HIV-1 gp41-targeting fusion inhibitory peptides enhance the gp120-targeting protein-mediated inactivation of HIV-1 virions

ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer

(2014) Fei Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance

(2014) Huihui Chong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

(2014) Datsen George Wei et al.   PLoS Pathogens

Engineered Soluble Monomeric IgG1 CH3 Domain

(2013) Tianlei Ying et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exceptionally Potent and Broadly Cross-Reactive, Bispecific Multivalent HIV-1 Inhibitors Based on Single Human CD4 and Antibody Domains

(2013) W. Chen et al.   JOURNAL OF VIROLOGY

Role of Human CD4 D1D2 Domain in HIV-1 Infection

(2012) Lan Li et al.   IMMUNOLOGICAL INVESTIGATIONS

A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains

(2012) Lu Lu et al.   Retrovirology

Engineered Single Human CD4 Domains as Potent HIV-1 Inhibitors and Components of Vaccine Immunogens

(2011) W. Chen et al.   JOURNAL OF VIROLOGY

Resistance of Human Immunodeficiency Virus Type 1 to a Third-Generation Fusion Inhibitor Requires Multiple Mutations in gp41 and Is Accompanied by a Dramatic Loss of gp41 Function

(2011) D. Eggink et al.   JOURNAL OF VIROLOGY

Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates

(2010) Weizao Chen et al.   ANTIVIRAL RESEARCH

sCD4-17b bifunctional protein: Extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates

(2010) Laurel A Lagenaur et al.   Retrovirology

Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State

(2009) Hillel Haim et al.   PLoS Pathogens

Design and Evaluation of Sifuvirtide, a Novel HIV-1 Fusion Inhibitor

(2008) Yuxian He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers

(2008) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA