HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells

Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf

(2017) Nicola Coppola et al.   Oncotarget

HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma

(2016) Zhihao Wang et al.   CANCER LETTERS

HDAC2 overexpression is a poor prognostic factor of breast cancer patients with increased multidrug resistance-associated protein expression who received anthracyclines therapy

(2016) Haishan Zhao et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma

(2016) Christopher D. Graham et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

STAT3-survivin signaling mediates a poor response to radiotherapy in HER2-positive breast cancers

(2016) Jae-Sung Kim et al.   Oncotarget

Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells

(2016) Jane Ying-Chieh Lee et al.   Frontiers in Pharmacology

miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer via targeting BCL2, BCL2L12 and MCL1

(2015) Zhiguo Tong et al.   BIOMEDICINE & PHARMACOTHERAPY

HDAC Inhibitors Target HDAC5, Upregulate MicroRNA-125a-5p, and Induce Apoptosis in Breast Cancer Cells

(2015) Tsung-Hua Hsieh et al.   MOLECULAR THERAPY

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

(2015) Eloïse Véquaud et al.   Oncotarget

Deptor Enhances Triple-Negative Breast Cancer Metastasis and Chemoresistance through Coupling to Survivin Expression

(2015) Jenny G. Parvani et al.   NEOPLASIA

MiR-125a-3p Regulates Glioma Apoptosis and Invasion by Regulating Nrg1

(2015) Feng Yin et al.   PLoS One

HDAC 1/4-mediated silencing of microRNA-200b promotes chemoresistance in human lung adenocarcinoma cells

(2015) Dong-Qin Chen et al.   Oncotarget

YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

(2014) S M Cheng et al.   BRITISH JOURNAL OF PHARMACOLOGY

AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell

(2014) Gang Han et al.   CANCER BIOLOGY & THERAPY

Reduced miR-125a-5p expression is associated with gastric carcinogenesis through the targeting of E2F3

(2014) YANJUN XU et al.   Molecular Medicine Reports

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53 -mutated breast cancers

(2014) Balázs Győrffy et al.   Molecular Oncology

Overexpression of the Survivin gene in SGC7901 cell resistance to cisplatin

(2014) HANZHANG DONG et al.   Oncology Letters

Treat cancers by targeting survivin: Just a dream or future reality?

(2013) Mohane Selvaraj Coumar et al.   CANCER TREATMENT REVIEWS

The p53-Estrogen Receptor Loop in Cancer

(2013) C. Berger et al.   CURRENT MOLECULAR MEDICINE

Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer

(2013) Xue-Pu Sun et al.   FEBS Journal

The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis

(2013) Matteo Fassan et al.   HUMAN PATHOLOGY

Oestrogen receptor α mediates 17β-estradiol enhancement of ovarian cancer cell motility through up-regulation of survivin expression

(2012) Jing Zhu et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Distincttumor protein p53mutants in breast cancer subgroups

(2012) Anne Dumay et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy Controls p38 Activation to Promote Cell Survival under Genotoxic Stress

(2012) Lei Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Gene Expression in Tamoxifen-Resistant Breast Cancer Cells Revealed by a New Analytical Model of RNA-Seq Data

(2012) Kathryn J. Huber-Keener et al.   PLoS One

Estrogen receptor prevents p53-dependent apoptosis in breast cancer

(2012) S. T. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sp1 Upregulates Survivin Expression in Adenocarcinoma of Lung Cell Line A549

(2011) Yuqing Chen et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer

(2011) E. A. Stronach et al.   CANCER RESEARCH

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity

(2010) Euphemia Leung et al.   CANCER BIOLOGY & THERAPY

Survivin regulation by HER2 through NF-κB and c-myc in irradiated breast cancer cells

(2010) Vassilis Papanikolaou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Involvement of mTOR and survivin inhibition in tamoxifen-induced apoptosis in human hepatoblastoma cell line HepG2

(2009) Renhua Guo et al.   BIOMEDICINE & PHARMACOTHERAPY

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

(2009) Chun Hei Antonio Cheung et al.   Molecular Cancer

MCF-7 breast carcinoma cells do not express caspase-3

(2008) Reiner U. Jänicke   BREAST CANCER RESEARCH AND TREATMENT