Association of MicroRNA-618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis

Undifferentiated Connective Tissue Disease at risk for systemic sclerosis (SSc) (so far referred to as very early/early SSc or pre-SSc)

(2015) Gabriele Valentini   AUTOIMMUNITY REVIEWS

Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis

(2015) Maria Arismendi et al.   ARTHRITIS RESEARCH & THERAPY

Systemic sclerosis

(2015) Yannick Allanore et al.   Nature Reviews Disease Primers

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of genetics and epigenetics in the pathogenesis of systemic sclerosis

(2014) Jasper C. A. Broen et al.   Nature Reviews Rheumatology

T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?

(2014) Zana Brkic et al.   ARTHRITIS RESEARCH & THERAPY

2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative

(2013) Frank van den Hoogen et al.   ARTHRITIS AND RHEUMATISM

IRF-5 and NF-κB p50 co-regulate IFN-β and IL-6 expression in TLR9-stimulated human plasmacytoid dendritic cells

(2013) Folkert Steinhagen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?

(2013) Karin Pelka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The critical importance of epigenetics in autoimmunity

(2013) Qianjin Lu   JOURNAL OF AUTOIMMUNITY

In Vivo Ablation of Plasmacytoid Dendritic Cells Inhibits Autoimmunity through Expansion of Myeloid-Derived Suppressor Cells

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Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis

(2013) Lenny van Bon et al.   NEW ENGLAND JOURNAL OF MEDICINE

ComiR: combinatorial microRNA target prediction tool

(2013) Claudia Coronnello et al.   NUCLEIC ACIDS RESEARCH

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

(2013) R. Baccala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlation of interferon-inducible chemokine plasma levels with disease severity in systemic sclerosis

(2012) Xiaochun Liu et al.   ARTHRITIS AND RHEUMATISM

PLD4as a novel susceptibility gene for systemic sclerosis in a Japanese population

(2012) Chikashi Terao et al.   ARTHRITIS AND RHEUMATISM

Intrinsic Gene Expression Subsets of Diffuse Cutaneous Systemic Sclerosis Are Stable in Serial Skin Biopsies

(2012) Sarah A. Pendergrass et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

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IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

(2011) Olga Gorlova et al.   PLoS Genetics

Type I interferon system activation and association with disease manifestations in systemic sclerosis

(2010) M.-L. Eloranta et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation of the type I interferon pathway in primary Sjogren’s syndrome

(2010) Clio P. Mavragani et al.   JOURNAL OF AUTOIMMUNITY

Cholera toxin inhibits IL-12 production and CD8α+dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

(2009) Andrea la Sala et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Induction of interferon‐α by scleroderma sera containing autoantibodies to topoisomerase I: Association of higher interferon‐α activity with lung fibrosis

(2008) Daniel Kim et al.   ARTHRITIS AND RHEUMATISM

The innate immune system in SLE: type I interferons and dendritic cells

(2008) L Rönnblom et al.   LUPUS

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE