Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation

Factors associated with impaired quality of life in French patients with chronic idiopathic constipation

(2016) Bernard Flourié et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins

(2016) Amanda M. Pattison et al.   INFECTION AND IMMUNITY

The Spectrum of Constipation-Predominant Irritable Bowel Syndrome and Chronic Idiopathic Constipation: US Survey Assessing Symptoms, Care Seeking and Disease Burden

(2015) Joel J Heidelbaugh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Guanylate Cyclase C Agonists: Emerging Gastrointestinal Therapies and Actions

(2015) Michael Camilleri   GASTROENTEROLOGY

Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial

(2015) Brian E. Lacy et al.   PLoS One

925g Plecanatide, a Novel Guanylate Cyclase-C (GC-C) Receptor Agonist, is Efficacious and Safe in Patients with Chronic Idiopathic Constipation (CIC): Results from a 951 Patient, 12 Week, Multi-Center Trial

(2015) Philip B. Miner et al.   GASTROENTEROLOGY

Plecanatide, an Oral Guanylate Cyclase C Agonist Acting Locally in the Gastrointestinal Tract, Is Safe and Well-Tolerated in Single Doses

(2013) Kunwar Shailubhai et al.   DIGESTIVE DISEASES AND SCIENCES

Healthcare costs among patients with chronic constipation: a retrospective claims analysis in a commercially insured population

(2013) Qian Cai et al.   JOURNAL OF MEDICAL ECONOMICS

American Gastroenterological Association Medical Position Statement on Constipation

(2012) Adil E. Bharucha et al.   GASTROENTEROLOGY

Prevalence of and Risk Factors for, Chronic Idiopathic Constipation in the Community: Systematic Review and Meta-analysis

(2011) Nicole C Suares et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Uroguanylin Regulates Net Fluid Secretion via the NHE2 Isoform of the Na+/H+ Exchanger in an Intestinal Cellular Model

(2011) Roxana Toriano et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Two Randomized Trials of Linaclotide for Chronic Constipation

(2011) Anthony J. Lembo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit

(2010) Robert W. Busby et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cure and Curse: E. coli Heat-Stable Enterotoxin and Its Receptor Guanylyl Cyclase C

(2010) Philipp R. Weiglmeier et al.   Toxins

Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation - a 12-week, randomized, double-blind, placebo-controlled study

(2008) E. M. M. QUIGLEY et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives

(2008) J Tack et al.   GUT

A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation

(2008) Michael Camilleri et al.   NEW ENGLAND JOURNAL OF MEDICINE