The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy
出版年份 2017 全文链接
标题
The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy
作者
关键词
-
出版物
Translational Psychiatry
Volume 7, Issue 12, Pages -
出版商
Springer Nature
发表日期
2017-12-15
DOI
10.1038/s41398-017-0017-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model
- (2017) E Lauretti et al. Translational Psychiatry
- Neuroinflammation in Alzheimer's Disease and Mild Cognitive Impairment: A Field in Its Infancy
- (2017) Edith G. McGeer et al. JOURNAL OF ALZHEIMERS DISEASE
- Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
- (2016) Cyril Laurent et al. BRAIN
- Tau and tauopathies
- (2016) Thomas Arendt et al. BRAIN RESEARCH BULLETIN
- Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options
- (2016) Ruth Lamb et al. Current Treatment Options in Neurology
- Progressive tauopathy in P301S tau transgenic mice is associated with a functional deficit of the olfactory system
- (2016) Sujeong Yang et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy
- (2015) Phillip F. Giannopoulos et al. BIOLOGICAL PSYCHIATRY
- Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles
- (2014) Jian-Guo Li et al. ANNALS OF NEUROLOGY
- Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease
- (2014) Y. B. Joshi et al. HUMAN MOLECULAR GENETICS
- Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice
- (2014) Antonio Di Meco et al. NEUROBIOLOGY OF AGING
- Tau pathology and neurodegeneration
- (2013) Maria Grazia Spillantini et al. LANCET NEUROLOGY
- Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease
- (2013) P F Giannopoulos et al. MOLECULAR PSYCHIATRY
- 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease
- (2012) Jin Chu et al. ANNALS OF NEUROLOGY
- Microglia and Inflammation in Alzheimers Disease
- (2012) Shweta Mandrekar-Colucci et al. CNS & Neurological Disorders-Drug Targets
- Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice
- (2012) Jin Chu et al. Molecular Neurodegeneration
- Pharmacologic Blockade of 5-Lipoxygenase Improves the Amyloidotic Phenotype of an Alzheimer's Disease Transgenic Mouse Model
- (2011) Jin Chu et al. AMERICAN JOURNAL OF PATHOLOGY
- Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
- (2011) A. Sydow et al. JOURNAL OF NEUROSCIENCE
- 5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo
- (2010) Jin Chu et al. ANNALS OF NEUROLOGY
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- 5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer’s disease
- (2007) Omidreza Firuzi et al. FASEB JOURNAL
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