Long Distance Metabolic Regulation through Adipose-Derived Circulating Exosomal miRNAs: A Trail for RNA-Based Therapies?

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Shortcuts to a functional adipose tissue: The role of small non-coding RNAs

(2017) Bruna B. Brandão et al.   Redox Biology

MicroRNAs in metabolism

(2016) S. Vienberg et al.   Acta Physiologica

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

(2016) Felipe G. et al.   Aging-US

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

(2016) Jennifer H. Stern et al.   Cell Metabolism

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery

(2016) Muhammad Nawaz et al.   Expert Review of Proteomics

Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients

(2016) Martin Torriani et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Familial partial lipodystrophy presenting as metabolic syndrome

(2016) Darwin Chan et al.   Journal of Clinical Lipidology

Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function

(2016) Matteo Oliverio et al.   NATURE CELL BIOLOGY

General rules for functional microRNA targeting

(2016) Doyeon Kim et al.   NATURE GENETICS

Extracellular Vesicles: Evolving Factors in Stem Cell Biology

(2016) Muhammad Nawaz et al.   Stem Cells International

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Obesity, insulin resistance and comorbidities ? Mechanisms of association

(2014) Ana Valeria B. Castro et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

(2014) K. R. Markan et al.   DIABETES

Cell-Specific Dysregulation of MicroRNA Expression in Obese White Adipose Tissue

(2014) Frédérik Oger et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

(2014) Marcelo A. Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The emerging role of extracellular vesicles as biomarkers for urogenital cancers

(2014) Muhammad Nawaz et al.   Nature Reviews Urology

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Decreased MicroRNA-221 is Associated with High Levels of TNF-a in Human Adipose Tissue-Derived Mesenchymal Stem Cells From Obese Woman

(2013) Wen-Wen Chou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies

(2013) Tom Nolis   JOURNAL OF HUMAN GENETICS

MicroRNA networks regulate development of brown adipocytes

(2013) Mirko Trajkovski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Consistent high concentration of the viral microRNA BART17 in plasma samples from nasopharyngeal carcinoma patients - evidence of non-exosomal transport

(2013) Claire Gourzones et al.   Virology Journal

Tumor-exosomes and leukocyte activation: an ambivalent crosstalk

(2012) Daniela Zech et al.   Cell Communication and Signaling

Role of MicroRNA Processing in Adipose Tissue in Stress Defense and Longevity

(2012) Marcelo A. Mori et al.   Cell Metabolism

Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

(2012) E. Arner et al.   DIABETES

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fibroblast growth factor 21: effects on carbohydrate and lipid metabolism in health and disease

(2011) Susan Kralisch et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Origins of metabolic complications in obesity

(2011) Bettina Mittendorfer   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Horizontal gene transfer between bacteria and animals

(2011) Julie C. Dunning Hotopp   TRENDS IN GENETICS

Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity

(2011) Pernille Keller et al.   BMC Endocrine Disorders

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

(2010) Sam Virtue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Clinical Classification and Treatment of Congenital and Acquired Lipodystrophy

(2010) Jean Chan et al.   Endocrine Practice

Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis

(2010) Lisa J. Moran et al.   HUMAN REPRODUCTION UPDATE

An essential role for Dicer in adipocyte differentiation

(2010) Rajini Mudhasani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Lipodystrophy: metabolic insights from a rare disorder

(2010) Isabel Huang-Doran et al.   JOURNAL OF ENDOCRINOLOGY

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

(2009) Tian Sheng Chen et al.   NUCLEIC ACIDS RESEARCH

FGF21 induces PGC-1  and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

(2009) M. J. Potthoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipodystrophy Syndromes

(2008) Pedro Herranz et al.   DERMATOLOGIC CLINICS

HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options

(2008) J. E. Mallewa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

Horizontal gene transfer in eukaryotic evolution

(2008) Patrick J. Keeling et al.   NATURE REVIEWS GENETICS

Insulin Secretion in Metabolically Obese, but Normal Weight, and in Metabolically Healthy but Obese Individuals

(2008) Elena Succurro et al.   Obesity