Cure and Curse: E. coli Heat-Stable Enterotoxin and Its Receptor Guanylyl Cyclase C

Corruption of homeostatic mechanisms in the guanylyl cyclase c signaling pathway underlying colorectal tumorigenesis

(2010) Li Peng et al.   CANCER BIOLOGY & THERAPY

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract

(2010) Alexander P. Bryant et al.   LIFE SCIENCES

GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?

(2009) P. Li et al.   DRUG NEWS & PERSPECTIVES

The Hormone Receptor GUCY2C Suppresses Intestinal Tumor Formation by Inhibiting AKT Signaling

(2009) Jieru Egeria Lin et al.   GASTROENTEROLOGY

Association of GUCY2C Expression in Lymph Nodes With Time to Recurrence and Disease-Free Survival in pN0 Colorectal Cancer

(2009) Scott A. Waldman   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mechanisms of the Regulation of the IntestinalNa+/H+Exchanger NHE3

(2009) Peijian He et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The Evolution of Guanylyl Cyclases as Multidomain Proteins: Conserved Features of Kinase-Cyclase Domain Fusions

(2009) Kabir Hassan Biswas et al.   JOURNAL OF MOLECULAR EVOLUTION

Membrane guanylate cyclase is a beautiful signal transduction machine: overview

(2009) Rameshwar K. Sharma   MOLECULAR AND CELLULAR BIOCHEMISTRY

Receptor guanylyl cyclase C (GC-C): regulation and signal transduction

(2009) Nirmalya Basu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain

(2009) h. eutamene et al.   NEUROGASTROENTEROLOGY AND MOTILITY

STa peptide analogs for probing guanylyl cyclase C

(2008) Xiaobing Tian et al.   BIOPOLYMERS

Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells

(2008) Giovanni M. Pitari et al.   CARCINOGENESIS

Colorectal Cancer Is a Paracrine Deficiency Syndrome Amenable to Oral Hormone Replacement Therapy

(2008) Peng Li et al.   CTS-Clinical and Translational Science

Heat-stable enterotoxin of Escherichia coli (STa) can stimulate duodenal HCO3− secretion via a novel GC-C- and CFTR-independent pathway

(2008) Zachary M. Sellers et al.   FASEB JOURNAL

Guanylyl Cyclase C–Induced Immunotherapeutic Responses Opposing Tumor Metastases Without Autoimmunity

(2008) Adam E. Snook et al.   JNCI-Journal of the National Cancer Institute

Design and characterization of a soluble fragment of the extracellular ligand-binding domain of the peptide hormone receptor guanylyl cyclase-C

(2008) T. Lauber et al.   PROTEIN ENGINEERING DESIGN & SELECTION