标题
An Overview of Lipid Droplets in Cancer and Cancer Stem Cells
作者
关键词
-
出版物
Stem Cells International
Volume 2017, Issue -, Pages 1-17
出版商
Hindawi Limited
发表日期
2017-08-14
DOI
10.1155/2017/1656053
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Perilipins: a diversity of intracellular lipid droplet proteins
- (2017) Hiroyuki Itabe et al. Lipids in Health and Disease
- Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells
- (2017) Catharina Melzer et al. Molecular Cancer
- Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
- (2017) A Noto et al. ONCOGENE
- Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets
- (2016) Sandra Heller et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6
- (2016) Harrison Penrose et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism
- (2016) Yanyan Cai et al. CANCER CELL
- Rab proteins as regulators of lipid droplet formation and lipolysis
- (2016) Chunman Li et al. CELL BIOLOGY INTERNATIONAL
- Lipid droplets in leukocytes: Organelles linked to inflammatory responses
- (2016) Rossana C.N. Melo et al. EXPERIMENTAL CELL RESEARCH
- Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes
- (2016) Wenyi Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PML isoform II plays a critical role in nuclear lipid droplet formation
- (2016) Yuki Ohsaki et al. JOURNAL OF CELL BIOLOGY
- Perilipin 5 restores the formation of lipid droplets in activated hepatic stellate cells and inhibits their activation
- (2016) Jianguo Lin et al. LABORATORY INVESTIGATION
- Tissue-specific designs of stem cell hierarchies
- (2016) Jane E. Visvader et al. NATURE CELL BIOLOGY
- Using Raman spectroscopy to characterize biological materials
- (2016) Holly J Butler et al. Nature Protocols
- Control of YAP/TAZ Activity by Metabolic and Nutrient-Sensing Pathways
- (2016) Giulia Santinon et al. TRENDS IN CELL BIOLOGY
- Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets
- (2016) Nora Kory et al. TRENDS IN CELL BIOLOGY
- Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review
- (2016) Ken-ichi Ito et al. OncoTargets and Therapy
- Fatty acid synthase regulates invasion and metastasis of colorectal cancer via Wnt signaling pathway
- (2016) Haiyu Wang et al. Cancer Medicine
- Interplay between Inflammation and Stemness in Cancer Cells: The Role of Toll-Like Receptor Signaling
- (2016) Da-Wei Yeh et al. Journal of Immunology Research
- Melanoma Cancer Stem Cells: Markers and Functions
- (2016) Giorgio Parmiani Cancers
- Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells
- (2016) Yuki Yasumoto et al. PLoS One
- Lipid droplets regulate autophagosome biogenesis
- (2015) Tomer Shpilka et al. Autophagy
- MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
- (2015) Patricia Sancho et al. Cell Metabolism
- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Expanding Roles for Lipid Droplets
- (2015) Michael A. Welte CURRENT BIOLOGY
- The role for autophagy in cancer
- (2015) Eileen White JOURNAL OF CLINICAL INVESTIGATION
- Letter to the Editor:An Intriguing Relationship Between Lipid Droplets, Cholesterol-Binding Protein CD133 and Wnt/β-Catenin Signaling Pathway in Carcinogenesis
- (2015) Germana Rappa et al. STEM CELLS
- Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration
- (2015) Yekaterina Y. Zaytseva et al. Oncotarget
- Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts
- (2015) Suhas D. Darekar et al. Oncotarget
- FTIR spectroscopy reveals lipid droplets in drug resistant laryngeal carcinoma cells through detection of increased ester vibrational bands intensity
- (2014) Sanjica Rak et al. ANALYST
- Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity
- (2014) Peng Sun et al. BMC CANCER
- Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness
- (2014) Shuhua Yue et al. Cell Metabolism
- Lipid droplet biogenesis
- (2014) Florian Wilfling et al. CURRENT OPINION IN CELL BIOLOGY
- Raman and coherent anti-Stokes Raman scattering microscopy studies of changes in lipid content and composition in hormone-treated breast and prostate cancer cells
- (2014) Mariana C. Potcoava et al. JOURNAL OF BIOMEDICAL OPTICS
- Biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites
- (2014) Albert Pol et al. JOURNAL OF CELL BIOLOGY
- Recent Advances in Understanding Proteins Involved in Lipid Droplet Formation, Growth and Fusion
- (2014) Jolene S.Y. Tan et al. Journal of Genetics and Genomics
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- Metabolic requirements for the maintenance of self-renewing stem cells
- (2014) Keisuke Ito et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lipid Droplets: A New Player in Colorectal Cancer Stem Cells Unveiled by Spectroscopic Imaging
- (2014) Luca Tirinato et al. STEM CELLS
- Lysosome: regulator of lipid degradation pathways
- (2014) Carmine Settembre et al. TRENDS IN CELL BIOLOGY
- Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting
- (2014) Florian Wilfling et al. eLife
- Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice
- (2013) Weiqin Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes
- (2013) Tan Hooi Min Grahn et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Perilipins: Lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection
- (2013) Carole Sztalryd et al. BIOCHIMIE
- LGR5 positivity defines stem-like cells in colorectal cancer
- (2013) Daniela Hirsch et al. CARCINOGENESIS
- TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence
- (2013) Ilana Chefetz et al. CELL CYCLE
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity
- (2013) Albert Herms et al. CURRENT BIOLOGY
- Lipid droplet metabolism
- (2013) Victor K. Khor et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets
- (2013) Florian Wilfling et al. DEVELOPMENTAL CELL
- Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
- (2013) F. Baenke et al. Disease Models & Mechanisms
- Balancing the fat: lipid droplets and human disease
- (2013) Natalie Krahmer et al. EMBO Molecular Medicine
- Energy Metabolism Characterization of a Novel Cancer Stem Cell-Like Line 3AB-OS
- (2013) Roberta Palorini et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
- (2013) James L. McManaman et al. JOURNAL OF LIPID RESEARCH
- Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier
- (2013) Nina M. Pollak et al. JOURNAL OF LIPID RESEARCH
- Autophagosomes contribute to intracellular lipid distribution in enterocytes
- (2013) Salem Ait Khaldoun et al. MOLECULAR BIOLOGY OF THE CELL
- Cancer stem cells: The challenges ahead
- (2013) Jan Paul Medema NATURE CELL BIOLOGY
- Self-renewal as a therapeutic target in human colorectal cancer
- (2013) Antonija Kreso et al. NATURE MEDICINE
- Perilipin-Mediated Lipid Droplet Formation in Adipocytes Promotes Sterol Regulatory Element-Binding Protein-1 Processing and Triacylglyceride Accumulation
- (2013) Yu Takahashi et al. PLoS One
- MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
- (2013) H. Zirath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains
- (2013) R. Volmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells
- (2013) H Liu et al. Cell Death & Disease
- Lipid Droplets and Cellular Lipid Metabolism
- (2012) Tobias C. Walther et al. Annual Review of Biochemistry
- CIDE Proteins and Lipid Metabolism
- (2012) Li Xu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Detection of Lipid-Rich Prostate Circulating Tumour Cells with Coherent Anti-Stokes Raman Scattering Microscopy
- (2012) Ranjana Mitra et al. BMC CANCER
- The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas
- (2012) F Seguin et al. BRITISH JOURNAL OF CANCER
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
- (2012) Rudolf Zechner et al. Cell Metabolism
- Inflammation and Lipid Signaling in the Etiology of Insulin Resistance
- (2012) Christopher K. Glass et al. Cell Metabolism
- Lipid metabolism in cancer
- (2012) Claudio R. Santos et al. FEBS Journal
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- NF-κB and the link between inflammation and cancer
- (2012) Joseph A. DiDonato et al. IMMUNOLOGICAL REVIEWS
- Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation
- (2012) Kenta Kuramoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets
- (2012) Kai Hsieh et al. JOURNAL OF CELL SCIENCE
- Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways
- (2012) Shurong Huang et al. JOURNAL OF LIPID RESEARCH
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Dclk1 distinguishes between tumor and normal stem cells in the intestine
- (2012) Yuki Nakanishi et al. NATURE GENETICS
- The role of aspirin in cancer prevention
- (2012) Michael J. Thun et al. Nature Reviews Clinical Oncology
- The Lipid Phenotype of Breast Cancer Cells Characterized by Raman Microspectroscopy: Towards a Stratification of Malignancy
- (2012) Claudia Nieva et al. PLoS One
- Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas
- (2012) A. G. Schepers et al. SCIENCE
- Lipid-rich carcinoma of the breast clinicopathologic analysis of 17 cases
- (2011) Bing Guan et al. Annals of Diagnostic Pathology
- Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
- (2011) M. Hilvo et al. CANCER RESEARCH
- The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells
- (2011) Michelangelo Cordenonsi et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification
- (2011) Caryl J. Antalis et al. CLINICAL & EXPERIMENTAL METASTASIS
- Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites
- (2011) Jingyi Gong et al. JOURNAL OF CELL BIOLOGY
- Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
- (2011) Hong Wang et al. JOURNAL OF LIPID RESEARCH
- Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis
- (2011) Naoki Omae et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells
- (2011) W.-C. Huang et al. MOLECULAR CANCER RESEARCH
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Role of Rab GTPases in Membrane Traffic and Cell Physiology
- (2011) Alex H. Hutagalung et al. PHYSIOLOGICAL REVIEWS
- Interaction between the Triglyceride Lipase ATGL and the Arf1 Activator GBF1
- (2011) Emy Njoh Ellong et al. PLoS One
- FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation
- (2011) Srikarthika Jambunathan et al. PLoS One
- The utility of Aspirin in dukes C and high risk dukes B colorectal cancer - The ASCOLT study: study protocol for a randomized controlled trial
- (2011) Raghib Ali et al. Trials
- Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase
- (2010) Puspa R. Pandey et al. BREAST CANCER RESEARCH AND TREATMENT
- TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma
- (2010) Judit Anido et al. CANCER CELL
- De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
- (2010) E. Rysman et al. CANCER RESEARCH
- The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase
- (2010) Xingyuan Yang et al. Cell Metabolism
- Lipid droplets: A dynamic organelle moves into focus
- (2010) Mathias Beller et al. FEBS LETTERS
- Lipid droplets lighting up: Insights from live microscopy
- (2010) Margarete Digel et al. FEBS LETTERS
- Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase
- (2010) James G. Granneman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones
- (2010) Jie Hu et al. Nutrition & Metabolism
- Metabolism and proliferation share common regulatory pathways in cancer cells
- (2010) V Fritz et al. ONCOGENE
- Acyl-coenzyme A:cholesterol acyltransferases
- (2009) Ta-Yuan Chang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis
- (2009) Kazuharu Takeuchi et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- TIP47, a Lipid Cargo Protein Involved in Macrophage Triglyceride Metabolism
- (2009) Insa Buers et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
- (2009) Perry E. Bickel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Coherent anti-Stokes Raman scattering imaging of lipids in cancer metastasis
- (2009) Thuc T Le et al. BMC CANCER
- Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
- (2009) E. H. Huang et al. CANCER RESEARCH
- Lipid Droplets Finally Get a Little R-E-S-P-E-C-T
- (2009) Robert V. Farese et al. CELL
- Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis
- (2009) Daniel K. Nomura et al. CELL
- Lipid droplets interact with mitochondria using SNAP23
- (2009) Sara Jägerström et al. CELL BIOLOGY INTERNATIONAL
- Adipophilin protein expression in muscle - a possible protective role against insulin resistance
- (2009) Janneke de Wilde et al. FEBS Journal
- Diacylglycerol Enrichment of Endoplasmic Reticulum or Lipid Droplets Recruits Perilipin 3/TIP47 during Lipid Storage and Mobilization
- (2009) James R. Skinner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lipid droplets at a glance
- (2009) Y. Guo et al. JOURNAL OF CELL SCIENCE
- Proteomic insights into an expanded cellular role for cytoplasmic lipid droplets
- (2009) Brittany D. M. Hodges et al. JOURNAL OF LIPID RESEARCH
- MRPS18-2 protein immortalizes primary rat embryonic fibroblasts and endows them with stem cell-like properties
- (2009) E. Kashuba et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors
- (2009) M. Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
- (2009) G. Bertolini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid droplets as dynamic organelles connecting storage and efflux of lipids
- (2008) Sven-Olof Olofsson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lipid Bodies Are Reservoirs of Cyclooxygenase-2 and Sites of Prostaglandin-E2 Synthesis in Colon Cancer Cells
- (2008) M. T. Accioly et al. CANCER RESEARCH
- SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
- (2008) Thomas Porstmann et al. Cell Metabolism
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Induction of myeloid-derived suppressor cells by tumor exosomes
- (2008) Xiaoyu Xiang et al. INTERNATIONAL JOURNAL OF CANCER
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic Melanoma
- (2008) Germana Rappa et al. STEM CELLS
- Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets
- (2008) Lars Kuerschner et al. TRAFFIC
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