Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice

Synovial macrophages promote TGF-β signaling and protect against influx of S100A8/S100A9-producing cells after intra-articular injections of oxidized low-density lipoproteins

(2017) W. de Munter et al.   OSTEOARTHRITIS AND CARTILAGE

Dietary Fat Intake and Radiographic Progression of Knee Osteoarthritis: Data From the Osteoarthritis Initiative

(2017) Bing Lu et al.   ARTHRITIS CARE & RESEARCH

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

(2016) Kylie Anne Alexander et al.   IMMUNOLOGY AND CELL BIOLOGY

Review: Metabolic Regulation of Inflammation in Osteoarthritis

(2016) Francis Berenbaum et al.   Arthritis & Rheumatology

Obesity and the Relative Risk of Knee Replacement Surgery in Patients With Knee Osteoarthritis: A Prospective Cohort Study

(2016) Kirsten M. Leyland et al.   Arthritis & Rheumatology

Response to diet-induced obesity produces time-dependent induction and progression of metabolic osteoarthritis in rat knees

(2015) Kelsey H. Collins et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

High systemic levels of low-density lipoprotein cholesterol: fuel to the flames in inflammatory osteoarthritis?

(2015) Wouter de Munter et al.   RHEUMATOLOGY

Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury

(2014) Chia-Lung Wu et al.   ANNALS OF THE RHEUMATIC DISEASES

Social networking of human neutrophils within the immune system

(2014) P. Scapini et al.   BLOOD

Human S100A9 potentiates IL-8 production in response to GM-CSF or fMLP via activation of a different set of transcription factors in neutrophils

(2014) Jean-Christophe Simard et al.   FEBS LETTERS

IL-27 Induces a Th1 Immune Response and Susceptibility to Experimental Arthritis

(2014) Y. Cao et al.   JOURNAL OF IMMUNOLOGY

Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo

(2014) M. K. Chang et al.   JOURNAL OF IMMUNOLOGY

The multifactorial role of neutrophils in rheumatoid arthritis

(2014) Helen L. Wright et al.   Nature Reviews Rheumatology

Mouse models of osteoarthritis: modelling risk factors and assessing outcomes

(2014) Hang Fang et al.   Nature Reviews Rheumatology

Influences of alignment and obesity on knee joint loading in osteoarthritic gait

(2014) S.P. Messier et al.   OSTEOARTHRITIS AND CARTILAGE

Macrophage Depletion Disrupts Immune Balance and Energy Homeostasis

(2014) Bonggi Lee et al.   PLoS One

Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells

(2013) H. Matsushima et al.   BLOOD

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis

(2013) Richard F. Loeser et al.   PLoS One

Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice

(2012) Craig R. Louer et al.   ARTHRITIS AND RHEUMATISM

Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice

(2012) John S. Lewis et al.   ARTHRITIS AND RHEUMATISM

Production of interleukin-27 by human neutrophils regulates their function during bacterial infection

(2012) Darawan Rinchai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1

(2012) Kiyoshi Hirahara et al.   IMMUNITY

Treatment of arthritis by macrophage depletion and immunomodulation: Testing an apoptosis-mediated therapy in a humanized death receptor mouse model

(2011) Jun Li et al.   ARTHRITIS AND RHEUMATISM

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice

(2011) Bin Feng et al.   PLoS One

Regulation of steady-state neutrophil homeostasis by macrophages

(2010) C. Gordy et al.   BLOOD

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice

(2010) Pingping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

(2010) D. A. Hume   JOURNAL OF LEUKOCYTE BIOLOGY

The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review

(2010) S. Clockaerts et al.   OSTEOARTHRITIS AND CARTILAGE

Human Adipose Tissue Macrophages: M1 and M2 Cell Surface Markers in Subcutaneous and Omental Depots and after Weight Loss

(2009) Judith Aron-Wisnewsky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

(2008) David Patsouris et al.   Cell Metabolism