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis

(2016) Jürgen Dieker et al.   Arthritis & Rheumatology

Neutrophils Discriminate between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps

(2016) Elmar Pieterse et al.   Frontiers in Immunology

Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation

(2016) Mona H. C. Biermann et al.   Frontiers in Immunology

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis

(2016) Jürgen Dieker et al.   PLoS One

Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN

(2015) S. V. R. Kumar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophil serine proteases exert proteolytic activity on endothelial cells

(2015) Uwe Jerke et al.   KIDNEY INTERNATIONAL

Murine and Human Lupus Nephritis: Pathogenic Mechanisms and Theoretical Strategies for Therapy

(2015) Hege Lynum Pedersen et al.   SEMINARS IN NEPHROLOGY

Acetylated histones contribute to the immunostimulatory potential of neutrophil extracellular traps in systemic lupus erythematosus

(2014) E. Pieterse et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

(2014) Mona HC Biermann et al.   Expert Review of Clinical Immunology

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Breaking Immunological Tolerance in Systemic Lupus Erythematosus

(2014) Elmar Pieterse et al.   Frontiers in Immunology

HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4

(2013) Jean-Marc Tadie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Suppression of inflammation reduces endothelial microparticles in active systemic lupus erythematosus

(2013) Ben Parker et al.   ANNALS OF THE RHEUMATIC DISEASES

Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation

(2013) Yasuyuki Arai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus

(2013) J. R. Dye et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

(2013) Jonatan Leffler et al.   ARTHRITIS RESEARCH & THERAPY

Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation

(2012) Christoffer T. Nielsen et al.   ARTHRITIS AND RHEUMATISM

Apoptosis and NET formation in the pathogenesis of SLE

(2012) Yvette M. Bouts et al.   AUTOIMMUNITY

Serum DNase I activity in systemic lupus erythematosus: correlation with immunoserological markers, the disease activity and organ involvement

(2012) Dusan Skiljevic et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

(2012) R. Allam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus

(2011) Christoffer T. Nielsen et al.   ARTHRITIS AND RHEUMATISM

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

(2011) Anirudh J. Ullal et al.   JOURNAL OF AUTOIMMUNITY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Lupus Nephritis: Role of Antinucleosome Autoantibodies

(2011) Johan van der Vlag et al.   SEMINARS IN NEPHROLOGY

Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus

(2010) C. C. van Bavel et al.   ANNALS OF THE RHEUMATIC DISEASES

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis

(2010) Svetlana N. Zykova et al.   PLoS One

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17

(2009) Justin H. Fransen et al.   ARTHRITIS AND RHEUMATISM

Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies

(2009) Casandra C. van Bavel et al.   MOLECULAR IMMUNOLOGY

Apoptosis in the pathogenesis of systemic lupus erythematosus

(2008) LE Munoz et al.   LUPUS